ATM ELISA Kit for Human(Homo sapiens) | EIAab.comATM ELISA Kit for Human(Homo sapiens)

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ATM (Gene name),

Serine-protein kinase ATM (Protein name ), ATM_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ATM;

Protein name:

Serine-protein kinase ATM;

Alternative:

Ataxia telangiectasia mutated(A-T mutated);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Dimers or tetramers in inactive state. On DNA damage, autophosphorylation dissociates ATM into monomers rendering them catalytically active. Binds p53/TP53, ABL1, BRCA1, NBN/nibrin and TERF1. Part of the BRCA1-associated genome surveillance complex (BASC), which contains BRCA1, MSH2, MSH6, MLH1, ATM, BLM, PMS2 and the RAD50-MRE11-NBN protein complex. This association could be a dynamic process changing throughout the cell cycle and within subnuclear domains. Interacts with RAD17; DNA damage promotes the association. Interacts with EEF1E1; the interaction, induced on DNA damage, upregulates TP53. Interacts with DCLRE1C, KAT8, KAT5, OBFC2B, ATMIN and CEP164. Interacts with AP2B1 and AP3B2; the interaction occurs in cytoplasmic vesicles (By similarity). Interacts with TELO2 and TTI1. Interacts with DDX1.

Function:

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and monospecific recognition by the B-cell antigen receptor (BCR) expressed on individual B lymphocytes. After the introduction of DNA breaks by the RAG complex on one immunoglobulin allele, acts by mediating a repositioning of the second allele to pericentromeric heterochromatin, preventing accessibility to the RAG complex and recombination of the second allele. Also involved in signal transduction and cell cycle control. May function as a tumor suppressor. Necessary for activation of ABL1 and SAPK. Phosphorylates p53/TP53, FANCD2, NFKBIA, BRCA1, CTIP, nibrin (NBN), TERF1, RAD9 and DCLRE1C. May play a role in vesicle and/or protein transport. Could play a role in T-cell development, gonad and neurological function. Plays a role in replication-dependent histone mRNA degradation. Binds DNA ends.

Subcellular Location:

Nucleus Cytoplasmic vesicle Primarily nuclear. Found also in endocytic vesicles in association with beta-adaptin.

Protein Attributes:

Sequence length:

3056

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GWKAWV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q13315

Pfam:

PF02259

MIM:

208900

UniGene:

Hs.367437

KEGG:

hsa:472

STRING:

9606.ENSP00000278616

Uniprot:

Q13315

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ELISA Kit for Human Serine-protein kinase ATM

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E1361p

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96T

ELISA Kit for Human Serine-protein kinase ATM

Cat.:

E1361h

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Manual:

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96T

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ELISA Kit for Human Serine-protein kinase ATM

Cat.:

E1361m

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Packing:

96T

CLIA Kit for Human Serine-protein kinase ATM

Cat.:

U1361m

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MSDS:

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Packing:

96T

CLIA Kit for Human Serine-protein kinase ATM

Cat.:

U1361h

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Manual:

Looking for manual.

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96T

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CLIA Kit for Human Serine-protein kinase ATM

Cat.:

U1361p

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96T

Polyclonal Antibody for Human Serine-protein kinase ATM

Cat.:

P1361Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Serine-protein kinase ATM

Cat.:

P1361Rb-m

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Monoclonal Antibody for Human Serine-protein kinase ATM

Protein for Human Serine-protein kinase ATM

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"The complete sequence of the coding region of the ATM gene reveals similarity to cell cycle regulators in different species."
Savitsky K. , Sfez S. , Tagle D.A. , Ziv Y. , Sartiel A. , Collins F.S. , Shiloh Y. , Rotman G.
Hum. Mol. Genet.4:2025-2032(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The ATM gene and susceptibility to breast cancer: analysis of 38 breast tumors reveals no evidence for mutation."
Vorechovsky I. , Rasio D. , Luo L. , Monaco C. , Hammarstroem L. , Webster A.D.B. , Zaloudik J. , Barbanti-Brodano G. , James M.R. , Russo G. , Croce C.M. , Negrini M.
Cancer Res.56:2726-2732(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA];VARIANTS CYS-49; ARG-1054; PHE-1420; ILE-2079 AND ALA-2287
3.

"Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene."
Platzer M. , Rotman G. , Bauer D. , Uziel T. , Savitsky K. , Bar-Shira A. , Gilad S. , Shiloh Y. , Rosenthal A.
Genome Res.7:592-605(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D. , Noguchi H. , Totoki Y. , Toyoda A. , Kuroki Y. , Dewar K. , Lloyd C. , Itoh T. , Takeda T. , Kim D.-W. , She X. , Barlow K.F. , Bloom T. , Bruford E. , Chang J.L. , Cuomo C.A. , Eichler E. , FitzGerald M.G. , more...
Nature440:497-500(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT ASN-1983
5.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

NIEHS SNPs program
Submitted (2003-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-2756
7.

"Mutations revealed by sequencing the 5' half of the gene for ataxia telangiectasia."
Byrd P.J. , McConville C.M. , Cooper P. , Parkhill J. , Stankovic T. , McGuire G.M. , Thick J.A. , Taylor A.M.R.
Hum. Mol. Genet.5:145-149(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1369;VARIANT AT 2546-SER--ILE-2548 DEL
8.

"Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression."
Savitsky K. , Platzer M. , Uziel T. , Gilad S. , Sartiel A. , Rosenthal A. , Elroy-Stein O. , Shiloh Y. , Rotman G.
Nucleic Acids Res.25:1678-1684(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-24
9.

"A single ataxia telangiectasia gene with a product similar to PI-3 kinase."
Savitsky K. , Bar-Shira A. , Gilad S. , Rotman G. , Ziv Y. , Vanagaite L. , Tagle D.A. , Smith S. , Uziel T. , Sfez S. , Ashkenazi M. , Pecker I. , Frydman M. , Harnik R. , Patanjali S.R. , Simmons A. , Clines G.A. , Sartiel A. , more...
Science268:1749-1753(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1332-3056;VARIANTS AT 2427-LEU-ARG-2428 DEL; 2546-SER--ILE-2548 DEL AND SER-2860 DEL
tissue: Fibroblast.
10.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1332-3056
tissue: Brain.
11.

"Genomic organization of the ATM locus involved in ataxia-telangiectasia."
Rasio D. , Negrini M. , Croce C.M.
Cancer Res.55:6053-6057(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1349-3056
12.

"The product of the ATM gene is a 370-kDa nuclear phosphoprotein."
Chen G. , Lee E.Y.-H.P.
J. Biol. Chem.271:33693-33697(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION
13.

"The ataxia-telangiectasia gene product, a constitutively expressed nuclear protein that is not up-regulated following genome damage."
Brown K.D. , Ziv Y. , Sadanandan S.N. , Chessa L. , Collins F.S. , Shiloh Y. , Tagle D.A.
Proc. Natl. Acad. Sci. U.S.A.94:1840-1845(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
14.

"Cellular localisation of the ataxia-telangiectasia (ATM) gene product and discrimination between mutated and normal forms."
Watters D. , Khanna K.K. , Beamish H. , Birrell G. , Spring K. , Kedar P. , Gatei M. , Stenzel D. , Hobson K. , Kozlov S. , Zhang N. , Farrell A. , Ramsay J. , Gatti R.A. , Lavin M.F.
Oncogene14:1911-1921(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;VARIANTS AT 2546-SER--ILE-2548 DEL AND TYR-2824
15.

"ATM gene product phosphorylates I kappa B-alpha."
Jung M. , Kondratyev A. , Lee S.A. , Dimtchev A. , Dritschilo A.
Cancer Res.57:24-27(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY
16.

"Interaction between ATM protein and c-Abl in response to DNA damage."
Shafman T. , Khanna K.K. , Kedar P. , Spring K. , Kozlov S. , Yen T. , Hobson K. , Gatei M. , Zhang N. , Watters D. , Egerton M. , Shiloh Y. , Kharbanda S. , Kufe D. , Lavin M.F.
Nature387:520-523(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ABL1
17.

"Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin."
Sarkaria J.N. , Tibbetts R.S. , Busby E.C. , Kennedy A.P. , Hill D.E. , Abraham R.T.
Cancer Res.58:4375-4382(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
18.

