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Index > Protein center > AKAP17A(Gene name) > Human
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  • AKAP17A (Gene name),
  • A-kinase anchor protein 17A (Protein name ),  AK17A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    AKAP17A(CXYorf3;DXYS155E;SFRS17A;XE7);
    Protein name:
    A-kinase anchor protein 17A(AKAP-17A);
    Alternative:
    B-lymphocyte antigen;721P;Protein kinase A-anchoring protein 17A(PRKA17A);Protein XE7;Splicing factor, arginine/serine-rich 17A;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer. Component of the spliceosome. Interacts with ZRANB2 and SFRS1/ASF through its Arg/Ser-rich domain. Interacts with RI and RII subunits of PKA.
    Function:
    Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
    Subcellular Location:
    Nucleus speckle
    Protein Attributes:
    Sequence length:
    695
    Sequence:
    50:
    MAAATIVHDT | SEAVELCPAY | GLYLKPITKM | TISVALPQLK | QPGKSISNWE | 
    100:
    VMERLKGMVQ | NHQFSTLRIS | KSTMDFIRFE | GEVENKSLVK | SFLACLDGKT | 
    150:
    IKLSGFSDIL | KVRAAEFKID | FPTRHDWDSF | FRDAKDMNET | LPGERPDTIH | 
    200:
    LEGLPCKWFA | LKESGSEKPS | EDVLVKVFEK | FGEIRNVDIP | MLDPYREEMT | 
    250:
    GRNFHTFSFG | GHLNFEAYVQ | YREYMGFIQA | MSALRGMKLM | YKGEDGKAVA | 
    300:
    CNIKVSFDST | KHLSDASIKK | RQLERQKLQE | LEQQREEQKR | REKEAEERQR | 
    350:
    AEERKQKELE | ELERERKREE | KLRKREQKQR | DRELRRNQKK | LEKLQAEEQK | 
    400:
    QLQEKIKLEE | RKLLLAQRNL | QSIRLIAELL | SRAKAVKLRE | QEQKEEKLRL | 
    450:
    QQQEERRRLQ | EAELRRVEEE | KERALGLQRK | ERELRERLLS | ILLSKKPDDS | 
    500:
    HTHDELGVAH | ADLLQPVLDI | LQTVSSGCVS | ATTLHPLGGQ | PPAGAPKESP | 
    550:
    AHPEADGAPK | SVNGSVAEEA | PCKEVQSSCR | VVPEDGSPEK | RCPGGVLSCI | 
    600:
    PDNNQQPKGI | PACEQNVSRK | DTRSEQDKCN | REPSKGRGRA | TGDGLADRHK | 
    650:
    RERSRARRAS | SREDGRPRKE | RRPHKKHAYK | DDSPRRRSTS | PDHTRSRRSH | 
    695:
    SKDRHRRERS | RERRGSASRK | HSRHRRRSER | SRSRSPSRHR | STWNR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human AKAP-17A
    Cat.:
    E10782h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AKAP-17A
    Cat.:
    U10782h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AKAP-17A
    Cat.:
    P10782Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human AKAP-17A
    Protein for Human AKAP-17A

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Structure and expression of the human pseudoautosomal gene XE7."
      Ellison J.W. , Ramos C. , Yen P.H. , Shapiro L.J.
      Hum. Mol. Genet.1:691-696(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Cloning and sequencing of a trophoblast-endothelial-activated lymphocyte surface protein: cDNA sequence and genomic structure."
      Voland J.R. , Wyzykowski R.J. , Huang M. , Dutton R.W.
      Proc. Natl. Acad. Sci. U.S.A.89:10425-10429(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Placenta.
    3. 3.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT SER-194
      tissue: Blood.
    5. 5.
      "Large-scale proteomic analysis of the human spliceosome."
      Rappsilber J. , Ryder U. , Lamond A.I. , Mann M.
      Genome Res.12:1231-1245(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A COMPLEX WITH THE SPLICEOSOME;IDENTIFICATION BY MASS SPECTROMETRY
    6. 6.
      "An unappreciated role for RNA surveillance."
      Hillman R.T. , Green R.E. , Brenner S.E.
      Genome Biol.5:R8.1-R8.16(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPLICE ISOFORM(S) THAT ARE POTENTIAL NMD TARGET(S)
    7. 7.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-537;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "XE7: a novel splicing factor that interacts with ASF/SF2 and ZNF265."
      Mangs A.H. , Speirs H.J.L. , Goy C. , Adams D.J. , Markus M.A. , Morris B.J.
      Nucleic Acids Res.34:4976-4986(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH ZRANB2 AND SFRS1
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Splicing factor arginine/serine-rich 17A (SFRS17A) is an A-kinase anchoring protein that targets protein kinase A to splicing factor compartments."
      Jarnaess E. , Stokka A.J. , Kvissel A.K. , Skalhegg B.S. , Torgersen K.M. , Scott J.D. , Carlson C.R. , Tasken K.
      J. Biol. Chem.284:35154-35164(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DOMAIN;MUTAGENESIS OF 438-LEU-LEU-439 AND 445-LYS-LYS-446
    11. 11.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-537 AND SER-633;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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