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Index > Protein center > AP1M1(Gene name) > Human
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  • AP1M1 (Gene name),
  • AP-1 complex subunit mu-1 (Protein name ),  AP1M1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AP1M1(CLTNM);
    Protein name:
    AP-1 complex subunit mu-1;
    Alternative:
    Clathrin coat-associated protein AP47;Clathrin coat assembly protein AP47;Clathrin assembly protein complex 1 medium chain 1;Adaptor-related protein complex 1 mu-1 subunit;Mu1A-adaptin;Mu-adaptin 1;Golgi adaptor HA1/AP1 adaptin mu-1 subunit;AP-mu chain family member mu1A;Adaptor protein complex AP-1 mu-1 subunit;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3). Interacts with MARCH11 (By similarity). Interacts with HIV-1 Nef. Associates with the AP1(MU)-Nef-MHC-I complex; this complex is required for MHC-I internalization.
    Function:
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    Subcellular Location:
    Golgi apparatus Cytoplasmic vesicle clathrin-coated vesicle membrane Peripheral membrane protein Cytoplasmic side Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
    Protein Attributes:
    Sequence length:
    423
    Sequence:
    50:
    MSASAVYVLD | LKGKVLICRN | YRGDVDMSEV | EHFMPILMEK | EEEGMLSPIL | 
    100:
    AHGGVRFMWI | KHNNLYLVAT | SKKNACVSLV | FSFLYKVVQV | FSEYFKELEE | 
    150:
    ESIRDNFVII | YELLDELMDF | GYPQTTDSKI | LQEYITQEGH | KLETGAPRPP | 
    200:
    ATVTNAVSWR | SEGIKYRKNE | VFLDVIESVN | LLVSANGNVL | RSEIVGSIKM | 
    250:
    RVFLSGMPEL | RLGLNDKVLF | DNTGRGKSKS | VELEDVKFHQ | CVRLSRFEND | 
    300:
    RTISFIPPDG | EFELMSYRLN | THVKPLIWIE | SVIEKHSHSR | IEYMIKAKSQ | 
    350:
    FKRRSTANNV | EIHIPVPNDA | DSPKFKTTVG | SVKWVPENSE | IVWSIKSFPG | 
    400:
    GKEYLMRAHF | GLPSVEAEDK | EGKPPISVKF | EIPYFTTSGI | QVRYLKIIEK | 
    423:
    SGYQALPWVR | YITQNGDYQL | RTQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    E12358h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human AP-1 complex subunit mu-1
    MSDS:
    Please sign in first.
    ELISA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    E12358m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    E12358r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human AP-1 complex subunit mu-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    U12358r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    U12358h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AP-1 complex subunit mu-1
    Cat.:
    U12358m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AP-1 complex subunit mu-1
    Cat.:
    P12358Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AP-1 complex subunit mu-1
    Polyclonal Antibody for Human AP-1 complex subunit mu-1
    Polyclonal Antibody for Human AP-1 complex subunit mu-1
    Monoclonal Antibody for Human AP-1 complex subunit mu-1
    Monoclonal Antibody for Human AP-1 complex subunit mu-1
    Monoclonal Antibody for Human AP-1 complex subunit mu-1
    Monoclonal Antibody for Human AP-1 complex subunit mu-1
    Protein for Human AP-1 complex subunit mu-1
    Protein for Human AP-1 complex subunit mu-1
    Protein for Human AP-1 complex subunit mu-1
    Protein for Human AP-1 complex subunit mu-1

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    References
    1. 1.
      "Human clathrin-associated protein AP47 mRNA."
      Qu X. , Zhai Y. , Zhang C. , Yu Y. , Xing G. , Wei H. , Wu S. , Zhou G. , He F.
      Submitted (2000-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      Zhang H.-T. , Burakoff S.J. , Jin Y.-J.
      Submitted (2005-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: T-cell.
    3. 3.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Uterus.
    5. 5.
      Bienvenut W.V. , Claeys D.
      Submitted (2006-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-12; 41-56; 87-96; 130-160; 202-211; 218-225; 380-393 AND 401-421;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Platelet.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] GLN-303
    9. 9.
      "The tyrosine binding pocket in the adaptor protein 1 (AP-1) mu1 subunit is necessary for Nef to recruit AP-1 to the major histocompatibility complex class I cytoplasmic tail."
      Wonderlich E.R. , Williams M. , Collins K.L.
      J. Biol. Chem.283:3011-3022(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION IN A AP1(MU)-NEF-MHC-I COMPLEX
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