"ATM associates with and phosphorylates p53: mapping the region of interaction."
Khanna K.K. , Keating K.E. , Kozlov S. , Scott S. , Gatei M. , Hobson K. , Taya Y. , Gabrielli B. , Chan D. , Lees-Miller S.P. , Lavin M.F.
Nat. Genet.20:398-400(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TP53;CATALYTIC ACTIVITY
19.

"ATM binds to beta-adaptin in cytoplasmic vesicles."
Lim D.-S. , Kirsch D.G. , Canman C.E. , Ahn J.-H. , Ziv Y. , Newman L.S. , Darnell R.B. , Shiloh Y. , Kastan M.B.
Proc. Natl. Acad. Sci. U.S.A.95:10146-10151(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BETA-ADAPTIN
20.

"Enhanced phosphorylation of p53 by ATM in response to DNA damage."
Banin S. , Moyal L. , Shieh S.-Y. , Taya Y. , Anderson C.W. , Chessa L. , Smorodinsky N.I. , Prives C. , Reiss Y. , Shiloh Y. , Ziv Y.
Science281:1674-1677(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF TP53
21.

"Activation of the ATM kinase by ionizing radiation and phosphorylation of p53."
Canman C.E. , Lim D.-S. , Cimprich K.A. , Taya Y. , Tamai K. , Sakaguchi K. , Appella E. , Kastan M.B. , Siliciano J.D.
Science281:1677-1679(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF TP53;MUTAGENESIS OF ASP-2870 AND ASN-2875
22.

"Purification and DNA binding properties of the ataxia-telangiectasia gene product ATM."
Smith G.C.M. , Cary R.B. , Lakin N.D. , Hann B.C. , Teo S.-H. , Chen D.J. , Jackson S.P.
Proc. Natl. Acad. Sci. U.S.A.96:11134-11139(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DNA-BINDING
23.

"Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks."
Cortez D. , Wang Y. , Qin J. , Elledge S.J.
Science286:1162-1166(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF BRCA1
24.

"BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures."
Wang Y. , Cortez D. , Yazdi P. , Neff N. , Elledge S.J. , Qin J.
Genes Dev.14:927-939(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF ATM AS MEMBER OF BASC
25.

"ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway."
Lim D.-S. , Kim S.-T. , Xu B. , Maser R.S. , Lin J. , Petrini J.H.J. , Kastan M.B.
Nature404:613-617(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF NBN
26.

"ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response."
Wu X. , Ranganathan V. , Weisman D.S. , Heine W.F. , Ciccone D.N. , O'Neill T.B. , Crick K.E. , Pierce K.A. , Lane W.S. , Rathbun G. , Livingston D.M. , Weaver D.T.
Nature405:477-482(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF NBN
27.

"Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response."
Li S. , Ting N.S.Y. , Zheng L. , Chen P.-L. , Ziv Y. , Shiloh Y. , Lee E.Y.-H.P. , Lee W.-H.
Nature406:210-215(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF CTIP
28.

"ATM-dependent phosphorylation of nibrin in response to radiation exposure."
Gatei M. , Young D. , Cerosaletti K.M. , Desai-Mehta A. , Spring K. , Kozlov S. , Lavin M.F. , Gatti R.A. , Concannon P. , Khanna K.K.
Nat. Genet.25:115-119(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF NBN
29.

"Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro."
Matsuoka S. , Rotman G. , Ogawa A. , Shiloh Y. , Tamai K. , Elledge S.J.
Proc. Natl. Acad. Sci. U.S.A.97:10389-10394(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN PHOSPHORYLATION OF CHEK2
30.

"Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks."
Kishi S. , Zhou X.Z. , Ziv Y. , Khoo C. , Hill D.E. , Shiloh Y. , Lu K.P.
J. Biol. Chem.276:29282-29291(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF TERF1
31.

"ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses."
Bao S. , Tibbetts R.S. , Brumbaugh K.M. , Fang Y. , Richardson D.A. , Ali A. , Chen S.M. , Abraham R.T. , Wang X.-F.
Nature411:969-974(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAD17
32.

