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Index > Protein center > GPT(Gene name) > Human
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  • GPT (Gene name),
  • Alanine aminotransferase 1 (Protein name ),  ALAT1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    GPT(AAT1;GPT1);
    Protein name:
    Alanine aminotransferase 1(ALT1);
    Alternative:
    Glutamic--alanine transaminase 1;Glutamate pyruvate transaminase 1(GPT 1);Glutamic--pyruvic transaminase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transported from skeletal muscles.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    496
    Sequence:
    50:
    MASSTGDRSQ | AVRHGLRAKV | LTLDGMNPRV | RRVEYAVRGP | IVQRALELEQ | 
    100:
    ELRQGVKKPF | TEVIRANIGD | AQAMGQRPIT | FLRQVLALCV | NPDLLSSPNF | 
    150:
    PDDAKKRAER | ILQACGGHSL | GAYSVSSGIQ | LIREDVARYI | ERRDGGIPAD | 
    200:
    PNNVFLSTGA | SDAIVTVLKL | LVAGEGHTRT | GVLIPIPQYP | LYSATLAELG | 
    250:
    AVQVDYYLDE | ERAWALDVAE | LHRALGQARD | HCRPRALCVI | NPGNPTGQVQ | 
    300:
    TRECIEAVIR | FAFEERLFLL | ADEVYQDNVY | AAGSQFHSFK | KVLMEMGPPY | 
    350:
    AGQQELASFH | STSKGYMGEC | GFRGGYVEVV | NMDAAVQQQM | LKLMSVRLCP | 
    400:
    PVPGQALLDL | VVSPPAPTDP | SFAQFQAEKQ | AVLAELAAKA | KLTEQVFNEA | 
    450:
    PGISCNPVQG | AMYSFPRVQL | PPRAVERAQE | LGLAPDMFFC | LRLLEETGIC | 
    496:
    VVPGSGFGQR | EGTYHFRMTI | LPPLEKLRLL | LEKLSRFHAK | FTLEYS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    String:
    SMR:
    Pfam:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human ALT1
    Cat.:
    E0207p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human ALT1
    Cat.:
    E0207r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human ALT1
    Cat.:
    E0207m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human ALT1
    Cat.:
    E0207h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human ALT1
    Cat.:
    E0207b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALT1
    Cat.:
    U0207b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALT1
    Cat.:
    U0207h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALT1
    Cat.:
    U0207m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ALT1
    Cat.:
    U0207p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human ALT1
    Cat.:
    U0207r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ALT1
    Polyclonal Antibody for Human ALT1
    Cat.:
    P0207Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ALT1
    Cat.:
    P0207Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ALT1
    Polyclonal Antibody for Human ALT1
    Cat.:
    P0207Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ALT1
    Monoclonal Antibody for Human ALT1
    Monoclonal Antibody for Human ALT1
    Monoclonal Antibody for Human ALT1
    Monoclonal Antibody for Human ALT1
    Protein for Human ALT1
    Protein for Human ALT1
    Protein for Human ALT1
    Protein for Human ALT1
    Protein for Human ALT1

    R&D Technical Data
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    References
    1. 1.
      "Human glutamate pyruvate transaminase (GPT): localization to 8q24.3, cDNA and genomic sequences, and polymorphic sites."
      Sohocki M.M. , Sullivan L.S. , Harrison W.R. , Sodergren E.J. , Elder F.F.B. , Weinstock G. , Tanase S. , Daiger S.P.
      Genomics40:247-252(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ASN-14
    2. 2.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ASN-14
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    6. 6.
      "Complete amino acid sequence of human liver cytosolic alanine aminotransferase (GPT) determined by a combination of conventional and mass spectral methods."
      Ishiguro M. , Takio K. , Suzuki M. , Oyama R. , Matsuzawa T. , Titani K.
      Biochemistry30:10451-10457(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-496;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2
      tissue: Liver.
    7. 7.
      "Human mRNA for alanine aminotransferase."
      Funatsu M. , Tanase S. , Nakao J. , Hamada F. , Oka T. , Morino Y.
      Submitted (1996-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 4-496
      tissue: Liver.
    8. 8.
      "cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase."
      Yang R.-Z. , Blaileanu G. , Hansen B.C. , Shuldiner A.R. , Gong D.-W.
      Genomics79:445-450(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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