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Index > Protein center > SLC3A2(Gene name) > Human
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  • SLC3A2 (Gene name),
  • 4F2 cell-surface antigen heavy chain (Protein name ),  4F2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SLC3A2(MDU1);
    Protein name:
    4F2 cell-surface antigen heavy chain(4F2hc);
    Alternative:
    Lymphocyte activation antigen 4F2 large subunit;4F2 heavy chain antigen;Solute carrier family 3 member 2;
    CD:
    CD98;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Disulfide-linked heterodimer of a glycosylated heavy chain and a non-glycosylated light chain (SLC7A5, SLC7A6, SLCA7A7, SLC7A8, SLC7A10 or SLCA7A11). Colocalizes with cadherins (By similarity). Interacts with FAM57A/CT120 and ICAM1. Constitutively and specifically associates with beta-1 integrins (alpha-2/beta-1, alpha-3/beta-1, alpha-5/beta-1 and alpha-6/beta-1), but minimally with alpha-4/beta-1.
    Function:
    Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier.
    Subcellular Location:
    Apical cell membrane Single-pass type II membrane protein Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Localized to the plasma membrane when associated with SLC7A5 or SLC7A8. Localized to the placental apical membrane. Located selectively at cell-cell adhesion sites (By similarity). Colocalized with SLC7A8/LAT2 at the basolateral membrane of kidney proximal tubules and small intestine epithelia. Expressed in both luminal and abluminal membranes of brain capillary endothelial cells.
    Protein Attributes:
    Sequence length:
    630
    Sequence:
    50:
    MELQPPEASI | AVVSIPRQLP | GSHSEAGVQG | LSAGDDSELG | SHCVAQTGLE | 
    100:
    LLASGDPLPS | ASQNAEMIET | GSDCVTQAGL | QLLASSDPPA | LASKNAEVTG | 
    150:
    TMSQDTEVDM | KEVELNELEP | EKQPMNAASG | AAMSLAGAEK | NGLVKIKVAE | 
    200:
    DEAEAAAAAK | FTGLSKEELL | KVAGSPGWVR | TRWALLLLFW | LGWLGMLAGA | 
    250:
    VVIIVRAPRC | RELPAQKWWH | TGALYRIGDL | QAFQGHGAGN | LAGLKGRLDY | 
    300:
    LSSLKVKGLV | LGPIHKNQKD | DVAQTDLLQI | DPNFGSKEDF | DSLLQSAKKK | 
    350:
    SIRVILDLTP | NYRGENSWFS | TQVDTVATKV | KDALEFWLQA | GVDGFQVRDI | 
    400:
    ENLKDASSFL | AEWQNITKGF | SEDRLLIAGT | NSSDLQQILS | LLESNKDLLL | 
    450:
    TSSYLSDSGS | TGEHTKSLVT | QYLNATGNRW | CSWSLSQARL | LTSFLPAQLL | 
    500:
    RLYQLMLFTL | PGTPVFSYGD | EIGLDAAALP | GQPMEAPVML | WDESSFPDIP | 
    550:
    GAVSANMTVK | GQSEDPGSLL | SLFRRLSDQR | SKERSLLHGD | FHAFSAGPGL | 
    600:
    FSYIRHWDQN | ERFLVVLNFG | DVGLSAGLQA | SDLPASASLP | AKADLLLSTQ | 
    630:
    PGREEGSPLE | LERLKLEPHE | GLLLRFPYAA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    KEGG:
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human 4F2hc
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    E2005h
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    ELISA Kit for Human 4F2hc
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    ELISA Kit for Human 4F2hc
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    E2005r
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    ELISA Kit for Human 4F2hc
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    E2005m
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    96T
    CLIA Kit for Human 4F2hc
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    U2005h
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    CLIA Kit for Human 4F2hc
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    MSDS:
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    Packing:
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    CLIA Kit for Human 4F2hc
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    CLIA Kit for Human 4F2hc
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    U2005r
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    Packing:
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    Polyclonal Antibody for Human 4F2hc
    Polyclonal Antibody for Human 4F2hc
    Cat.:
    P2005Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 4F2hc
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    P2005Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human 4F2hc
    Cat.:
    P2005Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human 4F2hc
    Monoclonal Antibody for Human 4F2hc
    Monoclonal Antibody for Human 4F2hc
    Monoclonal Antibody for Human 4F2hc
    Protein for Human 4F2hc
    Protein for Human 4F2hc
    Protein for Human 4F2hc
    Protein for Human 4F2hc

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth."
      Quackenbush E. , Clabby M. , Gottesdiener K.M. , Barbosa J. , Jones N.H. , Strominger J.L. , Speck S. , Leiden J.M.
      Proc. Natl. Acad. Sci. U.S.A.84:6526-6530(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM;SEQUENCE REVISION
    3. 3.
      "Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus."
      Teixeira S. , di Grandi S. , Kuehn L.C.
