Language:
  
[Sign in] [Register]   

EIAab logo

Index > Protein center > NAGLU(Gene name) > Human
  • Add your favorite
  • NAGLU (Gene name),
  • Alpha-N-acetylglucosaminidase (Protein name ),  ANAG_HUMAN from NCBI database.
  • top
  • Come back to page head.
  • |
  • General Annotation
  • |
  • Antigen Annotation
  • |
  • 3D
  • |
  • Predicted Eptitope
  • |
  • Vaild Sequence
  • |
  • Related Databases
  • |
  • Feedback
  • Gene name:
    NAGLU(UFHSD1);
    Protein name:
    Alpha-N-acetylglucosaminidase;
    Alternative:
    N-acetyl-alpha-glucosaminidase(NAG);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Monomer and homodimer.
    Function:
    Involved in the degradation of heparan sulfate.
    Subcellular Location:
    Lysosome
    Protein Attributes:
    Sequence length:
    743
    Sequence:
    50:
    MEAVAVAAAV | GVLLLAGAGG | AAGDEAREAA | AVRALVARLL | GPGPAADFSV | 
    100:
    SVERALAAKP | GLDTYSLGGG | GAARVRVRGS | TGVAAAAGLH | RYLRDFCGCH | 
    150:
    VAWSGSQLRL | PRPLPAVPGE | LTEATPNRYR | YYQNVCTQSY | SFVWWDWARW | 
    200:
    EREIDWMALN | GINLALAWSG | QEAIWQRVYL | ALGLTQAEIN | EFFTGPAFLA | 
    250:
    WGRMGNLHTW | DGPLPPSWHI | KQLYLQHRVL | DQMRSFGMTP | VLPAFAGHVP | 
    300:
    EAVTRVFPQV | NVTKMGSWGH | FNCSYSCSFL | LAPEDPIFPI | IGSLFLRELI | 
    350:
    KEFGTDHIYG | ADTFNEMQPP | SSEPSYLAAA | TTAVYEAMTA | VDTEAVWLLQ | 
    400:
    GWLFQHQPQF | WGPAQIRAVL | GAVPRGRLLV | LDLFAESQPV | YTRTASFQGQ | 
    450:
    PFIWCMLHNF | GGNHGLFGAL | EAVNGGPEAA | RLFPNSTMVG | TGMAPEGISQ | 
    500:
    NEVVYSLMAE | LGWRKDPVPD | LAAWVTSFAA | RRYGVSHPDA | GAAWRLLLRS | 
    550:
    VYNCSGEACR | GHNRSPLVRR | PSLQMNTSIW | YNRSDVFEAW | RLLLTSAPSL | 
    600:
    ATSPAFRYDL | LDLTRQAVQE | LVSLYYEEAR | SAYLSKELAS | LLRAGGVLAY | 
    650:
    ELLPALDEVL | ASDSRFLLGS | WLEQARAAAV | SEAEADFYEQ | NSRYQLTLWG | 
    700:
    PEGNILDYAN | KQLAGLVANY | YTPRWRLFLE | ALVDSVAQGI | PFQQHQFDKN | 
    743:
    VFQLEQAFVL | SKQRYPSQPR | GDTVDLAKKI | FLKYYPRWVA | GSW
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    String:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-N-acetylglucosaminidase
    Cat.:
    E0171h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Alpha-N-acetylglucosaminidase
    Cat.:
    U0171h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Alpha-N-acetylglucosaminidase
    Cat.:
    P0171Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Alpha-N-acetylglucosaminidase
    Protein for Human Alpha-N-acetylglucosaminidase

