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Index > Protein center > SAG(Gene name) > Human
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  • SAG (Gene name),
  • S-arrestin (Protein name ),  ARRS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SAG;
    Protein name:
    S-arrestin;
    Alternative:
    Retinal S-antigen(S-AG);48 kDa protein;Rod photoreceptor arrestin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase.
    Subcellular Location:
    Protein Attributes:
    Sequence length:
    405
    Sequence:
    50:
    MAASGKTSKS | EPNHVIFKKI | SRDKSVTIYL | GNRDYIDHVS | QVQPVDGVVL | 
    100:
    VDPDLVKGKK | VYVTLTCAFR | YGQEDIDVIG | LTFRRDLYFS | RVQVYPPVGA | 
    150:
    ASTPTKLQES | LLKKLGSNTY | PFLLTFPDYL | PCSVMLQPAP | QDSGKSCGVD | 
    200:
    FEVKAFATDS | TDAEEDKIPK | KSSVRLLIRK | VQHAPLEMGP | QPRAEAAWQF | 
    250:
    FMSDKPLHLA | VSLNKEIYFH | GEPIPVTVTV | TNNTEKTVKK | IKAFVEQVAN | 
    300:
    VVLYSSDYYV | KPVAMEEAQE | KVPPNSTLTK | TLTLLPLLAN | NRERRGIALD | 
    350:
    GKIKHEDTNL | ASSTIIKEGI | DRTVLGILVS | YQIKVKLTVS | GFLGELTSSE | 
    400:
    VATEVPFRLM | HPQPEDPAKE | SYQDANLVFE | EFARHNLKDA | GEAEEGKRDK | 
    405:
    NDVDE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    String:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human S-arrestin
    Cat.:
    E1911m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human S-arrestin
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    E1911h
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    MSDS:
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    96T
    ELISA Kit for Human S-arrestin
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    E1911p
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    MSDS:
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    96T
    ELISA Kit for Human S-arrestin
    Cat.:
    E1911r
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    MSDS:
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    96T
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    ELISA Kit for Human S-arrestin
    Cat.:
    E1911d
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human S-arrestin
    Cat.:
    E1911b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911b
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911d
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human S-arrestin
    Cat.:
    U1911p
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human S-arrestin
    Polyclonal Antibody for Human S-arrestin
    Polyclonal Antibody for Human S-arrestin
    Cat.:
    P1911Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human S-arrestin
    Cat.:
    P1911Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human S-arrestin
    Polyclonal Antibody for Human S-arrestin
    Cat.:
    P1911Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human S-arrestin
    Monoclonal Antibody for Human S-arrestin
    Monoclonal Antibody for Human S-arrestin
    Monoclonal Antibody for Human S-arrestin
    Monoclonal Antibody for Human S-arrestin
    Monoclonal Antibody for Human S-arrestin
    Protein for Human S-arrestin
    Protein for Human S-arrestin
    Protein for Human S-arrestin
    Protein for Human S-arrestin
    Protein for Human S-arrestin
    Protein for Human S-arrestin

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    Linearity
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    References
    1. 1.
      "The sequence of human retinal S-antigen reveals similarities with alpha-transducin."
      Yamaki K. , Tsuda M. , Shinohara T.
      FEBS Lett.234:39-43(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-403
      tissue: Retina.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    3. 3.
      "Defects in the rhodopsin kinase gene in the Oguchi form of stationary night blindness."
      Yamamoto S. , Sippel K.C. , Berson E.L. , Dryja T.P.
      Nat. Genet.15:175-178(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT ALA-403
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Mapping of transcription start sites of human retina expressed genes."
      Roni V. , Carpio R. , Wissinger B.
      BMC Genomics8:42-42(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-133
      tissue: Retina.
    6. 6.
      "A homozygous 1-base pair deletion in the arrestin gene is a frequent cause of Oguchi disease in Japanese."
      Fuchs S. , Nakazawa M. , Maw M. , Tamai M. , Oguchi Y. , Gal A.
      Nat. Genet.10:360-362(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN CSNBO1;VARIANT VAL-76
    7. 7.
      "Arrestin gene mutations in autosomal recessive retinitis pigmentosa."
      Nakazawa M. , Wada Y. , Tamai M.
      Arch. Ophthalmol.116:498-501(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RP47
    8. 8.
      "Robust self-association is a common feature of mammalian visual arrestin-1."
      Kim M. , Hanson S.M. , Vishnivetskiy S.A. , Song X. , Cleghorn W.M. , Hubbell W.L. , Gurevich V.V.
      Biochemistry50:2235-2242(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBUNIT
    9. 9.
      "Evaluation of the human arrestin gene in patients with retinitis pigmentosa and stationary night blindness."
      Sippel K.C. , DeStefano J.D. , Berson E.L. , Dryja T.P.
      Invest. Ophthalmol. Vis. Sci.39:665-670(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS VAL-76; CYS-84; MET-125; LEU-364; ILE-378 AND CYS-384
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