"Convergence of the Fanconi anemia and ataxia telangiectasia signaling pathways."
Taniguchi T. , Garcia-Higuera I. , Xu B. , Andreassen P.R. , Gregory R.C. , Kim S.-T. , Lane W.S. , Kastan M.B. , D'Andrea A.D.
Cell109:459-472(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION OF FANCD2
33.

"Identification of a novel protein kinase mediating Akt survival signaling to the ATM protein."
Suzuki A. , Kusakai G. , Kishimoto A. , Lu J. , Ogura T. , Lavin M.F. , Esumi H.
J. Biol. Chem.278:48-53(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY NUAK1
34.

"DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation."
Bakkenist C.J. , Kastan M.B.
Nature421:499-506(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-1981;SUBUNIT;FUNCTION;MUTAGENESIS OF SER-1981
35.

"Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation."
Ali A. , Zhang J. , Bao S. , Liu I. , Otterness D. , Dean N.M. , Abraham R.T. , Wang X.F.
Genes Dev.18:249-254(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA DAMAGE RESPONSE;INTERACTION WITH PPP5C
36.

"Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response."
Zhang X. , Succi J. , Feng Z. , Prithivirajsingh S. , Story M.D. , Legerski R.J.
Mol. Cell. Biol.24:9207-9220(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DCLRE1C
37.

"The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR."
Park B.-J. , Kang J.W. , Lee S.W. , Choi S.-J. , Shin Y.K. , Ahn Y.H. , Choi Y.H. , Choi D. , Lee K.S. , Kim S.
Cell120:209-221(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EEF1E1
38.

"ATM-dependent phosphorylation of ATF2 is required for the DNA damage response."
Bhoumik A. , Takahashi S. , Breitweiser W. , Shiloh Y. , Jones N. , Ronai Z.
Mol. Cell18:577-587(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
39.

"Involvement of human MOF in ATM function."
Gupta A. , Sharma G.G. , Young C.S.H. , Agarwal M. , Smith E.R. , Paull T.T. , Lucchesi J.C. , Khanna K.K. , Ludwig T. , Pandita T.K.
Mol. Cell. Biol.25:5292-5305(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH KAT8
40.

"Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1."
Kaygun H. , Marzluff W.F.
Nat. Struct. Mol. Biol.12:794-800(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN HISTONE MRNA DEGRADATION ACTIVITY
41.

"A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM."
Sun Y. , Jiang X. , Chen S. , Fernandes N. , Price B.D.
Proc. Natl. Acad. Sci. U.S.A.102:13182-13187(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HTATIP;PHOSPHORYLATION AT SER-1981;ACETYLATION
42.

"Involvement of novel autophosphorylation sites in ATM activation."
Kozlov S.V. , Graham M.E. , Peng C. , Chen P. , Robinson P.J. , Lavin M.F.
EMBO J.25:3504-3514(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-367; SER-1893 AND SER-1981;FUNCTION;MUTAGENESIS OF SER-367; SER-1893 AND SER-1981;IDENTIFICATION BY MASS SPECTROMETRY
43.

"ATMIN defines an NBS1-independent pathway of ATM signalling."
Kanu N. , Behrens A.
EMBO J.26:2933-2941(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ATMIN
44.

"DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity."
Sun Y. , Xu Y. , Roy K. , Price B.D.
Mol. Cell. Biol.27:8502-8509(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-3016;FUNCTION;MUTAGENESIS OF LYS-3016 AND LYS-3018
45.

"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1981 AND SER-1983;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic kidney.
46.

"Cep164 is a mediator protein required for the maintenance of genomic stability through modulation of MDC1, RPA, and CHK1."
Sivasubramaniam S. , Sun X. , Pan Y.R. , Wang S. , Lee E.Y.
Genes Dev.22:587-600(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CEP164
47.

"Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle."
Daub H. , Olsen J.V. , Bairlein M. , Gnad F. , Oppermann F.S. , Korner R. , Greff Z. , Keri G. , Stemmann O. , Mann M.
Mol. Cell31:438-448(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2996;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
48.

