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Index > Protein center > Bace2(Gene name) > Rat
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  • Bace2 (Gene name),
  • Beta-secretase 2 (Protein name ),  BACE2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Bace2;
    Protein name:
    Beta-secretase 2;
    Alternative:
    Memapsin-1;Beta-site amyloid precursor protein cleaving enzyme 2(Beta-site APP cleaving enzyme 2);Theta-secretase;Membrane-associated aspartic protease 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Monomer. Interacts ith RTN3 and RTN4.
    Function:
    Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.
    Subcellular Location:
    Membrane Single-pass type I membrane protein Golgi apparatus Endoplasmic reticulum Endosome Cell surface
    Protein Attributes:
    Sequence length:
    514
    Sequence:
    50:
    MGALLRALLL | PLLAQWLLRA | VPVLAPAPFT | LPLQVAGAAN | HRASTVPGLG | 
    100:
    TPELPRADGL | ALALEPARAT | ANFLAMVDNL | QGDSGRGYYL | EMLIGTPPQK | 
    150:
    VRILVDTGSS | NFAVAGAPHS | YIDTYFDSES | SSTYHSKGFE | VTVKYTQGSW | 
    200:
    TGFVGEDLVT | IPKGFNSSFL | VNIATIFESE | NFFLPGIKWN | GILGLAYAAL | 
    250:
    AKPSSSLETF | FDSLVAQAKI | PDIFSMQMCG | AGLPVAGSGT | NGGSLVLGGI | 
    300:
    EPSLYKGDIW | YTPIKEEWYY | QIEILKLEIG | GQSLNLDCRE | YNADKAIVDS | 
    350:
    GTTLLRLPQK | VFDAVVEAVA | RTSLIPEFSD | GFWTGAQLAC | WTNSETPWAY | 
    400:
    FPKISIYLRD | ENASRSFRIT | ILPQLYIQPM | MGAGFNYECY | RFGISSSTNA | 
    450:
    LVIGATVMEG | FYVVFDRAQR | RVGFAVSPCA | EIAGTTVSEI | SGPFSTEDIA | 
    500:
    SNCVPAQALN | EPILWIVSYA | LMSVCGAILL | VLILLLLFPL | HCRHAPRDPE | 
    514:
    VVNDESSLVR | HRWK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Beta-secretase 2
    Cat.:
    E1812h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Rat Beta-secretase 2
    Cat.:
    E1812r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Beta-secretase 2
    Cat.:
    E1812m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Beta-secretase 2
    Cat.:
    U1812m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beta-secretase 2
    Cat.:
    U1812r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Beta-secretase 2
    Cat.:
    U1812h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Beta-secretase 2
    Cat.:
    P1812Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Beta-secretase 2
    Cat.:
    P1812Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Beta-secretase 2
    Cat.:
    P1812Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Beta-secretase 2
    Monoclonal Antibody for Rat Beta-secretase 2
    Monoclonal Antibody for Rat Beta-secretase 2
    Protein for Rat Beta-secretase 2
    Protein for Rat Beta-secretase 2
    Protein for Rat Beta-secretase 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Prostate.
    2. 2.
      "A genomic analysis of rat proteases and protease inhibitors."
      Puente X.S. , Lopez-Otin C.
      Genome Res.14:609-622(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
      strain: Sprague-Dawley.
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