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Index > Protein center > SLC25A5(Gene name) > Human
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  • SLC25A5 (Gene name),
  • ADP/ATP translocase 2 (Protein name ),  ADT2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC25A5(ANT2);
    Protein name:
    ADP/ATP translocase 2;
    Alternative:
    ADP,ATP carrier protein, fibroblast isoform;ADP,ATP carrier protein 2;Solute carrier family 25 member 5;Adenine nucleotide translocator 2(ANT 2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. Component of the MMXD complex, which includes CIAO1, ERCC2, FAM96B, MMS19 and SLC25A5. Interacts with HIV-1 Vpr.
    Function:
    Catalyzes the exchange of ADP and ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
    Subcellular Location:
    Mitochondrion inner membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    298
    Sequence:
    50:
    MTDAAVSFAK | DFLAGGVAAA | ISKTAVAPIE | RVKLLLQVQH | ASKQITADKQ | 
    100:
    YKGIIDCVVR | IPKEQGVLSF | WRGNLANVIR | YFPTQALNFA | FKDKYKQIFL | 
    150:
    GGVDKRTQFW | LYFAGNLASG | GAAGATSLCF | VYPLDFARTR | LAADVGKAGA | 
    200:
    EREFRGLGDC | LVKIYKSDGI | KGLYQGFNVS | VQGIIIYRAA | YFGIYDTAKG | 
    250:
    MLPDPKNTHI | VISWMIAQTV | TAVAGLTSYP | FDTVRRRMMM | QSGRKGTDIM | 
    298:
    YTGTLDCWRK | IARDEGGKAF | FKGAWSNVLR | GMGGAFVLVL | YDEIKKYT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    String:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADP/ATP translocase 2
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    E0500m
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    ELISA Kit for Human ADP/ATP translocase 2
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    E0500r
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    ELISA Kit for Human ADP/ATP translocase 2
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    E0500h
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    ELISA Kit for Human ADP/ATP translocase 2
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    E0500b
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    Packing:
    96T
    CLIA Kit for Human ADP/ATP translocase 2
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    U0500h
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    96T
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    CLIA Kit for Human ADP/ATP translocase 2
    Cat.:
    U0500b
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ADP/ATP translocase 2
    Cat.:
    U0500m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human ADP/ATP translocase 2
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    U0500r
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human ADP/ATP translocase 2
    Polyclonal Antibody for Human ADP/ATP translocase 2
    Cat.:
    P0500Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ADP/ATP translocase 2
    Cat.:
    P0500Rb-r
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    40ug/0.2ml
    Polyclonal Antibody for Human ADP/ATP translocase 2
    Cat.:
    P0500Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ADP/ATP translocase 2
    Monoclonal Antibody for Human ADP/ATP translocase 2
    Monoclonal Antibody for Human ADP/ATP translocase 2
    Monoclonal Antibody for Human ADP/ATP translocase 2
    Protein for Human ADP/ATP translocase 2
    Protein for Human ADP/ATP translocase 2
    Protein for Human ADP/ATP translocase 2
    Protein for Human ADP/ATP translocase 2

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    Linearity
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    References
    1. 1.
      "The human fibroblast adenine nucleotide translocator gene. Molecular cloning and sequence."
      Ku D.-H. , Kagan J. , Chen S.-T. , Chang C.-D. , Baserga R. , Wurzel J.
      J. Biol. Chem.265:16060-16063(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-111
      tissue: Placenta.
    2. 2.
      "Molecular cloning of a cDNA for a human ADP/ATP carrier which is growth-regulated."
      Battini R. , Ferrari S. , Kaczmarek L. , Calabretta B. , Chen S.T. , Baserga R.
      J. Biol. Chem.262:4355-4358(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ARG-111
    3. 3.
      "Ordered shotgun sequencing of a 135 kb Xq25 YAC containing ANT2 and four possible genes, including three confirmed by EST matches."
      Chen C.N. , Su Y. , Baybayan P. , Siruno A. , Nagaraja R. , Mazzarella R. , Schlessinger D. , Chen E.
      Nucleic Acids Res.24:4034-4041(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ARG-111
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    5. 5.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT ARG-111
      tissue: Eye.
    7. 7.
      Bienvenut W.V.
      Submitted (2004-10) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-31; 34-43; 64-92; 141-147; 189-199 AND 273-296;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT THR-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: B-cell lymphoma.
    8. 8.
      Bienvenut W.V. , Waridel P. , Quadroni M.
      Submitted (2009-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-23; 32-43; 50-60; 64-92; 81-92; 97-106; 112-138; 172-199; 207-235; 245-259 AND 281-295;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT THR-2;METHYLATION AT LYS-52;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Embryonic kidney.
    9. 9.
      "Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver."
      Houldsworth J. , Attardi G.
      Proc. Natl. Acad. Sci. U.S.A.85:377-381(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 46-297
      tissue: Liver.
    10. 10.
      "Mitochondrial membrane permeabilization by HIV-1 Vpr."
      Deniaud A. , Brenner C. , Kroemer G.
      Mitochondrion4:223-233(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HIV-1 VPR
    11. 11.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 AND THR-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-105 AND LYS-163;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation."
      Ito S. , Tan L.J. , Andoh D. , Narita T. , Seki M. , Hirano Y. , Narita K. , Kuraoka I. , Hiraoka Y. , Tanaka K.
      Mol. Cell39:632-640(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;IDENTIFICATION IN MMXD COMPLEX
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "The first identification of lysine malonylation substrates and its regulatory enzyme."
      Peng C. , Lu Z. , Xie Z. , Cheng Z. , Chen Y. , Tan M. , Luo H. , Zhang Y. , He W. , Yang K. , Zwaans B.M. , Tishkoff D. , Ho L. , Lombard D. , He T.C. , Dai J. , Verdin E. , Ye Y. , more...
      Mol. Cell. Proteomics10:M111.012658.01-M111.012658.12(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MALONYLATION AT LYS-23; LYS-92; LYS-96 AND LYS-147
    16. 16.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT THR-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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