"Single-stranded DNA-binding protein hSSB1 is critical for genomic stability."
Richard D.J. , Bolderson E. , Cubeddu L. , Wadsworth R.I.M. , Savage K. , Sharma G.G. , Nicolette M.L. , Tsvetanov S. , McIlwraith M.J. , Pandita R.K. , Takeda S. , Hay R.T. , Gautier J. , West S.C. , Paull T.T. , Pandita T.K. , White M.F. , Khanna K.K.
Nature453:677-681(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH NABP2
49.

"A role for DEAD box 1 at DNA double-strand breaks."
Li L. , Monckton E.A. , Godbout R.
Mol. Cell. Biol.28:6413-6425(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DDX1
50.

"Large-scale proteomics analysis of the human kinome."
Oppermann F.S. , Gnad F. , Olsen J.V. , Hornberger R. , Greff Z. , Keri G. , Mann M. , Daub H.
Mol. Cell. Proteomics8:1751-1764(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2996;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
51.

"ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage."
Taira N. , Yamamoto H. , Yamaguchi T. , Miki Y. , Yoshida K.
J. Biol. Chem.285:4909-4919(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS DYRK2 KINASE
52.

"A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability."
Hurov K.E. , Cotta-Ramusino C. , Elledge S.J.
Genes Dev.24:1939-1950(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TTI1
53.

"Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes."
Takai H. , Xie Y. , de Lange T. , Pavletich N.P.
Genes Dev.24:2019-2030(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TELO2
54.

"Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly."
Kaizuka T. , Hara T. , Oshiro N. , Kikkawa U. , Yonezawa K. , Takehana K. , Iemura S. , Natsume T. , Mizushima N.
J. Biol. Chem.285:20109-20116(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TELO2 AND TTI1
55.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
56.

"Protein phosphatase 5 is necessary for ATR-mediated DNA repair."
Kang Y. , Cheong H.M. , Lee J.H. , Song P.I. , Lee K.H. , Kim S.Y. , Jun J.Y. , You H.J.
Biochem. Biophys. Res. Commun.404:476-481(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-1981
57.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
58.

"Mutations associated with variant phenotypes in ataxia-telangiectasia."
McConville C.M. , Stankovic T. , Byrd P.J. , McGuire G.M. , Yao Q.-Y. , Lennox G.G. , Taylor A.M.R.
Am. J. Hum. Genet.59:320-330(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT GLY-2424; 2546-SER--ILE-2548 DEL AND CYS-2827
59.

"A high frequency of distinct ATM gene mutations in ataxia-telangiectasia."
Wright J. , Teraoka S. , Onengut S. , Tolun A. , Gatti R.A. , Ochs H.D. , Concannon P.
Am. J. Hum. Genet.59:839-846(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT 2546-SER--ILE-2548 DEL;VARIANT ILE-2438
60.

"ATM mutations in cancer families."
Vorechovsky I. , Luo L. , Lindblom A. , Negrini M. , Webster A.D.B. , Croce C.M. , Hammarstroem L.
Cancer Res.56:4130-4133(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT 705-PHE--PRO-707 AND 2546-SER--ILE-2548 DEL;VARIANTS CYS-49; LEU-858; ARG-1054; PHE-1420 AND ARG-1691
61.

"Exon-scanning mutation analysis of the ATM gene in patients with ataxia-telangiectasia."
Vorechovsky I. , Luo L. , Prudente S. , Chessa L. , Russo G. , Kanariou M. , James M.R. , Negrini M. , Webster A.D.B. , Hammarstroem L.
Eur. J. Hum. Genet.4:352-355(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT 705-PHE--PRO-707;VARIANTS LEU-858 AND ARG-1054
62.

"New mutations in the ataxia telangiectasia gene."
Baumer A. , Bernthaler U. , Wolz W. , Hoehn H. , Schindler D.
Hum. Genet.98:246-249(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT ARG-2867
63.

"Predominance of null mutations in ataxia-telangiectasia."
Gilad S. , Khosravi R. , Shkedy D. , Uziel T. , Ziv Y. , Savitsky K. , Rotman G. , Smith S. , Chessa L. , Jorgensen T.J. , Harnik R. , Frydman M. , Sanal O. , Portnoi S. , Goldwicz Z. , Jaspers N.G.J. , Gatti R.A. , Lenoir G. , more...
Hum. Mol. Genet.5:433-439(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT 2427-LEU-ARG-2428 DEL; 2546-SER--ILE-2548 DEL; SER-2860 DEL AND GLY-2904
64.

