AGRN ELISA Kit for Human(Homo sapiens) | EIAab.comAGRN ELISA Kit for Human(Homo sapiens)

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Index > Protein center > AGRN(Gene name) > Human

AGRN (Gene name),

Agrin (Protein name ), AGRIN_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

AGRN(AGRIN);

Protein name:

Agrin;

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to laminin.

Function:

Component of the basal lamina that causes the aggregation of acetylcholine receptors and acetylcholine-esterase on the surface of muscle fibers of the neuromuscular junction.

Subcellular Location:

Secreted extracellular space extracellular matrix Synaptic basal lamina at the neuromuscular junction.

Protein Attributes:

Sequence length:

2045

Sequence:

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2045:

VGPALPKAYG | TGFVGCLRDV | VVGRHPLHLL | EDAVTKPELR | PCPTP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000368678

SMR:

O00468

MIM:

103320

Pfam:

PF00008

UniGene:

Hs.273330

KEGG:

hsa:375790

String:

O00468

Uniprot:

O00468

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ELISA Kit for Human Agrin

Cat.:

E1303m

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96T

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ELISA Kit for Human Agrin

Cat.:

E1303r

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96T

ELISA Kit for Human Agrin

Cat.:

E1303h

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96T

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ELISA Kit for Human Agrin

Cat.:

E1303c

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96T

CLIA Kit for Human Agrin

Cat.:

U1303r

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MSDS:

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Packing:

96T

CLIA Kit for Human Agrin

Cat.:

U1303c

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Packing:

96T

CLIA Kit for Human Agrin

Cat.:

U1303h

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Looking for manual.

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96T

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CLIA Kit for Human Agrin

Cat.:

U1303m

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96T

Polyclonal Antibody for Human Agrin

Cat.:

P1303Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Agrin

Cat.:

P1303Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Agrin

Cat.:

P1303Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Agrin

Monoclonal Antibody for Human Agrin

Protein for Human Agrin

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Primary structure and high expression of human agrin in basement membranes of adult lung and kidney."
Groffen A.J.A. , Buskens C.A.F. , Van Kuppevelt T.H. , Veerkamp J.H. , Monnens L.A.H. , Van den Heuvel L.P.W.J.
Eur. J. Biochem.254:123-128(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);TISSUE SPECIFICITY
2.

Kato S.
Submitted (2004-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3)
tissue: Retinal pigment epithelium.
3.

"The DNA sequence and biological annotation of human chromosome 1."
Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 1703-1949 (ISOFORM 6)
4.

"Agrin binds to the nerve-muscle basal lamina via laminin."
Denzer A.J. , Brandenberger R. , Gesemann M. , Chiquet M. , Ruegg M.A.
J. Cell Biol.137:671-683(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 20-172;INTERACTION WITH LAMININ
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1558-2045
tissue: Brain.
tissue: Colon.
tissue: Kidney.
6.

"An alternative amino-terminus expressed in the central nervous system converts agrin to a type II transmembrane protein."
Neumann F.R. , Bittcher G. , Annies M. , Schumacher B. , Kroger S. , Ruegg M.A.
Mol. Cell. Neurosci.17:208-225(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF TRANSMEMBRANE ISOFORM (ISOFORM 2)
7.

"Identification of agrinSN isoform and muscle-specific receptor tyrosine kinase (MuSK) in sperm."
Kumar P. , Ferns M.J. , Meizel S.
Biochem. Biophys. Res. Commun.342:522-528(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF TRANSMEMBRANE ISOFORM (ISOFORM 2);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
8.

Kumar P. , Ferns M.J. , Meizel S.
Biochem. Biophys. Res. Commun.344:453-453(2006)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
9.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-135
tissue: Liver.
10.

"Proteomics characterization of extracellular space components in the human aorta."
Didangelos A. , Yin X. , Mandal K. , Baumert M. , Jahangiri M. , Mayr M.
Mol. Cell. Proteomics9:2048-2062(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
11.

"Agrin binds to the N-terminal region of Lrp4 protein and stimulates association between Lrp4 and the first immunoglobulin-like domain in muscle-specific kinase (MuSK)."
Zhang W. , Coldefy A.S. , Hubbard S.R. , Burden S.J.
J. Biol. Chem.286:40624-40630(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH LRP4;FUNCTION
12.

"C-terminal Agrin Fragment as a potential marker for sarcopenia caused by degeneration of the neuromuscular junction."
Drey M. , Sieber C.C. , Bauer J.M. , Uter W. , Dahinden P. , Fariello R.G. , Vrijbloed J.W.
Exp. Gerontol.48:76-80(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: POTENTIAL USAGE AS A BIOMARKER FOR SARCOPENIA
13.

"Identification of an agrin mutation that causes congenital myasthenia and affects synapse function."
Huze C. , Bauche S. , Richard P. , Chevessier F. , Goillot E. , Gaudon K. , Ben Ammar A. , Chaboud A. , Grosjean I. , Lecuyer H.A. , Bernard V. , Rouche A. , Alexandri N. , Kuntzer T. , Fardeau M. , Fournier E. , Brancaccio A. , Ruegg M.A. , more...
Am. J. Hum. Genet.85:155-167(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CMSPPD;VARIANT CMSPPD ARG-1709;VARIANTS LEU-23; ASN-58; ILE-105; MET-267; SER-375; VAL-728; ARG-852; MET-984; PHE-1088; LYS-1118; ARG-1135; LEU-1240; ARG-1341; LEU-1451; THR-1514; HIS-1565; ILE-1666; GLN-1671; PRO-1698; HIS-1734; ASN-1789 AND VAL-2045;FUNCTION;CHARACTERIZATION OF VARIANT CMSPPD ARG-1709
14.

Huze C. , Bauche S. , Richard P. , Chevessier F. , Goillot E. , Gaudon K. , Ben Ammar A. , Chaboud A. , Grosjean I. , Lecuyer H.A. , Bernard V. , Rouche A. , Alexandri N. , Kuntzer T. , Fardeau M. , Fournier E. , Brancaccio A. , Ruegg M.A. , more...
Am. J. Hum. Genet.85:536-536(2009)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
15.

"LG2 agrin mutation causing severe congenital myasthenic syndrome mimics functional characteristics of non-neural (z-) agrin."
Maselli R.A. , Fernandez J.M. , Arredondo J. , Navarro C. , Ngo M. , Beeson D. , Cagney O. , Williams D.C. , Wollmann R.L. , Yarov-Yarovoy V. , Ferns M.J.
Hum. Genet.131:1123-1135(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CMSPPD PHE-1727;INTERACTION WITH DAG1;CHARACTERIZATION OF VARIANT CMSPPD PHE-1727
16.

"Agrin mutations lead to a congenital myasthenic syndrome with distal muscle weakness and atrophy."
Nicole S. , Chaouch A. , Torbergsen T. , Bauche S. , de Bruyckere E. , Fontenille M.J. , Horn M.A. , van Ghelue M. , Loeseth S. , Issop Y. , Cox D. , Mueller J.S. , Evangelista T. , Staalberg E. , Ioos C. , Barois A. , Brochier G. , Sternberg D. , more...
Brain137:2429-2443(2014) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT VAL-745;VARIANTS CMSPPD SER-76; ILE-105 AND ARG-1875;CHARACTERIZATION OF VARIANTS CMSPPD SER-76 AND ILE-105

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