ACTB ELISA Kit for Human(Homo sapiens) | EIAab.comACTB ELISA Kit for Human(Homo sapiens)

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Index > Protein center > ACTB(Gene name) > Human

ACTB (Gene name),

Actin, cytoplasmic 1 (Protein name ), ACTB_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ACTB;

Protein name:

Actin, cytoplasmic 1;

Alternative:

Beta-actin;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57 SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. Found in a complex with XPO6, Ran, ACTB and PFN1. Component of the MLL5-L complex, at least composed of MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT. Interacts with XPO6 and EMD. Interacts with ERBB2.

Function:

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Subcellular Location:

Cytoplasm cytoskeleton Localized in cytoplasmic mRNP granules containing untranslated mRNAs.

Protein Attributes:

Sequence length:

375

Sequence:

50:

100:

150:

200:

250:

300:

350:

375:

TFQQMWISKQ | EYDESGPSIV | HRKCF

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

MIM:

102630

String:

P60709

KEGG:

hsa:60

UniGene:

Hs.520640

SMR:

P60709

Pfam:

PF00022

Uniprot:

P60709

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ELISA Kit for Human Actin, cytoplasmic 1

Cat.:

E8725h

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96T

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ELISA Kit for Human Actin, cytoplasmic 1

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ELISA Kit for Human Actin, cytoplasmic 1

MSDS:

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ELISA Kit for Human Actin, cytoplasmic 1

Cat.:

E8725m

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96T

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ELISA Kit for Human Actin, cytoplasmic 1

Cat.:

E8725r

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96T

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ELISA Kit for Human Actin, cytoplasmic 1

Cat.:

E8725b

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Packing:

96T

ELISA Kit for Human Actin, cytoplasmic 1

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ELISA Kit for Human Actin, cytoplasmic 1

Cat.:

E8725p

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Packing:

96T

CLIA Kit for Human Actin, cytoplasmic 1

Cat.:

U8725m

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Packing:

96T

CLIA Kit for Human Actin, cytoplasmic 1

Cat.:

U8725p

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Packing:

96T

CLIA Kit for Human Actin, cytoplasmic 1

Cat.:

U8725r

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MSDS:

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Packing:

96T

CLIA Kit for Human Actin, cytoplasmic 1

Cat.:

U8725b

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Packing:

96T

CLIA Kit for Human Actin, cytoplasmic 1

MSDS:

Please sign in first.

CLIA Kit for Human Actin, cytoplasmic 1

MSDS:

Please sign in first.

CLIA Kit for Human Actin, cytoplasmic 1

MSDS:

Please sign in first.

CLIA Kit for Human Actin, cytoplasmic 1

Cat.:

U8725h

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Looking for manual.

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96T

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Polyclonal Antibody for Human Actin, cytoplasmic 1

Cat.:

P8725Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Actin, cytoplasmic 1

Cat.:

P8725Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Actin, cytoplasmic 1

Monoclonal Antibody for Human Actin, cytoplasmic 1

Protein for Human Actin, cytoplasmic 1

Cat.:

R8725h

Price:

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Packing:

1mg

Purity:

>90%

Protein for Human Actin, cytoplasmic 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

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"The DNA sequence of human chromosome 7."
Hillier L.W. , Fulton R.S. , Fulton L.A. , Graves T.A. , Pepin K.H. , Wagner-McPherson C. , Layman D. , Maas J. , Jaeger S. , Walker R. , Wylie K. , Sekhon M. , Becker M.C. , O'Laughlin M.D. , Schaller M.E. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , more...
Nature424:157-164(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
2.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Brain.
tissue: Eye.
tissue: Kidney.
tissue: Muscle.
tissue: Pancreas.
tissue: Placenta.
tissue: Skin.
3.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-28
tissue: Platelet.
4.

Bienvenut W.V.
Submitted (2005-06) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-18; 29-37; 40-50; 85-95; 148-177; 184-191; 197-206; 292-312 AND 316-326;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ASP-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: B-cell lymphoma.
5.

Lubec G. , Afjehi-Sadat L. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-62; 85-113; 184-191; 197-206; 216-254; 291-312; 316-326 AND 360-372;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
6.

"Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions."
Hanukoglu I. , Tanese N. , Fuchs E.
J. Mol. Biol.163:673-678(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 252-375
7.

"Exportin 6: a novel nuclear export receptor that is specific for profilin.actin complexes."
Stueven T. , Hartmann E. , Goerlich D.
EMBO J.22:5928-5940(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH RAN; XPO6 AND PFN1;INTERACTION WITH XPO6
8.

"Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane."
Holaska J.M. , Kowalski A.K. , Wilson K.L.
PLoS Biol.2:1354-1362(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EMD
9.