"Clustering of missense mutations in the ataxia-telangiectasia gene in a sporadic T-cell leukaemia."
Vorechovsky I. , Luo L. , Dyer M.J.S. , Catovsky D. , Amlot P.L. , Yaxley J.C. , Foroni L. , Hammarstroem L. , Webster A.D.B. , Yuille M.A.R.
Nat. Genet.17:96-99(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPLL THR-1407; HIS-1682; HIS-1910; LYS-2164; SER-2396; GLY-2424; PRO-2442; 2546-SER--ILE-2548 DEL; ALA-2695; ARG-2722; VAL-2725; LEU-2732; LYS-2810 DEL; 2871-ARG-HIS-2872 DELINS SER AND VAL-2890;VARIANTS BNHL VAL-1040; SER-1463 AND CYS-2832
65.

"Biallelic mutations in the ATM gene in T-prolymphocytic leukemia."
Stilgenbauer S. , Schaffner C. , Litterst A. , Liebisch P. , Gilad S. , Bar-Shira A. , James M.R. , Lichter P. , Doehner H.
Nat. Med.3:1155-1159(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPLL GLY-2725; PRO-3006 AND CYS-3008
66.

"Ataxia-telangiectasia: identification and detection of founder-effect mutations in the ATM gene in ethnic populations."
Telatar M. , Teraoka S. , Wang Z. , Chun H.H. , Liang T. , Castellvi-Bel S. , Udar N. , Boerresen-Dale A.-L. , Chessa L. , Bernatowska-Matuszkiewicz E. , Porras O. , Watanabe M. , Junker A. , Concannon P. , Gatti R.A.
Am. J. Hum. Genet.62:86-97(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT CYS-2832
67.

"ATM mutations and phenotypes in ataxia-telangiectasia families in the British Isles: expression of mutant ATM and the risk of leukemia, lymphoma, and breast cancer."
Stankovic T. , Kidd A.M.J. , Sutcliffe A. , McGuire G.M. , Robinson P. , Weber P. , Bedenham T. , Bradwell A.R. , Easton D.F. , Lennox G.G. , Haites N. , Byrd P.J. , Taylor A.M.R.
Am. J. Hum. Genet.62:334-345(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT LEU-292; ASP-768; GLN-1001; ARG-1691; ILE-1743; GLY-2424; 2427-LEU-ARG-2428 DEL; 2546-SER--ILE-2548 DEL; ASP-2554; GLY-2668 AND CYS-2827
68.

"Genotype-phenotype relationships in ataxia-telangiectasia and variants."
Gilad S. , Chessa L. , Khosravi R. , Russell P. , Galanty Y. , Piane M. , Gatti R.A. , Jorgensen T.J. , Shiloh Y. , Bar-Shira A.
Am. J. Hum. Genet.62:551-561(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT 1812-ALA-PHE-1813 DELINS VAL
69.

"Ataxia-telangiectasia without immunodeficiency: novel point mutations within and adjacent to the phosphatidylinositol 3-kinase-like domain."
Toyoshima M. , Hara T. , Zhang H. , Yamamoto T. , Akaboshi S. , Nanba E. , Ohno K. , Hori N. , Sato K. , Takeshita K.
Am. J. Med. Genet.75:141-144(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT PRO-2656
70.

"Inactivation of the ATM gene in T-cell prolymphocytic leukemias."
Stoppa-Lyonnet D. , Soulier J. , Lauge A. , Dastot H. , Garand R. , Sigaux F. , Stern M.-H.
Blood91:3920-3926(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TPLL GLY-2486
71.

"Strategies for mutational analysis of the large multiexon ATM gene using high-density oligonucleotide arrays."
Hacia J.G. , Sun B. , Hunt N. , Edgemon K. , Mosbrook D. , Robbins C. , Fodor S.P.A. , Tagle D.A. , Collins F.S.
Genome Res.8:1245-1258(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT 2855-ARG-ILE-2856 AND CYS-3008;VARIANT VAL-1853
72.

