Protein name:
Apelin ;
Alternative:
APJ endogenous ligand ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Endogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
Subcellular Location:
Secreted
Protein Attributes:
50:
MNLRLCVQAL | LLLWLSLTAV | CGGSLMPLPD | GNGLEDGNVR | HLVQPRGSRN |
77:
GPGPWQGGRR | KFRRQRPRLS | HKGPMPF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Bovine
ELISA Kit for Human Apelin
ELISA Kit for Human Apelin
ELISA Kit for Human Apelin
ELISA Kit for Human Apelin
CLIA Kit for Human Apelin
CLIA Kit for Human Apelin
CLIA Kit for Human Apelin
CLIA Kit for Human Apelin
Polyclonal Antibody for Human Apelin
Polyclonal Antibody for Human Apelin
Polyclonal Antibody for Human Apelin
Polyclonal Antibody for Human Apelin
Monoclonal Antibody for Human Apelin
Monoclonal Antibody for Human Apelin
Monoclonal Antibody for Human Apelin
Monoclonal Antibody for Human Apelin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue :
Hypothalamus .
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more...
Nature434:325-337(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .
6.
"Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry."
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J. Virol.74:11972-11976(2000)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION