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Index > Protein center > HAAO(Gene name) > Human
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  • HAAO (Gene name),
  • 3-hydroxyanthranilate 3,4-dioxygenase (Protein name ),  3HAO_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    HAAO;
    Protein name:
    3-hydroxyanthranilate 3,4-dioxygenase;
    Alternative:
    3-hydroxyanthranilic acid dioxygenase(HAD);3-hydroxyanthranilate oxygenase(3-HAO);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer.
    Function:
    Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    286
    Sequence:
    50:
    MERRLGVRAW | VKENRGSFQP | PVCNKLMHQE | QLKVMFIGGP | NTRKDYHIEE | 
    100:
    GEEVFYQLEG | DMVLRVLEQG | KHRDVVIRQG | EIFLLPARVP | HSPQRFANTV | 
    150:
    GLVVERRRLE | TELDGLRYYV | GDTMDVLFEK | WFYCKDLGTQ | LAPIIQEFFS | 
    200:
    SEQYRTGKPI | PDQLLKEPPF | PLSTRSIMEP | MSLDAWLDSH | HRELQAGTPL | 
    250:
    SLFGDTYETQ | VIAYGQGSSE | GLRQNVDVWL | WQLEGSSVVT | MGGRRLSLAP | 
    286:
    DDSLLVLAGT | SYAWERTQGS | VALSVTQDPA | CKKPLG
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    KEGG:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    MSDS:
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    ELISA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    E10868h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    E10868m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    E10868r
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    Packing:
    96T
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    CLIA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    U10868h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    MSDS:
    Please sign in first.
    CLIA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    U10868m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    U10868r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Polyclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Polyclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Polyclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Cat.:
    P10868Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Monoclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Monoclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Monoclonal Antibody for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Protein for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Protein for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Protein for Human 3-hydroxyanthranilate 3,4-dioxygenase
    Protein for Human 3-hydroxyanthranilate 3,4-dioxygenase

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    References
    1. 1.
      "Molecular cloning and functional expression of human 3-hydroxyanthranilic-acid dioxygenase."
      Malherbe P. , Kohler C. , da Prada M. , Lang G. , Kiefer V. , Schwarcz R. , Lahm H. , Cesura A.M.
      J. Biol. Chem.269:13792-13797(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;CATALYTIC ACTIVITY;COFACTOR;VARIANT VAL-37
    2. 2.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Ebert L. , Schick M. , Neubert P. , Schatten R. , Henze S. , Korn B.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-37
    3. 3.
      "Full-length cDNA libraries and normalization."
      Li W.B. , Gruber C. , Jessee J. , Polayes D.
      Submitted (2004-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Placenta.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Hippocampus.
    5. 5.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT VAL-37
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    8. 8.
      "Crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenase."
      Center for eukaryotic structural genomics (CESG)
      Submitted (2007-08) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.6 ANGSTROMS) IN COMPLEX WITH NICKEL IONS
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