"A double missense mutation in the ATM gene of a Dutch family with ataxia telangiectasia."
van Belzen M.J. , Hiel J.A.P. , Weemaes C.M.R. , Gabreeels F.J.M. , van Engelen B.G.M. , Smeets D.F.C.M. , van den Heuvel L.P.W.J.
Hum. Genet.102:187-191(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT 2625-GLU-PRO-2626
73.

"ATM mutations in patients with ataxia telangiectasia screened by a hierarchical strategy."
Sasaki T. , Tian H. , Kukita Y. , Inazuka M. , Tahira T. , Imai T. , Yamauchi M. , Saito T. , Hori T. , Hashimoto-Tamaoki T. , Komatsu K. , Nikaido O. , Hayashi K.
Hum. Mutat.12:186-195(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT LEU-2829;VARIANTS GLU-126; ASP-514 AND ASN-1853
74.

"ATM germline mutations in classical ataxia-telangiectasia patients in the Dutch population."
Broeks A. , de Klein A. , Floore A.N. , Muijtjens M. , Kleijer W.J. , Jaspers N.G.J. , van 't Veer L.J.
Hum. Mutat.12:330-337(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT ASP-1091 AND ARG-1566;VARIANTS LEU-858 AND ARG-1054
75.

"Ataxia-telangiectasia in the Japanese population: identification of R1917X, W2491R, R2909G, IVS33+2T-->A, and 7883del5, the latter two being relatively common mutations."
Fukao T. , Song X.-Q. , Yoshida T. , Tashita H. , Kaneko H. , Teramoto T. , Inoue R. , Katamura K. , Mayumi M. , Hiratani M. , Taniguchi N. , Arai J. , Wakiguchi H. , Bar-Shira A. , Shiloh Y. , Kondo N.
Hum. Mutat.12:338-343(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT ARG-2491 AND GLY-2909
76.

"ATM is usually rearranged in T-cell prolymphocytic leukaemia."
Yuille M.A.R. , Coignet L.J.A. , Abraham S.M. , Yaqub F. , Luo L. , Matutes E. , Brito-Babapulle V. , Vorechovsky I. , Dyer M.J.S. , Catovsky D.
Oncogene16:789-796(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS TPLL GLY-2139; VAL-2890 AND CYS-3008
77.

Yuille M.A.R. , Coignet L.J.A. , Abraham S.M. , Yaqub F. , Luo L. , Matutes E. , Brito-Babapulle V. , Vorechovsky I. , Dyer M.J.S. , Catovsky D.
Oncogene16:2955-2955(1998)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
78.

"Somatic ATM mutations indicate a pathogenic role of ATM in B-cell chronic lymphocytic leukemia."
Schaffner C. , Stilgenbauer S. , Rappold G.A. , Doehner H. , Lichter P.
Blood94:748-753(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BCLL VAL-1853; ARG-1953; PRO-2420; HIS-3008 AND ASN-3018;VARIANTS MCL LYS-2418 INS AND GLY-2423;VARIANT ASN-1853
79.

"ATM mutations in B-cell chronic lymphocytic leukemia."
Bullrich F. , Rasio D. , Kitada S. , Starostik P. , Kipps T. , Keating M. , Albitar M. , Reed J.C. , Croce C.M.
Cancer Res.59:24-27(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BCLL CYS-332; ARG-1691 AND GLY-2424
80.

"Rapid and efficient ATM mutation detection by fluorescent chemical cleavage of mismatch: identification of four novel mutations."
Izatt L. , Vessey C. , Hodgson S.V. , Solomon E.
Eur. J. Hum. Genet.7:310-320(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT AT PRO-1465
81.

"Identification of germline missense mutations and rare allelic variants in the ATM gene in early-onset breast cancer."
Izatt L. , Greenman J. , Hodgson S.V. , Ellis D. , Watts S. , Scott G. , Jacobs C. , Liebmann R. , Zvelebil M.J. , Mathew C. , Solomon E.
Genes Chromosomes Cancer26:286-294(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CYS-49; LEU-182; PRO-707; LEU-858; PHE-1420; ALA-1570; ASN-1853 AND SER-2765
82.