"Proteomic identification of proteins conjugated to ISG15 in mouse and human cells."
Giannakopoulos N.V. , Luo J.K. , Papov V. , Zou W. , Lenschow D.J. , Jacobs B.S. , Borden E.C. , Li J. , Virgin H.W. , Zhang D.E.
Biochem. Biophys. Res. Commun.336:496-506(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ISGYLATION
10.

"HGAL, a lymphoma prognostic biomarker, interacts with the cytoskeleton and mediates the effects of IL-6 on cell migration."
Lu X. , Chen J. , Malumbres R. , Cubedo Gil E. , Helfman D.M. , Lossos I.S.
Blood110:4268-4277(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GCSAM
11.

"Molecular composition of IMP1 ribonucleoprotein granules."
Joeson L. , Vikesaa J. , Krogh A. , Nielsen L.K. , Hansen T. , Borup R. , Johnsen A.H. , Christiansen J. , Nielsen F.C.
Mol. Cell. Proteomics6:798-811(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A MRNP GRANULE COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY;SUBCELLULAR LOCATION
12.

"Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex."
Lange M. , Kaynak B. , Forster U.B. , Toenjes M. , Fischer J.J. , Grimm C. , Schlesinger J. , Just S. , Dunkel I. , Krueger T. , Mebus S. , Lehrach H. , Lurz R. , Gobom J. , Rottbauer W. , Abdelilah-Seyfried S. , Sperling S.
Genes Dev.22:2370-2384(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE BAF COMPLEX;IDENTIFICATION BY MASS SPECTROMETRY
13.

"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ASP-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
14.

"Nuclear ErbB2 enhances translation and cell growth by activating transcription of ribosomal RNA genes."
Li L.Y. , Chen H. , Hsieh Y.H. , Wang Y.N. , Chu H.J. , Chen Y.H. , Chen H.Y. , Chien P.J. , Ma H.T. , Tsai H.C. , Lai C.C. , Sher Y.P. , Lien H.C. , Tsai C.H. , Hung M.C.
Cancer Res.71:4269-4279(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ERBB2
15.

"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."
Van Damme P. , Lasa M. , Polevoda B. , Gazquez C. , Elosegui-Artola A. , Kim D.S. , De Juan-Pardo E. , Demeyer K. , Hole K. , Larrea E. , Timmerman E. , Prieto J. , Arnesen T. , Sherman F. , Gevaert K. , Aldabe R.
Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND ASP-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia."
Procaccio V. , Salazar G. , Ono S. , Styers M.L. , Gearing M. , Davila A. , Jimenez R. , Juncos J. , Gutekunst C.-A. , Meroni G. , Fontanella B. , Sontag E. , Sontag J.-M. , Faundez V. , Wainer B.H.
Am. J. Hum. Genet.78:947-960(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT DYTJ TRP-183;CHARACTERIZATION OF VARIANT DYTJ TRP-183
17.

"Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA."
Ponte P. , Ng S.Y. , Engel J. , Gunning P. , Kedes L.
Nucleic Acids Res.12:1687-1696(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
18.

"Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns."
Nakajima-Iijima S. , Hamada H. , Reddy P. , Kakunaga T.
Proc. Natl. Acad. Sci. U.S.A.82:6133-6137(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
19.

"Direct proof that the primary site of action of cytochalasin on cell motility processes is actin."
Ohmori H. , Toyama S. , Toyama S.
J. Cell Biol.116:933-941(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
20.

NIEHS SNPs program
Submitted (2004-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
21.

"GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis."
Fujiki R. , Chikanishi T. , Hashiba W. , Ito H. , Takada I. , Roeder R.G. , Kitagawa H. , Kato S.
Nature459:455-459(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN THE MLL5-L COMPLEX
22.

"ALKBH4-dependent demethylation of actin regulates actomyosin dynamics."
Li M.M. , Nilsen A. , Shi Y. , Fusser M. , Ding Y.H. , Fu Y. , Liu B. , Niu Y. , Wu Y.S. , Huang C.M. , Olofsson M. , Jin K.X. , Lv Y. , Xu X.Z. , He C. , Dong M.Q. , Rendtlew Danielsen J.M. , Klungland A. , more...
Nat. Commun.4:1832-1832(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: METHYLATION AT LYS-84;DEMETHYLATION BY ALKBH4
23.

"De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome."
Riviere J.B. , van Bon B.W. , Hoischen A. , Kholmanskikh S.S. , O'Roak B.J. , Gilissen C. , Gijsen S. , Sullivan C.T. , Christian S.L. , Abdul-Rahman O.A. , Atkin J.F. , Chassaing N. , Drouin-Garraud V. , Fry A.E. , Fryns J.P. , Gripp K.W. , Kempers M. , Kleefstra T. , more...
Nat. Genet.44:440-444(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BRWS1 ASP-12; VAL-65; CYS-196 AND HIS-196

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