Protein name:
Membrane primary amine oxidase ;
Alternative:
HPAO ;Copper amine oxidase ;Vascular adhesion protein 1 (VAP-1) ;Semicarbazide-sensitive amine oxidase (SSAO) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer; disulfide-linked. Forms heterodimer with AOC2.
Function:
Cell adhesion protein that participates in lymphocyte recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Has a monoamine oxidase activity. May play a role in adipogenesis.
Subcellular Location:
Membrane
Single-pass type II membrane protein
Protein Attributes:
50:
MNQKTILVLL | ILAVITIFAL | VCVLLVGRGG | DGGEPSQLPH | CPSVSPSAQP |
100:
WTHPGQSQLF | ADLSREELTA | VMRFLTQRLG | PGLVDAAQAR | PSDNCVFSVE |
150:
LQLPPKAAAL | AHLDRGSPPP | AREALAIVFF | GRQPQPNVSE | LVVGPLPHPS |
200:
YMRDVTVERH | GGPLPYHRRP | VLFQEYLDID | QMIFNRELPQ | ASGLLHHCCF |
250:
YKHRGRNLVT | MTTAPRGLQS | GDRATWFGLY | YNISGAGFFL | HHVGLELLVN |
300:
HKALDPARWT | IQKVFYQGRY | YDSLAQLEAQ | FEAGLVNVVL | IPDNGTGGSW |
350:
SLKSPVPPGP | APPLQFYPQG | PRFSVQGSRV | ASSLWTFSFG | LGAFSGPRIF |
400:
DVRFQGERLV | YEISLQEALA | IYGGNSPAAM | TTRYVDGGFG | MGKYTTPLTR |
450:
GVDCPYLATY | VDWHFLLESQ | APKTIRDAFC | VFEQNQGLPL | RRHHSDLYSH |
500:
YFGGLAETVL | VVRSMSTLLN | YDYVWDTVFH | PSGAIEIRFY | ATGYISSAFL |
550:
FGATGKYGNQ | VSEHTLGTVH | THSAHFKVDL | DVAGLENWVW | AEDMVFVPMA |
600:
VPWSPEHQLQ | RLQVTRKLLE | MEEQAAFLVG | SATPRYLYLA | SNHSNKWGHP |
650:
RGYRIQMLSF | AGEPLPQNSS | MARGFSWERY | QLAVTQRKEE | EPSSSSVFNQ |
700:
NDPWAPTVDF | SDFINNETIA | GKDLVAWVTA | GFLHIPHAED | IPNTVTVGNG |
750:
VGFFLRPYNF | FDEDPSFYSA | DSIYFRGDQD | AGACEVNPLA | CLPQAAACAP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
ELISA Kit for Human Membrane primary amine oxidase
ELISA Kit for Human Membrane primary amine oxidase
ELISA Kit for Human Membrane primary amine oxidase
ELISA Kit for Human Membrane primary amine oxidase
CLIA Kit for Human Membrane primary amine oxidase
CLIA Kit for Human Membrane primary amine oxidase
CLIA Kit for Human Membrane primary amine oxidase
CLIA Kit for Human Membrane primary amine oxidase
Polyclonal Antibody for Human Membrane primary amine oxidase
Polyclonal Antibody for Human Membrane primary amine oxidase
Polyclonal Antibody for Human Membrane primary amine oxidase
Polyclonal Antibody for Human Membrane primary amine oxidase
Monoclonal Antibody for Human Membrane primary amine oxidase
Monoclonal Antibody for Human Membrane primary amine oxidase
Monoclonal Antibody for Human Membrane primary amine oxidase
Monoclonal Antibody for Human Membrane primary amine oxidase
Protein for Human Membrane primary amine oxidase
Protein for Human Membrane primary amine oxidase
Protein for Human Membrane primary amine oxidase
Protein for Human Membrane primary amine oxidase
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue :
Placenta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE;FUNCTION;SELF-ASSOCIATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue :
Lung .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;SUBUNIT;ALTERNATIVE SPLICING;TISSUE SPECIFICITY
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
tissue :
Placenta .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-5; TYR-167; THR-371; SER-408; HIS-426; TRP-441; THR-582; SER-700 AND VAL-749
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Nature440:1045-1049(2006)
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
PNS .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 79-90 AND 123-132
tissue :
Adipocyte .
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-592; ASN-618 AND ASN-666
tissue :
Plasma .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;TISSUE SPECIFICITY;INDUCTION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;SUBUNIT;MUTAGENESIS OF MET-211; TYR-394 AND LEU-469
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-137; ASN-294; ASN-592; ASN-618 AND ASN-666
tissue :
Liver .
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Mol. Cell. Proteomics8:913-923(2009)
[
PubMed ]
[
Europe PMC ]
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-592
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.9 ANGSTROMS) IN COMPLEX WITH COPPER AND CALCIUM IONS;DISULFIDE BONDS;TOPAQUINONE AT TYR-471;GLYCOSYLATION AT ASN-137; THR-212; ASN-232; ASN-294; ASN-592; ASN-618 AND ASN-666