"Characterization of ATM gene mutations in 66 ataxia telangiectasia families."
Sandoval N. , Platzer M. , Rosenthal A. , Doerk T. , Bendix R. , Skawran B. , Stuhrmann M. , Wegner R.-D. , Sperling K. , Banin S. , Shiloh Y. , Baumer A. , Bernthaler U. , Sennefelder H. , Brohm M. , Weber B.H.F. , Schindler D.
Hum. Mol. Genet.8:69-79(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT SER-570; CYS-785; GLY-1913; GLY-2016; ASP-2067; CYS-2227; ASP-2470; VAL-2662 DEL; PRO-2849 AND ARG-2867;VARIANTS CYS-49; LEU-858; ARG-1054; ASN-1853 AND VAL-1853
83.

"New mutations, polymorphisms, and rare variants in the ATM gene detected by a novel SSCP strategy."
Castellvi-Bel S. , Sheikhavandi S. , Telatar M. , Tai L.-Q. , Hwang M.J. , Wang Z. , Yang Z. , Cheng R. , Gatti R.A.
Hum. Mutat.14:156-162(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT;VARIANTS ASN-1454 AND ASN-1853
84.

"Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia."
Stankovic T. , Weber P. , Stewart G. , Bedenham T. , Murray J. , Byrd P.J. , Moss P.A.H. , Taylor A.M.R.
Lancet353:26-29(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS BCLL THR-350; THR-352; ARG-1054; THR-2274 AND ALA-2695
85.

"Missense mutations at ATM gene and cancer risk."
Vorechovsky I. , Luo L. , Ortmann E. , Steinmann D. , Doerk T.
Lancet353:1276-1276(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARG-1054
86.

Vorechovsky I. , Luo L. , Ortmann E. , Steinmann D. , Doerk T.
Lancet354:780-780(1999)

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
87.

"Mutations at the ataxia-telangiectasia locus and clinical phenotypes of A-T patients."
Li A. , Swift M.
Am. J. Med. Genet.92:170-177(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT GLU-224; VAL-323; PRO-1420; CYS-2218; 2546-SER--ILE-2548 DEL; GLN-2625; CYS-2832; 2855-ARG-ILE-2856 AND CYS-3008;VARIANTS VAL-1853 AND ILE-2438
88.

"Ataxia-telangiectasia: phenotype/genotype studies of ATM protein expression, mutations, and radiosensitivity."
Becker-Catania S.G. , Chen G. , Hwang M.J. , Wang Z. , Sun X. , Sanal O. , Bernatowska-Matuszkiewicz E. , Chessa L. , Lee E.Y.-H.P. , Gatti R.A.
Mol. Genet. Metab.70:122-133(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS AT
89.

"Mantle cell lymphoma is characterized by inactivation of the ATM gene."
Schaffner C. , Idler I. , Stilgenbauer S. , Doehner H. , Lichter P.
Proc. Natl. Acad. Sci. U.S.A.97:2773-2778(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MCL LYS-2418 INS; GLY-2423 AND CYS-3008
90.

"Patterns of somatic mutation in human cancer genomes."
Greenman C. , Stephens P. , Smith R. , Dalgliesh G.L. , Hunter C. , Bignell G. , Davies H. , Teague J. , Butler A. , Stevens C. , Edkins S. , O'Meara S. , Vastrik I. , Schmidt E.E. , Avis T. , Barthorpe S. , Bhamra G. , Buck G. , more...
Nature446:153-158(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] GLN-23; CYS-49; GLU-126; HIS-140; GLN-250; PHE-333; CYS-337; HIS-337; ALA-410; SER-504; ASP-514; TYR-540; VAL-546; LEU-582; PRO-707; GLN-848; LEU-858; SER-872; TRP-924; ALA-935; ARG-1054; PHE-1179; ILE-1321; TYR-1380; SER-1382; PHE-1420; MET-1469; CYS-1475; SER-1650; THR-1739; ASN-1853; VAL-1853; ILE-1916; THR-1945; CYS-1961; ASP-1991; PHE-2307; PRO-2332; PHE-2356; LEU-2408; PRO-2442; GLN-2443; ARG-2464; ARG-2492; ALA-2666; HIS-2719; ARG-2842 AND ASN-2870

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