Amacr ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAmacr ELISA Kit for Rat(Rattus norvegicus)

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Amacr (Gene name),

Alpha-methylacyl-CoA racemase (Protein name ), AMACR_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Amacr;

Protein name:

Alpha-methylacyl-CoA racemase;

Alternative:

2-methylacyl-CoA racemase;2-arylpropionyl-CoA epimerase;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Monomer.

Function:

Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Has a role in drug metabolism as well as probably in lipid metabolism. The 2-arylpropionic acid (2-APA's) derivatives, including ibuprofen, are the most widely used anti-inflammatory analgesic cyclooxygenase inhibitors. The (-)-R-enantiomer, which is inactive in terms of cyclooxygenase inhibition, is epimerized in vivo via this enzyme to the cyclooxygenase-inhibiting (+)-S-enantiomer.

Subcellular Location:

Peroxisome Mitochondrion

Protein Attributes:

Sequence length:

382

Sequence:

50:

100:

150:

200:

250:

300:

350:

382:

VEVLKDYGFS | QEEIHQLHSD | RIIESNKLKA | NL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.2590

KEGG:

rno:25284

Pfam:

PF02515

String:

P70473

Uniprot:

P70473

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ELISA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

E0993h

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96T

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ELISA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

E0993m

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Packing:

96T

ELISA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

E0993r

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Packing:

96T

CLIA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

U0993m

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Packing:

96T

CLIA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

U0993h

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Manual:

Looking for manual.

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96T

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CLIA Kit for Rat Alpha-methylacyl-CoA racemase

Cat.:

U0993r

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96T

Polyclonal Antibody for Rat Alpha-methylacyl-CoA racemase

Cat.:

P0993Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Alpha-methylacyl-CoA racemase

Cat.:

P0993Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat Alpha-methylacyl-CoA racemase

Cat.:

P0993Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat Alpha-methylacyl-CoA racemase

Protein for Rat Alpha-methylacyl-CoA racemase

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and expression of a 2-arylpropionyl-coenzyme A epimerase: a key enzyme in the inversion metabolism of ibuprofen."
Reichel C. , Brugger R. , Bang H. , Geisslinger G. , Brune K.
Mol. Pharmacol.51:576-582(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 11-382
strain: Sprague-Dawley.
tissue: Liver.
2.

"Molecular cloning of cDNA species for rat and mouse liver alpha-methylacyl-CoA racemases."
Schmitz W. , Helander H.M. , Hiltunen J.K. , Conzelmann E.
Biochem. J.326:883-889(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-382
tissue: Liver.
3.

"In mouse alpha-methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes."
Kotti T.J. , Savolainen K. , Helander H.M. , Yagi A. , Novikov D.K. , Kalkkinen N. , Conzelmann E. , Hiltunen J.K. , Schmitz W.
J. Biol. Chem.275:20887-20895(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL NUCLEOTIDE SEQUENCE
4.

"2-arylpropionyl-CoA epimerase: partial peptide sequences and tissue localization."
Reichel C. , Bang H. , Brune K. , Geisslinger G. , Menzel S.
Biochem. Pharmacol.50:1803-1806(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 103-117;TISSUE SPECIFICITY
tissue: Liver.
5.

"Purification and properties of an alpha-methylacyl-CoA racemase from rat liver."
Schmitz W. , Fingerhut R. , Conzelmann E.
Eur. J. Biochem.222:313-323(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
tissue: Liver.

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