SERPINF2 ELISA Kit for Human(Homo sapiens) | EIAab.comSERPINF2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > SERPINF2(Gene name) > Human

SERPINF2 (Gene name),

Alpha-2-antiplasmin (Protein name ), A2AP_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

SERPINF2(AAP;PLI);

Protein name:

Alpha-2-antiplasmin(Alpha-2-AP);

Alternative:

Serpin F2;Alpha-2-plasmin inhibitor(Alpha-2-PI);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

The major targets of this inhibitor are plasmin and trypsin, but it also inactivates chymotrypsin.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

491

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

491:

PGNKDFLQSL | KGFPRGDKLF | GPDLKLVPPM | EEDYPQFGSP | K

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P08697

MIM:

262850

STRING:

9606.ENSP00000321853

String:

P08697

UniGene:

Hs.159509

KEGG:

hsa:5345

Pfam:

PF00079

Uniprot:

P08697

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ELISA Kit for Human Alpha-2-AP

Cat.:

E0160b

Price:

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Manual:

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Packing:

96T

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ELISA Kit for Human Alpha-2-AP

Cat.:

E0160m

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MSDS:

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Packing:

96T

ELISA Kit for Human Alpha-2-AP

Cat.:

E0160h

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Packing:

96T

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CLIA Kit for Human Alpha-2-AP

Cat.:

U0160h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human Alpha-2-AP

Cat.:

U0160m

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MSDS:

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Packing:

96T

CLIA Kit for Human Alpha-2-AP

Cat.:

U0160b

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Packing:

96T

Polyclonal Antibody for Human Alpha-2-AP

Cat.:

P0160Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Alpha-2-AP

Cat.:

P0160Rb-h

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Alpha-2-AP

Monoclonal Antibody for Human Alpha-2-AP

Protein for Human Alpha-2-AP

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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Citations

[1].

"Tissue factor levels and the fibrinolytic system in thin and thick intraluminal thrombus and underlying walls of abdominal aortic aneurysms"

A Siennicka, M Zuchowski, M Kaczmarczyk, et al.

From:Journal of Vascular Surgery

[2].

"Evaluation of Fibrinolytic Inhibitors: Alpha-2-Antiplasmin and Plasminogen Activator Inhibitor 1 in Patients with Obstructive Sleep Apnoea"

Zakrzewski M, Zakrzewska E, Kiciński P, et al.

From:PloS one

References

1.

"Structure of human alpha 2-plasmin inhibitor deduced from the cDNA sequence."
Tone M. , Kikuno R. , Kume-Iwaki A. , Hashimoto-Gotoh T.
J. Biochem.102:1033-1041(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Liver.
2.

"Organization of the human alpha 2-plasmin inhibitor gene."
Hirosawa S. , Nakamura Y. , Miura O. , Sumi Y. , Aoki N.
Proc. Natl. Acad. Sci. U.S.A.85:6836-6840(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING (ISOFORM 1)
3.

Hirosawa S. , Nakamura Y. , Miura O. , Sumi Y. , Aoki N.
Proc. Natl. Acad. Sci. U.S.A.86:1612-1613(1989)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
4.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue: Liver.
5.

"DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
Zody M.C. , Garber M. , Adams D.J. , Sharpe T. , Harrow J. , Lupski J.R. , Nicholson C. , Searle S.M. , Wilming L. , Young S.K. , Abouelleil A. , Allen N.R. , Bi W. , Bloom T. , Borowsky M.L. , Bugalter B.E. , Butler J. , Chang J.L. , more...
Nature440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT VAL-2
7.

"Primary structure of human alpha 2-antiplasmin, a serine protease inhibitor (serpin)."
Holmes W.E. , Nelles L. , Lijnen H.R. , Collen D.
J. Biol. Chem.262:1659-1664(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-491 (ISOFORM 1)
8.

"Different N-terminal forms of alpha 2-plasmin inhibitor in human plasma."
Bangert K. , Johnsen A.H. , Christensen U. , Thorsen S.
Biochem. J.291:623-625(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-58
tissue: Plasma.
9.

"Bovine alpha 2-antiplasmin. N-terminal and reactive site sequence."
Christensen S. , Sottrup-Jensen L.
FEBS Lett.312:100-104(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-52
tissue: Plasma.
10.

"Amino-acid sequence of human alpha 2-antiplasmin."
Lijnen H.R. , Holmes W.E. , van Hoef B. , Wiman B. , Rodriguez H. , Collen D.
Eur. J. Biochem.166:565-574(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 40-491
11.

"Purification and characterization of human antiplasmin, the fast-acting plasmin inhibitor in plasma."
Wiman B. , Collen D.
Eur. J. Biochem.78:19-26(1977) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 40-43
12.

"Structure of the carboxyl-terminal half of human alpha 2-plasmin inhibitor deduced from that of cDNA."
Sumi Y. , Nakamura Y. , Aoki N. , Sakai M. , Muramatsu M.
J. Biochem.100:1399-1402(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 218-491
13.

"Sulfation of a tyrosine residue in the plasmin-binding domain of alpha 2-antiplasmin."
Hortin G. , Fok K.F. , Toren P.C. , Strauss A.W.
J. Biol. Chem.262:3082-3085(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 481-491;SULFATION AT TYR-484
14.

"Alpha-2-antiplasmin: a serpin with two separate but overlapping reactive sites."
Potempa J. , Shieh B.-H. , Travis J.
Science241:699-700(1988) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REACTIVE SITES
15.

"Assignment of a single disulphide bridge in human alpha2-antiplasmin: implications for the structural and functional properties."
Christensen S. , Valnickova Z. , Thogersen I.B. , Olsen E.H. , Enghild J.J.
Biochem. J.323:847-852(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISULFIDE BOND
16.

"A novel plasma proteinase potentiates alpha2-antiplasmin inhibition of fibrin digestion."
Lee K.N. , Jackson K.W. , Christiansen V.J. , Chung K.H. , McKee P.A.
Blood103:3783-3788(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE BY SOLUBLE FAP FORM;CLEAVAGE SITE
17.

"Matriptase-3 is a novel phylogenetically preserved membrane-anchored serine protease with broad serpin reactivity."
Szabo R. , Netzel-Arnett S. , Hobson J.P. , Antalis T.M. , Bugge T.H.
Biochem. J.390:231-242(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN MEMBRANE-ANCHORED SERINE PROTEASE TMPRSS7 INHIBITION;HETERODIMER WITH TMPRSS7
18.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-126; ASN-295 AND ASN-309
tissue: Plasma.
19.

"Antiplasmin-cleaving enzyme is a soluble form of fibroblast activation protein."
Lee K.N. , Jackson K.W. , Christiansen V.J. , Lee C.S. , Chun J.G. , McKee P.A.
Blood107:1397-1404(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE BY PLASMA MEMBRANE AND SOLUBLE FAP FORMS;CLEAVAGE SITE
20.

"Hereditary alpha 2-plasmin inhibitor deficiency caused by a transport-deficient mutation (alpha 2-PI-Okinawa). Deletion of Glu137 by a trinucleotide deletion blocks intracellular transport."
Miura O. , Sugahara Y. , Aoki N.
J. Biol. Chem.264:18213-18219(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT APLID GLU-176 DEL
21.

"A novel missense mutation in the human plasmin inhibitor (alpha2-antiplasmin) gene associated with a bleeding tendency."
Lind B. , Thorsen S.
Br. J. Haematol.107:317-322(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT APLID MET-411;VARIANTS VAL-27; TRP-33 AND LYS-434

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