Protein name:
Angiopoietin-2 (ANG-2) ;
Alternative:
Organism:
Pig (Sus scrofa).
General Annotation
Function:
Can induce tyrosine phosphorylation of TIE2. Binds to Binds to TIE2 receptor and counteracts blood vessel maturation/stability mediated by angiopoietin-1. Its function may be context-dependent. In the absence of angiogenic inducers, such as VEGF, ANG2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Subcellular Location:
Secreted
Protein Attributes:
50:
MWQLVFFALS | CDLVLAAAYN | NFRKSMDSTG | KRQYQVQHGP | CSYTFLLPET |
100:
DNCRSPSSSY | VSNAVQRDAP | LDYDDSVRRL | QVLENIMENN | TQWLMKLESY |
150:
IQDNMKKEMV | EIQQNAVQNQ | TAVMIEIGTN | LLNQTAEQTR | KLTDVEAQVL |
200:
NQTTRLELQL | LEHSLSTNKL | EKQILDQTSE | INKLQDKNSF | LEKKVLDMED |
250:
KHIVQLQSIK | EEKDQLQVLV | SKQNSIIEEL | EKQLVTATVN | NSVLQKQQHD |
300:
LMETVHNLLT | MISTSNSAKH | SLVAKEEQII | FRDCAEAFKS | GLTTSGTYTL |
350:
TFPNSTEETK | AYCDMETGGG | GWTVIQRRED | GSVDFQRTWK | EYKMGFGSPS |
400:
GEHWLGNEFV | SQVTNQKRYV | LKIHLRDWEG | NEAYSLYEHF | YLSSEEFNYR |
450:
IHLKGLTGTA | GKISSISQPG | NDFSTKDADN | DKCICKCSQM | LTGGWWFDAC |
496:
GPSNLNGMYY | PQRQNTNKFN | GIKWYYWKGS | GYSLKATTMM | IRPADF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Pig
Bovine
Dog
Polyclonal Antibody for Pig ANG-2
Polyclonal Antibody for Pig ANG-2
Polyclonal Antibody for Pig ANG-2
Polyclonal Antibody for Pig ANG-2
Polyclonal Antibody for Pig ANG-2
Polyclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
Monoclonal Antibody for Pig ANG-2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]