Gene name:
AGT (SERPINA8) ;
Protein name:
Angiotensinogen ;
Alternative:
Serpin A8 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
During pregnancy, exists as a disulfide-linked 2:2 heterotetramer with the proform of PRG2 and as a complex (probably a 2:2:2 heterohexamer) with pro-PRG2 and C3dg.
Function:
Angiotensin 1-7 is a ligand for the G-protein coupled receptor MAS1 (By similarity). Has vasodilator and antidiuretic effects (By similarity). Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.
Subcellular Location:
Secreted
Protein Attributes:
50:
MRKRAPQSEM | APAGVSLRAT | ILCLLAWAGL | AAGDRVYIHP | FHLVIHNEST |
100:
CEQLAKANAG | KPKDPTFIPA | PIQAKTSPVD | EKALQDQLVL | VAAKLDTEDK |
150:
LRAAMVGMLA | NFLGFRIYGM | HSELWGVVHG | ATVLSPTAVF | GTLASLYLGA |
200:
LDHTADRLQA | ILGVPWKDKN | CTSRLDAHKV | LSALQAVQGL | LVAQGRADSQ |
250:
AQLLLSTVVG | VFTAPGLHLK | QPFVQGLALY | TPVVLPRSLD | FTELDVAAEK |
300:
IDRFMQAVTG | WKTGCSLMGA | SVDSTLAFNT | YVHFQGKMKG | FSLLAEPQEF |
350:
WVDNSTSVSV | PMLSGMGTFQ | HWSDIQDNFS | VTQVPFTESA | CLLLIQPHYA |
400:
SDLDKVEGLT | FQQNSLNWMK | KLSPRTIHLT | MPQLVLQGSY | DLQDLLAQAE |
450:
LPAILHTELN | LQKLSNDRIR | VGEVLNSIFF | ELEADEREPT | ESTQQLNKPE |
485:
VLEVTLNRPF | LFAVYDQSAT | ALHFLGRVAN | PLSTA
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Chicken
ELISA Kit for Human Angiotensinogen
ELISA Kit for Human Angiotensinogen
ELISA Kit for Human Angiotensinogen
ELISA Kit for Human Angiotensinogen
ELISA Kit for Human Angiotensinogen
CLIA Kit for Human Angiotensinogen
CLIA Kit for Human Angiotensinogen
CLIA Kit for Human Angiotensinogen
CLIA Kit for Human Angiotensinogen
CLIA Kit for Human Angiotensinogen
Polyclonal Antibody for Human Angiotensinogen
Polyclonal Antibody for Human Angiotensinogen
Polyclonal Antibody for Human Angiotensinogen
Polyclonal Antibody for Human Angiotensinogen
Polyclonal Antibody for Human Angiotensinogen
Monoclonal Antibody for Human Angiotensinogen
Monoclonal Antibody for Human Angiotensinogen
Monoclonal Antibody for Human Angiotensinogen
Monoclonal Antibody for Human Angiotensinogen
Monoclonal Antibody for Human Angiotensinogen
Protein for Human Angiotensinogen
Protein for Human Angiotensinogen
Protein for Human Angiotensinogen
Protein for Human Angiotensinogen
Protein for Human Angiotensinogen
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
Padhy G, Gangwar A, Sharma M, et al.
[2].
Padhy G, Gangwar A, Sharma M, et al.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-335
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 1-338
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 32-184
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 34-58
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 34-45;SUBUNIT
tissue :
Serum .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 34-43
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-47; ASN-170; ASN-304 AND ASN-328
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION OF ANGIOTENSIN-3
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION OF ANGIOTENSIN-2
13.
"A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9."
Donoghue M.
,
Hsieh F.
,
Baronas E.
,
Godbout K.
,
Gosselin M.
,
Stagliano N.
,
Donovan M.
,
Woolf B.
,
Robison K.
,
Jeyaseelan R.
,
Breitbart R.E.
,
Acton S.
Circ. Res.87:E1-E9(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CLEAVAGE BY ACE AND ACE2
14.
"Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase."
Vickers C.
,
Hales P.
,
Kaushik V.
,
Dick L.
,
Gavin J.
,
Tang J.
,
Godbout K.
,
Parsons T.
,
Baronas E.
,
Hsieh F.
,
Acton S.
,
Patane M.A.
,
Nichols A.
,
Tummino P.
J. Biol. Chem.277:14838-14843(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CLEAVAGE OF ANGIOTENSIN-1 AND ANGIOTENSIN-2 BY ACE2
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ANGIOTENSIN PEPTIDES METABOLISM
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-47
tissue :
Plasma .
17.
"Mass-spectrometric identification of a novel angiotensin peptide in human plasma."
Jankowski V.
,
Vanholder R.
,
van der Giet M.
,
Tolle M.
,
Karadogan S.
,
Gobom J.
,
Furkert J.
,
Oksche A.
,
Krause E.
,
Tran T.N.
,
Tepel M.
,
Schuchardt M.
,
Schluter H.
,
Wiedon A.
,
Beyermann M.
,
Bader M.
,
Todiras M.
,
Zidek W.
,
Jankowski J.
more...
Arterioscler. Thromb. Vasc. Biol.27:297-302(2007)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DECARBOXYLATION AT ASP-34;FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW ON THE RENIN-ANGIOTENSIN SYSTEM
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-47
tissue :
Liver .
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF ANGIOTENSIN-2
22.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 34-43;STRUCTURE BY NMR OF 34-41
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (4.33 ANGSTROMS) OF 34-485 IN COMPLEX WITH RENIN;DISULFIDE BOND
24.
"Molecular basis of human hypertension: role of angiotensinogen."
Jeunemaitre X.
,
Soubrier F.
,
Kotelevtsev Y.V.
,
Lifton R.P.
,
Williams C.S.
,
Charru A.
,
Hunt S.C.
,
Hopkins P.N.
,
Williams R.R.
,
Lalouel J.-M.
,
Corvol P.
Cell71:169-180(1992)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS MET-207; THR-268 AND CYS-281
25.
"A molecular variant of angiotensinogen associated with preeclampsia."
Ward K.
,
Hata A.
,
Jeunemaitre X.
,
Helin C.
,
Nelson L.
,
Namikawa C.
,
Farrington P.F.
,
Ogasawara M.
,
Suzumori K.
,
Tomoda S.
,
Berrebi S.
,
Sasaki M.
,
Corvol P.
,
Lifton R.P.
,
Lalouel J.-M.
Nat. Genet.4:59-61(1993)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT THR-268
26.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANTS ILE-242; ARG-244 AND CYS-281
27.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT PHE-43
28.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHARACTERIZATION OF VARIANT CYS-281
29.
"Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."
Gribouval O.
,
Gonzales M.
,
Neuhaus T.
,
Aziza J.
,
Bieth E.
,
Laurent N.
,
Bouton J.M.
,
Feuillet F.
,
Makni S.
,
Ben Amar H.
,
Laube G.
,
Delezoide A.-L.
,
Bouvier R.
,
Dijoud F.
,
Ollagnon-Roman E.
,
Roume J.
,
Joubert M.
,
Antignac C.
,
Gubler M.-C.
more...
Nat. Genet.37:964-968(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : VARIANT RTD GLN-375