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];VARIANT GLY-737
      tissue: Testis.
    2. 2.
      "Cloning and expression of the gene involved in Sanfilippo B syndrome (mucopolysaccharidosis III B)."
      Weber B. , Blanch L. , Clements P.R. , Scott H.S. , Hopwood J.J.
      Hum. Mol. Genet.5:771-777(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;CHARACTERIZATION;VARIANT GLY-737
    3. 3.
      "Molecular dissection of a cosmid from a gene-rich region in 17q21 and characterization of a candidate gene for alpha-N-acetylglucosaminidase with two cDNA isoforms."
      Zhao Z. , Yazdani A. , Shen Y. , Sun Z.S. , Bailey J. , Caskey C.T. , Lee C.C.
      Mamm. Genome7:686-690(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLY-737
    4. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-737
      tissue: Skin.
    5. 6.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-532
      tissue: Liver.
    6. 7.
      "Genotype-phenotype correspondence in Sanfilippo syndrome type B."
      Zhao H.G. , Aronovich E.L. , Whitley C.B.
      Am. J. Hum. Genet.62:53-63(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B CYS-140; CYS-455; LEU-521; GLY-612; CYS-674 AND HIS-674
    7. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B HIS-92; SER-115; CYS-140; LYS-153; LEU-358; VAL-664 AND ARG-682
    8. 9.
      "Identification of 12 novel mutations in the alpha-N-acetylglucosaminidase gene in 14 patients with Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB)."
      Beesley C.E. , Young E.P. , Vellodi A. , Winchester B.G.
      J. Med. Genet.35:910-914(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B CYS-48; CYS-140; CYS-234; ARG-268; LEU-521; TRP-565; PRO-591 AND LYS-705
    9. 10.
      "Mucopolysaccharidosis type IIIB (Sanfilippo B): identification of 18 novel alpha-N-acetylglucosaminidase gene mutations."
      Bunge S. , Knigge A. , Steglich C. , Kleijer W.J. , van Diggelen O.P. , Beck M. , Gal A.
      J. Med. Genet.36:28-31(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B CYS-79; ARG-100; CYS-140; PHE-142 DEL; LEU-243; PHE-277; PRO-280; ARG-292; LYS-452; TRP-482; ARG-561; GLN-565; HIS-674 AND LYS-705;VARIANT GLY-737
    10. 11.
      "Sanfilippo type B syndrome (mucopolysaccharidosis III B): allelic heterogeneity corresponds to the wide spectrum of clinical phenotypes."
      Weber B. , Guo X.-H. , Kleijer W.J. , van de Kamp J.J.P. , Poorthuis B.J.H.M. , Hopwood J.J.
      Eur. J. Hum. Genet.7:34-44(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B LEU-48; SER-69; PRO-227; ARG-248; ARG-292; PHE-334; SER-410; ARG-414; LEU-521; PRO-560; PRO-565; TRP-565; PHE-617; CYS-643; GLU-650; CYS-674 AND PRO-676;VARIANT GLY-737
    11. 12.
      "Mucopolysaccharidosis type IIIB: characterisation and expression of wild-type and mutant recombinant alpha-N-acetylglucosaminidase and relationship with sanfilippo phenotype in an attenuated patient."
      Yogalingam G. , Weber B. , Meehan J. , Rogers J. , Hopwood J.J.
      Biochim. Biophys. Acta1502:415-425(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MPS3B LEU-48;CHARACTERIZATION OF VARIANT MPS3B LEU-48
    12. 13.
      "Molecular defects in the alpha-N-acetylglucosaminidase gene in Italian Sanfilippo type B patients."
      Tessitore A. , Villani G.R.D. , Di Domenico C. , Filocamo M. , Gatti R. , Di Natale P.
      Hum. Genet.107:568-576(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B PHE-35; ASP-82; CYS-140; CYS-156; CYS-234; ARG-292; GLY-501; TRP-520; TYR-534 AND CYS-649;CHARACTERIZATION OF VARIANTS MPS3B PHE-35; ASP-82; CYS-156; GLY-501; TRP-520; TYR-534 AND CYS-649
    13. 14.
      "Allelic heterogeneity in Spanish patients with Sanfilippo disease type B. Identification of eight new mutations."
      Coll M.J. , Anton C. , Chabas A.
      J. Inherit. Metab. Dis.24:83-84(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B SER-79; CYS-234; GLY-474; TRP-565 AND PHE-658
    14. 15.
      "Sanfilippo syndrome in Turkey: identification of novel mutations in subtypes A and B."
      Emre S. , Terzioglu M. , Tokatli A. , Coskun T. , Ozalp I. , Weber B. , Hopwood J.J.
      Hum. Mutat.19:184-185(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B LYS-153; ARG-248; ILE-437 AND ARG-682
    15. 16.
      "Molecular analysis of the alpha-N-acetylglucosaminidase gene in seven Japanese patients from six unrelated families with mucopolysaccharidosis IIIB (Sanfilippo type B), including two novel mutations."
      Tanaka A. , Kimura M. , Lan H.T.N. , Takaura N. , Yamano T.
      J. Hum. Genet.47:484-487(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B MET-241; LEU-314; TRP-482; PRO-565 AND TRP-565
    16. 17.
      "Identification and characterisation of mutations underlying Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB)."
      Lee-Chen G.J. , Lin S.P. , Lin S.Z. , Chuang C.K. , Hsiao K.T. , Huang C.F. , Lien W.C.
      J. Med. Genet.39:E3-E3(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B CYS-130; ARG-154; CYS-309; GLU-412 AND TRP-565;CHARACTERIZATION OF VARIANTS MPS3B CYS-130; ARG-154; CYS-309; GLU-412 AND TRP-565
    17. 18.
      "Sanfilippo B syndrome: molecular defects in Greek patients."
      Beesley C. , Moraitou M. , Winchester B. , Schulpis K. , Dimitriou E. , Michelakakis H.
      Clin. Genet.65:143-149(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B CYS-140; PRO-242; ARG-292; ARG-414; LYS-446; LYS-452; GLN-482 AND LEU-516;CHARACTERIZATION OF VARIANTS MPS3B PRO-242; ARG-414; LYS-446; GLN-482 AND LEU-516
    18. 19.
      "Sanfilippo type B syndrome: five patients with an R565P homozygous mutation in the alpha-N-acetylglucosaminidase gene from the Okinawa islands in Japan."
      Chinen Y. , Tohma T. , Izumikawa Y. , Uehara H. , Ohta T.
      J. Hum. Genet.50:357-359(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MPS3B PRO-565
    19. 20.
      "Molecular defects in Sanfilippo syndrome type B (mucopolysaccharidosis IIIB)."
      Beesley C.E. , Jackson M. , Young E.P. , Vellodi A. , Winchester B.G.
      J. Inherit. Metab. Dis.28:759-767(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MPS3B TRP-38; GLY-77; CYS-79; CYS-130; PRO-246; CYS-309; CYS-335; ARG-414; LYS-452; TRP-482; TRP-520; LEU-521 AND TRP-565;CHARACTERIZATION OF VARIANTS MPS3B TRP-38; GLY-77 AND CYS-335
    Product Feedback Wall
    Hot Genes
    Atf2 ASPRO ACE ALCAM C19orf80 Trap1a KSR2 Gdf5
    Top Searches
    Ubiquitin-protein ligase Ubiquitin ELISA metalloproteinase Asprosin Tumor necrosis TRAP1A Alpha
    Why choose EIAAB
    Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more
    Further Information
    About us Protein center Bank account Distributors Terms & Conditions Career eiaab.cn

    Copyright & copy www.eiaab.com2006-2016 All Rights Reserved    EIAab         Email:eiaab@eiaab.com

    Twitter