      J. Biol. Chem.262:9574-9580(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    4. 4.
      "Cloning, sequence analysis, and expression of the large subunit of the human lymphocyte activation antigen 4F2."
      Lumadue J.A. , Glick A.B. , Ruddle F.H.
      Proc. Natl. Acad. Sci. U.S.A.84:9204-9208(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;INDUCTION
      tissue: Fibroblast.
    5. 5.
      "Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation."
      Gottesdiener K.M. , Karpinski B.A. , Lindsten T. , Strominger J.L. , Jones N.H. , Thompson C.B. , Leiden J.M.
      Mol. Cell. Biol.8:3809-3819(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 2);TISSUE SPECIFICITY;INDUCTION
    6. 6.
      "Human L-type amino acid transporter 1 (LAT1): characterization of function and expression in tumor cell lines."
      Yanagida O. , Kanai Y. , Chairoungdua A. , Kim D.K. , Segawa H. , Nii T. , Cha S.H. , Matsuo H. , Fukushima J. , Fukasawa Y. , Tani Y. , Taketani Y. , Uchino H. , Kim J.Y. , Inatomi J. , Okayasu I. , Miyamoto K. , Takeda E. , more...
      Biochim. Biophys. Acta1514:291-302(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBUNIT;TISSUE SPECIFICITY
      tissue: Placenta.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 4)
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Lung.
      tissue: Placenta.
    9. 9.
      Bienvenut W.V. , Lao L. , Ryan K.L.
      Submitted (2009-10) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-17; 146-171; 227-245; 304-313; 440-451; 511-525 AND 593-630;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Cervix carcinoma.
    10. 10.
      Strausberg R.L.
      Submitted (2000-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 83-209 (ISOFORM 4)
      tissue: Lung carcinoma.
    11. 11.
      Bienvenut W.V.
      Submitted (2005-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 112-122; 148-160; 227-245; 248-255; 288-298; 304-313; 440-451; 511-524 AND 593-625;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: B-cell lymphoma.
    12. 12.
      "Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance."
      Torrents D. , Estevez R. , Pineda M. , Fernandez E. , Lloberas J. , Shi Y.-B. , Zorzano A. , Palacin M.
      J. Biol. Chem.273:32437-32445(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;INHIBITION;MUTAGENESIS OF CYS-210 AND CYS-431
    13. 13.
      "Amino-acid transport by heterodimers of 4F2hc/CD98 and members of a permease family."
      Mastroberardino L. , Spindler B. , Pfeiffer R. , Skelly P.J. , Loffing J. , Shoemaker C.B. , Verrey F.
      Nature395:288-291(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    14. 14.
      "Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family."
      Pfeiffer R. , Rossier G. , Spindler B. , Meier C. , Kuehn L.C. , Verrey F.
      EMBO J.18:49-57(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    15. 15.
      "The heterodimeric amino acid transporter 4F2hc/y+LAT2 mediates arginine efflux in exchange with glutamine."
      Broeer A. , Wagner C.A. , Lang F. , Broeer S.
      Biochem. J.349:787-795(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
    16. 16.
      "Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains."
      Broeer A. , Friedrich B. , Wagner C.A. , Fillon S. , Ganapathy V. , Lang F. , Broeer S.
      Biochem. J.355:725-731(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
    17. 17.
      "Role of the System L permease LAT1 in amino acid and iodothyronine transport in placenta."
      Ritchie J.W.A. , Taylor P.M.
      Biochem. J.356:719-725(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    18. 18.
      "Beta1 integrins show specific association with CD98 protein in low density membranes."
      Kolesnikova T.V. , Mannion B.A. , Berditchevski F. , Hemler M.E.
      BMC Biochem.2:10-10(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT;INTERACTION WITH BETA-1 INTEGRINS;MUTAGENESIS OF CYS-210 AND CYS-431
    19. 19.
      "Thyroid hormone transport by the heterodimeric human system L amino acid transporter."
      Friesema E.C.H. , Docter R. , Moerings E.P.C.M. , Verrey F. , Krenning E.P. , Hennemann G. , Visser T.J.
      Endocrinology142:4339-4348(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    20. 20.
      "Expression and regulation of 4F2hc and hLAT1 in human trophoblasts."
      Okamoto Y. , Sakata M. , Ogura K. , Yamamoto T. , Yamaguchi M. , Tasaka K. , Kurachi H. , Tsurudome M. , Murata Y.
      Am. J. Physiol.282:C196-C204(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
    21. 21.
      "Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism."
      He X.H. , Di Y. , Li J. , Xie Y. , Tang Y. , Zhang F. , Wei L. , Zhang Y. , Qin W.X. , Huo K. , Li Y. , Wan D.F. , Gu J.R.
      Biochem. Biophys. Res. Commun.297:528-536(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAM57A/CT120
    22. 22.
