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Index > Protein center > Actn1(Gene name) > Mouse
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  • Actn1 (Gene name),
  • Alpha-actinin-1 (Protein name ),  ACTN1_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    Actn1;
    Protein name:
    Alpha-actinin-1;
    Alternative:
    F-actin cross-linking protein;Alpha-actinin cytoskeletal isoform;Non-muscle alpha-actinin-1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; antiparallel. Interacts with DDN, MYOZ2, PDLIM2, TTID and LPP (By similarity). Interacts with PSD.
    Function:
    F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
    Subcellular Location:
    Cytoplasm cytoskeleton Cytoplasm myofibril sarcomere Z line Cell membrane Cell projection ruffle Colocalizes with MYOZ2 and PPP3CA at the Z-line of heart and skeletal muscle. Colocalizes with PSD in membrane ruffles and central reticular structures.
    Protein Attributes:
    Sequence length:
    892
    Sequence:
    50:
    MDHYDSQQTN | DYMQPEEDWD | RDLLLDPAWE | KQQRKTFTAW | CNSHLRKAGT | 
    100:
    QIENIEEDFR | DGLKLMLLLE | VISGERLAKP | ERGKMRVHKI | SNVNKALDFI | 
    150:
    ASKGVKLVSI | GAEEIVDGNV | KMTLGMIWTI | ILRFAIQDIS | VEETSAKEGL | 
    200:
    LLWCQRKTAP | YKNVNIQNFH | ISWKDGLGFC | ALIHRHRPEL | IDYGKLRKDD | 
    250:
    PLTNLNTAFD | VAERFLDIPK | MLDAEDIVGT | ARPDEKAIMT | YVSSFYHAFS | 
    300:
    GAQKAETAAN | RICKVLAVNQ | ENEQLMEDYE | KLASDLLEWI | RRTIPWLENR | 
    350:
    VPENTMHAMQ | QKLEDFRDYR | RLHKPPKVQE | KCQLEINFNT | LQTKLRLSNR | 
    400:
    PAFMPSEGRM | VSDINNAWGC | LEQAEKGYEE | WLLNEIRRLE | RLDHLAEKFR | 
    450:
    QKASIHEAWT | DGKEAMLRQK | DYETATLSEI | KALLKKHEAF | ESDLAAHQDR | 
    500:
    VEQIAAIAQE | LNELDYYDSP | SVNARCQKIC | DQWDNLGALT | QKRREALERT | 
    550:
    EKLLETIDQL | YLEYAKRAAP | FNNWMEGAME | DLQDTFIVHT | IEEIQGLTTA | 
    600:
    HEQFKATLPD | ADKERLAILG | IHNEVSKIVQ | TYHVNMAGTN | PYTTITPQEI | 
    650:
    NGKWDHVRQL | VPRRDQALTE | EHARQQHNER | LRKQFGAQAN | VIGPWIQTKM | 
    700:
    EEIGRISIEM | HGTLEDQLSH | LRQYEKSIVN | YKPKIDQLEC | DHQLIQEALI | 
    750:
    FDNKHTNYNM | EHIRVGWEQL | LTTIARTINE | VENQILTRDA | KGISQEQMNE | 
    800:
    FRASFNHFDR | DHSGTLGPEE | FKACLISLGY | DIGNDPQGEA | EFARIMSIVD | 
    850:
    PNRLGVVTFQ | AFIDFMSRET | ADTDTADQVM | ASFKILAGDK | NYITEDELRR | 
    892:
    ELPPDQAEYC | IARMAPYAGP | DSVPGALDYM | SFSTALYGES | DL
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Alpha-actinin-1
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    E0376h
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    ELISA Kit for Mouse Alpha-actinin-1
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    ELISA Kit for Mouse Alpha-actinin-1
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    E0376b
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    96T
    ELISA Kit for Mouse Alpha-actinin-1
    Cat.:
    E0376m
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-actinin-1
    Cat.:
    U0376c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse Alpha-actinin-1
    Cat.:
    U0376h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-actinin-1
    Cat.:
    U0376m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-actinin-1
    Cat.:
    U0376r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Alpha-actinin-1
    Cat.:
    U0376b
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Mouse Alpha-actinin-1
    Cat.:
    P0376Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-actinin-1
    Polyclonal Antibody for Mouse Alpha-actinin-1
    Cat.:
    P0376Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Alpha-actinin-1
    Polyclonal Antibody for Mouse Alpha-actinin-1
    Cat.:
    P0376Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Alpha-actinin-1
    Monoclonal Antibody for Mouse Alpha-actinin-1
    Monoclonal Antibody for Mouse Alpha-actinin-1
    Monoclonal Antibody for Mouse Alpha-actinin-1
    Monoclonal Antibody for Mouse Alpha-actinin-1
    Protein for Mouse Alpha-actinin-1
    Protein for Mouse Alpha-actinin-1
    Protein for Mouse Alpha-actinin-1
    Protein for Mouse Alpha-actinin-1
    Protein for Mouse Alpha-actinin-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Olfactory epithelium.
    2. 2.
      "Calsarcins, a novel family of sarcomeric calcineurin-binding proteins."
      Frey N. , Richardson J.A. , Olson E.N.
      Proc. Natl. Acad. Sci. U.S.A.97:14632-14637(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    3. 3.
      "Somatodendritic localization of EFA6A, a guanine nucleotide exchange factor for ADP-ribosylation factor 6, and its possible interaction with alpha-actinin in dendritic spines."
      Sakagami H. , Honma T. , Sukegawa J. , Owada Y. , Yanagisawa T. , Kondo H.
      Eur. J. Neurosci.25:618-628(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PSD;SUBCELLULAR LOCATION
    4. 4.
      "Rab13 small G protein and junctional Rab13-binding protein (JRAB) orchestrate actin cytoskeletal organization during epithelial junctional development."
      Sakane A. , Abdallah A.A. , Nakano K. , Honda K. , Ikeda W. , Nishikawa Y. , Matsumoto M. , Matsushita N. , Kitamura T. , Sasaki T.
      J. Biol. Chem.287:42455-42468(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MICALL2;SUBCELLULAR LOCATION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF GLN-32 AND VAL-105
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