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Index > Protein center > Nppa(Gene name) > Rat
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  • Nppa (Gene name),
  • Natriuretic peptides A (Protein name ),  ANF_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Nppa;
    Protein name:
    Natriuretic peptides A;
    Alternative:
    Prepronatriodilatin;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with NPR1.
    Function:
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilatation. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    152
    Sequence:
    50:
    MGSFSITKGF | FLFLAFWLPG | HIGANPVYSA | VSNTDLMDFK | NLLDHLEEKM | 
    100:
    PVEDEVMPPQ | ALSEQTDEAG | AALSSLSEVP | PWTGEVNPSQ | RDGGALGRGP | 
    150:
    WDPSDRSALL | KSKLRALLAG | PRSLRRSSCF | GGRIDRIGAQ | SGLGCNSFRY | 
    152:
    RR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225d
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    Packing:
    96T
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    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225r
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    Packing:
    96T
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    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225h
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    96T
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    ELISA Kit for Rat Natriuretic peptides A
    MSDS:
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    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225m
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    96T
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    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225p
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    96T
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    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225b
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    Packing:
    96T
    ELISA Kit for Rat Natriuretic peptides A
    Cat.:
    E0225c
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    Packing:
    96T
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225b
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225c
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    96T
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225m
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    96T
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225p
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Natriuretic peptides A
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225h
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Rat Natriuretic peptides A
    Cat.:
    U0225d
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    Packing:
    96T
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    Polyclonal Antibody for Rat Natriuretic peptides A
    Polyclonal Antibody for Rat Natriuretic peptides A
    Cat.:
    P0225Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Natriuretic peptides A
    Polyclonal Antibody for Rat Natriuretic peptides A
    Cat.:
    P0225Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Natriuretic peptides A
    Polyclonal Antibody for Rat Natriuretic peptides A
    Polyclonal Antibody for Rat Natriuretic peptides A
    Cat.:
    P0225Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Monoclonal Antibody for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Cat.:
    R0225h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A
    Protein for Rat Natriuretic peptides A

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and sequence analysis of the cDNA for the rat atrial natriuretic factor precursor."
      Yamanaka M. , Greenberg B. , Johnson L. , Seilhamer J.J. , Brewer M. , Friedemann T. , Miller J. , Atlas S.A. , Laragh J. , Lewicki J. , Fiddes J.C.
      Nature309:719-722(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Structure of rat atrial natriuretic factor precursor deduced from cDNA sequence."
      Maki M. , Takayanagi R. , Misono K.S. , Pandey K.N. , Tibbetts C. , Inagami T.
      Nature309:722-724(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The structure of rat preproatrial natriuretic factor as defined by a complementary DNA clone."
      Seidman C.E. , Duby A.D. , Choi E. , Graham R.M. , Haber E. , Homcy C. , Smith J.A. , Seidman J.G.
      Science225:324-326(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    4. 4.
      "Identification of rat gamma atrial natriuretic polypeptide and characterization of the cDNA encoding its precursor."
      Kangawa K. , Tawaragi Y. , Oikawa S. , Mizuno A. , Sakuragawa Y. , Nakazato H. , Fukuda A. , Minamino N. , Matsuo H.
      Nature312:152-155(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "Molecular cloning and characterization of DNA sequences encoding rat and human atrial natriuretic factors."
      Zivin R.A. , Condra J.H. , Dixon R.A.F. , Seidah N.G. , Chretien M. , Nemer M. , Chamberland M. , Drouin J.
      Proc. Natl. Acad. Sci. U.S.A.81:6325-6329(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The elucidation of the structure of atrial natriuretic factor, a new peptide hormone."
      Flynn T.G.
      Can. J. Physiol. Pharmacol.65:2013-2020(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    8. 8.
      "Identification of atrial natriuretic factor gene transcripts in the central nervous system of the rat."
      Gardner D.G. , Vlasuk G.P. , Baxter J.D. , Fiddes J.C. , Lewicki J.A.
      Proc. Natl. Acad. Sci. U.S.A.84:2175-2179(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 38-152
    9. 9.
      "Purification, sequencing and synthesis of natriuretic and vasoactive rat atrial peptide."
      Atlas S.A. , Kleinert H.D. , Camargo M.J. , Januszewicz A. , Sealey J.E. , Laragh J.H. , Schilling J.W. , Lewicki J.A. , Johnson L.K. , Maack T.
      Nature309:717-719(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 126-150;SYNTHESIS OF 126-149
    10. 10.
      "Purification and sequence analysis of bioactive atrial peptides (atriopeptins)."
      Currie M.G. , Geller D.M. , Cole B.R. , Siegel N.R. , Fok K.F. , Adams S.P. , Eubanks S.R. , Galluppi G.R. , Needleman P.
      Science223:67-69(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 127-149;SYNTHESIS
    11. 11.
      "Amino acid sequence of homologous rat atrial peptides: natriuretic activity of native and synthetic forms."
      Seidah N.G. , Lazure C. , Chretien M. , Thibault G. , Garcia R. , Cantin M. , Genest J. , Nutt R.F. , Brady S.F. , Lyle T.A. , Paleveda W.J. , Colton C.D. , Ciccarone T.M. , Veber D.F.
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      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 118-150
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      "NH2-terminal fragment of rat pro-atrial natriuretic factor in the circulation: identification, radioimmunoassay and half-life."
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      Peptides9:47-53(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-38
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      "Crystal structure of hormone-bound atrial natriuretic peptide receptor extracellular domain: rotation mechanism for transmembrane signal transduction."
      Ogawa H. , Qiu Y. , Ogata C.M. , Misono K.S.
      J. Biol. Chem.279:28625-28631(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.95 ANGSTROMS) OF 129-149 IN COMPLEX WITH NPR1;DISULFIDE BOND
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