Gene name:
ANXA1 (ANX1;LPC1) ;
Protein name:
Annexin A1 ;
Alternative:
Annexin-1 ;Annexin I ;Calpactin-2 ;Calpactin II ;Lipocortin I ;Chromobindin-9 ;p35 ;Phospholipase A2 inhibitory protein ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer in placenta (20%); linked by transglutamylation. Interacts with DYSF.
Function:
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
Subcellular Location:
Nucleus
Cytoplasm
Cell projection
cilium
Basolateral cell membrane
Found in the cilium, nucleus and basolateral cell membrane of ciliated cells in the tracheal endothelium (By similarity). Found in the cytoplasm of type II pneumocytes and alveolar macrophages.
Protein Attributes:
50:
MAMVSEFLKQ | AWFIENEEQE | YVQTVKSSKG | GPGSAVSPYP | TFNPSSDVAA |
100:
LHKAIMVKGV | DEATIIDILT | KRNNAQRQQI | KAAYLQETGK | PLDETLKKAL |
150:
TGHLEEVVLA | LLKTPAQFDA | DELRAAMKGL | GTDEDTLIEI | LASRTNKEIR |
200:
DINRVYREEL | KRDLAKDITS | DTSGDFRNAL | LSLAKGDRSE | DFGVNEDLAD |
250:
SDARALYEAG | ERRKGTDVNV | FNTILTTRSY | PQLRRVFQKY | TKYSKHDMNK |
300:
VLDLELKGDI | EKCLTAIVKC | ATSKPAFFAE | KLHQAMKGVG | TRHKALIRIM |
346:
VSRSEIDMND | IKAFYQKMYG | ISLCQAILDE | TKGDYEKILV | ALCGGN
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Rat
Mouse
Rabbit
Chicken
Bovine
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
ELISA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
CLIA Kit for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Polyclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Monoclonal Antibody for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
Protein for Human Annexin A1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Cloning and expression of human lipocortin, a phospholipase A2 inhibitor with potential anti-inflammatory activity."
Wallner B.P.
,
Mattaliano R.J.
,
Hession C.
,
Cate R.L.
,
Tizard R.
,
Sinclair L.K.
,
Foeller C.
,
Chow E.P.
,
Browning J.L.
,
Ramachandran K.L.
,
Pepinsky R.B.
Nature320:77-81(1986)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Cervix .
tissue :
Lung .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PARTIAL PROTEIN SEQUENCE;PHOSPHORYLATION AT TYR-21 BY EGFR AND SER-27 BY PKC
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : DIMERIZATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-5 BY TRPM7
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-239 AND LYS-312;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-37;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 41-113