Protein name:
Cyclic AMP-dependent transcription factor ATF-1 (cAMP-dependent transcription factor ATF-1) ;
Alternative:
Protein TREB36 ;Activating transcription factor 1 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds DNA as a dimer. Interacts with HIPK2 and CDK3.
Function:
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MEDSHKSTTS | ETAPQPGSAV | QGAHISHIAQ | QVSSLSESEE | SQDSSDSIGS |
100:
SQKAHGILAR | RPSYRKILKD | LSSEDTRGRK | GDGENSGVSA | AVTSMSVPTP |
150:
IYQTSSGQYI | AIAPNGALQL | ASPGTDGVQG | LQTLTMTNSG | STQQGTTILQ |
200:
YAQTSDGQQI | LVPSNQVVVQ | TASGDMQTYQ | IRTTPSATSL | PQTVVMTSPV |
250:
TLTSQTTKTD | DPQLKREIRL | MKNREAAREC | RRKKKEYVKC | LENRVAVLEN |
271:
QNKTLIEELK | TLKDLYSNKS | V
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Mouse
ELISA Kit for Human cAMP-dependent transcription factor ATF-1
ELISA Kit for Human cAMP-dependent transcription factor ATF-1
ELISA Kit for Human cAMP-dependent transcription factor ATF-1
CLIA Kit for Human cAMP-dependent transcription factor ATF-1
CLIA Kit for Human cAMP-dependent transcription factor ATF-1
CLIA Kit for Human cAMP-dependent transcription factor ATF-1
Polyclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Polyclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Polyclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Monoclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Monoclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Monoclonal Antibody for Human cAMP-dependent transcription factor ATF-1
Protein for Human cAMP-dependent transcription factor ATF-1
Protein for Human cAMP-dependent transcription factor ATF-1
Protein for Human cAMP-dependent transcription factor ATF-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Bone marrow .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 39-271 (ISOFORM 1)
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-63;PHOSPHORYLATION BY CAMK1
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CHROMOSOMAL TRANSLOCATION WITH EWSR1;ASSOCIATION WITH ANGIOMATOID FIBROUS HISTIOCYTOMA
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;PHOSPHORYLATION AT SER-63 BY CDK3;INTERACTION WITH CDK3;MUTAGENESIS OF SER-63
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-198;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-198;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Leukemic T-cell .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION AS REPRESSOR;PHOSPHORYLATION AT SER-198 BY HIPK2;INTERACTION WITH HIPK2
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .