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Index > Protein center > AQPEP(Gene name) > Human
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  • AQPEP (Gene name),
  • Aminopeptidase Q (Protein name ),  AMPQ_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    AQPEP(LVRN);
    Protein name:
    Aminopeptidase Q(AP-Q);
    Alternative:
    CHL2 antigen;Laeverin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Metalloprotease which may be important for placentation by regulating biological activity of key peptides at the embryo-maternal interface. On synthetic substrates it shows a marked preference for Leu-4-methylcoumaryl-7-amide (Leu-MCA) over Met-MCA, Arg-LCA and Lys-LCA. Cleaves the N-terminal amino acid of several peptides such as angiotensin-3, kisspeptin-10 and endokinin C.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    990
    Sequence:
    50:
    MGPPSSSGFY | VSRAVALLLA | GLVAALLLAL | AVLAALYGHC | ERVPPSELPG | 
    100:
    LRDLEAESSP | PLRQKPTPTP | KPSSARELAV | TTTPSNWRPP | GPWDQLRLPP | 
    150:
    WLVPLHYDLE | LWPQLRPDEL | PAGSLPFTGR | VNITVRCTVA | TSRLLLHSLF | 
    200:
    QDCERAEVRG | PLSPGTGNAT | VGRVPVDDVW | FALDTEYMVL | ELSEPLKPGS | 
    250:
    SYELQLSFSG | LVKEDLREGL | FLNVYTDQGE | RRALLASQLE | PTFARYVFPC | 
    300:
    FDEPALKATF | NITMIHHPSY | VALSNMPKLG | QSEKEDVNGS | KWTVTTFSTT | 
    350:
    PHMPTYLVAF | VICDYDHVNR | TERGKEIRIW | ARKDAIANGS | ADFALNITGP | 
    400:
    IFSFLEDLFN | ISYSLPKTDI | IALPSFDNHA | MENWGLMIFD | ESGLLLEPKD | 
    450:
    QLTEKKTLIS | YVVSHEIGHQ | WFGNLVTMNW | WNNIWLNEGF | ASYFEFEVIN | 
    500:
    YFNPKLPRNE | IFFSNILHNI | LREDHALVTR | AVAMKVENFK | TSEIQELFDI | 
    550:
    FTYSKGASMA | RMLSCFLNEH | LFVSALKSYL | KTFSYSNAEQ | DDLWRHFQMA | 
    600:
    IDDQSTVILP | ATIKNIMDSW | THQSGFPVIT | LNVSTGVMKQ | EPFYLENIKN | 
    650:
    RTLLTSNDTW | IVPILWIKNG | TTQPLVWLDQ | SSKVFPEMQV | SDSDHDWVIL | 
    700:
    NLNMTGYYRV | NYDKLGWKKL | NQQLEKDPKA | IPVIHRLQLI | DDAFSLSKNN | 
    750:
    YIEIETALEL | TKYLAEEDEI | IVWHTVLVNL | VTRDLVSEVN | IYDIYSLLKR | 
    800:
    YLLKRLNLIW | NIYSTIIREN | VLALQDDYLA | LISLEKLFVT | ACWLGLEDCL | 
    850:
    QLSKELFAKW | VDHPENEIPY | PIKDVVLCYG | IALGSDKEWD | ILLNTYTNTT | 
    900:
    NKEEKIQLAY | AMSCSKDPWI | LNRYMEYAIS | TSPFTSNETN | IIEVVASSEV | 
    950:
    GRYVAKDFLV | NNWQAVSKRY | GTQSLINLIY | TIGRTVTTDL | QIVELQQFFS | 
    990:
    NMLEEHQRIR | VHANLQTIKN | ENLKNKKLSA | RIAAWLRRNT | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    SMR:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human AP-Q
    Cat.:
    E11027h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human AP-Q
    Cat.:
    E11027m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AP-Q
    Cat.:
    U11027h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AP-Q
    Cat.:
    U11027m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AP-Q
    Cat.:
    P11027Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AP-Q
    Monoclonal Antibody for Human AP-Q
    Monoclonal Antibody for Human AP-Q
    Protein for Human AP-Q
    Protein for Human AP-Q

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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Human extravillous trophoblasts express laeverin, a novel protein that belongs to membrane-bound gluzincin metallopeptidases."
      Fujiwara H. , Higuchi T. , Yamada S. , Hirano T. , Sato Y. , Nishioka Y. , Yoshioka S. , Tatsumi K. , Ueda M. , Maeda M. , Fujii S.
      Biochem. Biophys. Res. Commun.313:962-968(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 2-12; 269-277; 590-599; 811-820 AND 838-847;POSSIBLE FUNCTION;TISSUE SPECIFICITY
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 435-990;VARIANT PHE-689
      tissue: Placenta.
    3. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT PHE-689
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 2; 3 AND 4);VARIANT PHE-689
      tissue: Placenta.
      tissue: Testis.
    5. 6.
      "Laeverin/aminopeptidase Q, a novel bestatin-sensitive leucine aminopeptidase belonging to the M1 family of aminopeptidases."
      Maruyama M. , Hattori A. , Goto Y. , Ueda M. , Maeda M. , Fujiwara H. , Tsujimoto M.
      J. Biol. Chem.282:20088-20096(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 65-74;FUNCTION;SUBUNIT;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION;GLYCOSYLATION
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