      "Transport of a neurotoxicant by molecular mimicry: the methylmercury-L-cysteine complex is a substrate for human L-type large neutral amino acid transporter (LAT) 1 and LAT2."
      Simmons-Willis T.A. , Koh A.S. , Clarkson T.W. , Ballatori N.
      Biochem. J.367:239-246(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    23. 23.
      "Characterization of the system L amino acid transporter in T24 human bladder carcinoma cells."
      Kim D.K. , Kanai Y. , Choi H.W. , Tangtrongsup S. , Chairoungdua A. , Babu E. , Tachampa K. , Anzai N. , Iribe Y. , Endou H.
      Biochim. Biophys. Acta1565:112-121(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION
    24. 24.
      "Cluster analysis of an extensive human breast cancer cell line protein expression map database."
      Harris R.A. , Yang A. , Stein R.C. , Lucy K. , Brusten L. , Herath A. , Parekh R. , Waterfield M.D. , O'Hare M.J. , Neville M.A. , Page M.J. , Zvelebil M.J.
      Proteomics2:212-223(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MASS SPECTROMETRY
      tissue: Mammary cancer.
    25. 25.
      "Nitric oxide synthesis requires activity of the cationic and neutral amino acid transport system y+L in human umbilical vein endothelium."
      Arancibia-Garavilla Y. , Toledo F. , Casanello P. , Sobrevia L.
      Exp. Physiol.88:699-710(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;TISSUE SPECIFICITY
    26. 26.
      "CD98 and intracellular adhesion molecule I regulate the activity of amino acid transporter LAT-2 in polarized intestinal epithelia."
      Liu X. , Charrier L. , Gewirtz A. , Sitaraman S. , Merlin D.
      J. Biol. Chem.278:23672-23677(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;INTERACTION WITH ICAM1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    27. 27.
      "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry."
      Zhang H. , Li X.-J. , Martin D.B. , Aebersold R.
      Nat. Biotechnol.21:660-666(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-365; ASN-381 AND ASN-424
    28. 28.
      "L-type amino acid transporter 1-mediated L-leucine transport at the inner blood-retinal barrier."
      Tomi M. , Mori M. , Tachikawa M. , Katayama K. , Terasaki T. , Hosoya K.
      Invest. Ophthalmol. Vis. Sci.46:2522-2530(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    29. 29.
      "Identification of stereoselective transporters for S-nitroso-L-cysteine: role of LAT1 and LAT2 in biological activity of S-nitrosothiols."
      Li S. , Whorton A.R.
      J. Biol. Chem.280:20102-20110(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT
    30. 30.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-381 AND ASN-424
      tissue: Plasma.
    31. 31.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    32. 32.
      "L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors."
      Nawashiro H. , Otani N. , Shinomiya N. , Fukui S. , Ooigawa H. , Shima K. , Matsuo H. , Kanai Y. , Endou H.
      Int. J. Cancer119:484-492(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    33. 33.
      "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
      Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
      J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
      tissue: Melanoma.
    34. 34.
      "Ecto-phosphorylation of CD98 regulates cell-cell interactions."
      Nguyen H.T.T. , Dalmasso G. , Yan Y. , Obertone T.S. , Sitaraman S.V. , Merlin D.
      PLoS ONE3:E3895-E3895(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-406; SER-408; SER-410; SER-527 AND SER-531
    35. 35.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    36. 36.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-365; ASN-381 AND ASN-506
      tissue: Liver.
    37. 37.
      "A strategy for precise and large scale identification of core fucosylated glycoproteins."
      Jia W. , Lu Z. , Fu Y. , Wang H.P. , Wang L.H. , Chi H. , Yuan Z.F. , Zheng Z.B. , Song L.N. , Han H.H. , Liang Y.M. , Wang J.L. , Cai Y. , Zhang Y.K. , Deng Y.L. , Ying W.T. , He S.M. , Qian X.H.
      Mol. Cell. Proteomics8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-424
    38. 38.
      "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B. , Bausch-Fluck D. , Henderson C. , O'Brien R. , Bibel M. , Schiess R. , Aebersold R. , Watts J.D.
      Nat. Biotechnol.27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-365; ASN-381; ASN-424 AND ASN-506
      tissue: Leukemic T-cell.
    39. 39.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-165;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    40. 40.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    41. 41.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-103 AND SER-134;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    42. 42.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    43. 43.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    44. 44.
      "The structure of human 4F2hc ectodomain provides a model for homodimerization and electrostatic interaction with plasma membrane."
      Fort J. , de la Ballina L.R. , Burghardt H.E. , Ferrer-Costa C. , Turnay J. , Ferrer-Orta C. , Uson I. , Zorzano A. , Fernandez-Recio J. , Orozco M. , Lizarbe M.A. , Fita I. , Palacin M.
      J. Biol. Chem.282:31444-31452(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 212-630;SUBUNIT;MUTAGENESIS OF CYS-210;SUBCELLULAR LOCATION;DISULFIDE BOND
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