Protein name:
Aquaporin-1(AQP-1);
Alternative:
Water channel protein for red blood cells and kidney proximal tubule;Aquaporin-CHIP;Delayed early response protein 2(DER2);
Organism:
Mouse (Mus musculus).
General annotation
Sub unit:
Homotetramer (By similarity). Interacts with EPHB2; involved in endolymph production in the inner ear.
Function:
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein attributes
50:
MASEIKKKLF | WRAVVAEFLA | MTLFVFISIG | SALGFNYPLE | RNQTLVQDNV |
100:
KVSLAFGLSI | ATLAQSVGHI | SGAHLNPAVT | LGLLLSCQIS | ILRAVMYIIA |
150:
QCVGAIVATA | ILSGITSSLV | DNSLGRNDLA | HGVNSGQGLG | IEIIGTLQLV |
200:
LCVLATTDRR | RRDLGGSAPL | AIGLSVALGH | LLAIDYTGCG | INPARSFGSA |
250:
VLTRNFSNHW | IFWVGPFIGG | ALAVLIYDFI | LAPRSSDFTD | RMKVWTSGQV |
269:
EEYDLDADDI | NSRVEMKPK

Vaild
Sequence:
Database Reference
Uniprot: