Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > AMFR2(Gene name) > Human
  • Add your favorite
  • AMFR2 (Gene name),
  • E3 ubiquitin-protein ligase AMFR (Protein name ),  AMFR2_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    AMFR(RNF45);
    Protein name:
    E3 ubiquitin-protein ligase AMFR;
    Alternative:
    gp78;Autocrine motility factor receptor, isoform 2(AMF receptor, isoform 2);RING finger protein 45;
    Organism:
    AMFR2 (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with UBE2G2/UBC7 through a region distinct from the RING finger. Component of a complex required to couple retrotranslocation, ubiquitination and deglycosylation composed of NGLY1, SAKS1, AMFR, VCP and RAD23B.
    Function:
    E3 ubiquitin-protein ligase which can target both itself and other proteins including CD3D and APOB for proteasomal degradation. Mediates polyubiquitination of CYP3A4. Specific receptor for the autocrine motility factor. Mediates tumor invasion and metastasis. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Promotes ubiquitination of misfolded proteins such as mutant CFTR; proposed to mediate sequential ubiquitination by recognizing already ubiquitin-conjugated substrates and to cooperate with E3 ubiquitin-protein ligase RNF5.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    643
    Sequence:
    50:
    MPLLFLERFP | WPSLRTYTGL | SGLALLGTII | SAYRALSQPE | AGPGEPDQLT | 
    100:
    ASLQPEPPAP | ARPSAGGPRA | RDVAQYLLSD | SLFVWVLVNT | ACCVLMLVAK | 
    150:
    LIQCIVFGPL | RVSERQHLKD | KFWNFIFYKF | IFIFGVLNVQ | TVEEVVMWCL | 
    200:
    WFAGLVFLHL | MVQLCKDRFE | YLSFSPTTPM | SSHGRVLSLL | VAMLLSCCGL | 
    250:
    AAVCSITGYT | HGMHTLAFMA | AESLLVTVRT | AHVILRYVIH | LWDLNHEGTW | 
    300:
    EGKGTYVYYT | DFVMELTLLS | LDLMHHIHML | LFGNIWLSMA | SLVIFMQLRY | 
    350:
    LFHEVQRRIR | RHKNYLRVVG | NMEARFAVAT | PEELAVNNDD | CAICWDSMQA | 
    400:
    ARKLPCGHLF | HNSCLRSWLE | QDTSCPTCRM | SLNIADNNRV | REEHQGENLD | 
    450:
    ENLVPVAAAE | GRPRLNQHNH | FFHFDGSRIA | SWLPSFSVEV | MHTTNILGIT | 
    500:
    QASNSQLNAM | AHQIQEMFPQ | VPYHLVLQDL | QLTRSVEITT | DNILEGRIQV | 
    550:
    PFPTQRSDSI | RPALNSPVER | PSSDQEEGET | SAQTERVPLD | LSPRLEETLD | 
    600:
    FGEVEVEPSE | VEDFEARGSR | FSKSADERQR | MLVQRKDELL | QQARKRFLNK | 
    643:
    SSEDDAASES | FLPSEGASSD | PVTLRRRMLA | AAAERRLQKQ | QTS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human E3 ubiquitin-protein ligase AMFR
    CLIA Kit for Human E3 ubiquitin-protein ligase AMFR
    Polyclonal Antibody for Human E3 ubiquitin-protein ligase AMFR
    Monoclonal Antibody for Human E3 ubiquitin-protein ligase AMFR
    Protein for Human E3 ubiquitin-protein ligase AMFR

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    Product Feedback Wall
    Hot Genes
    ALCAM ACE KSR2 ASPRO C19orf80 Gdf5 Trap1a Atf2
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Asprosin Tumor necrosis TRAP1A vitamin d
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter