TGFBI ELISA Kit for Human(Homo sapiens) | EIAab.comTGFBI ELISA Kit for Human(Homo sapiens)

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Index > Protein center > TGFBI(Gene name) > Human

TGFBI (Gene name),

Transforming growth factor-beta-induced protein ig-h3 (Protein name ), BGH3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

TGFBI(BIGH3);

Protein name:

Transforming growth factor-beta-induced protein ig-h3(Beta ig-h3);

Alternative:

RGD-containing collagen-associated protein(RGD-CAP);Kerato-epithelin;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Binds to type I, II, and IV collagens. This adhesion protein may play an important role in cell-collagen interactions. In cartilage, may be involved in endochondral bone formation.

Subcellular Location:

Secreted extracellular space extracellular matrix May be associated both with microfibrils and with the cell surface.

Protein Attributes:

Sequence length:

683

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

683:

LEIFKQASAF | SRASQRSVRL | APVYQKLLER | MKH

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:7045

UniGene:

Hs.369397

Pfam:

PF02469

SMR:

Q15582

STRING:

9606.ENSP00000416330

MIM:

121820

String:

Q15582

Uniprot:

Q15582

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ELISA Kit for Human Beta ig-h3

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E9124h

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96T

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ELISA Kit for Human Beta ig-h3

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ELISA Kit for Human Beta ig-h3

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E9124m

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96T

ELISA Kit for Human Beta ig-h3

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ELISA Kit for Human Beta ig-h3

Cat.:

E9124p

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Packing:

96T

CLIA Kit for Human Beta ig-h3

Cat.:

U9124m

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96T

CLIA Kit for Human Beta ig-h3

Cat.:

U9124p

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96T

CLIA Kit for Human Beta ig-h3

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CLIA Kit for Human Beta ig-h3

Cat.:

U9124h

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96T

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CLIA Kit for Human Beta ig-h3

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Polyclonal Antibody for Human Beta ig-h3

Cat.:

P9124Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Beta ig-h3

Cat.:

P9124Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Beta ig-h3

Monoclonal Antibody for Human Beta ig-h3

Protein for Human Beta ig-h3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"cDNA cloning and sequence analysis of beta ig-h3, a novel gene induced in a human adenocarcinoma cell line after treatment with transforming growth factor-beta."
Skonier J. , Neubauer M. , Madisen L. , Bennett K. , Plowman G.D. , Purchio A.F.
DNA Cell Biol.11:511-522(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Kerato-epithelin mutations in four 5q31-linked corneal dystrophies."
Munier F.L. , Korvatska E. , Djemai A. , le Paslier D. , Zografos L. , Pescia G. , Schorderet D.F.
Nat. Genet.15:247-251(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS CORNEAL DYSTROPHIES CYS-124; HIS-124; GLN-555 AND TRP-555
3.

NIEHS SNPs program
Submitted (2002-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT PHE-200
4.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
5.

"The DNA sequence and comparative analysis of human chromosome 5."
Schmutz J. , Martin J. , Terry A. , Couronne O. , Grimwood J. , Lowry S. , Gordon L.A. , Scott D. , Xie G. , Huang W. , Hellsten U. , Tran-Gyamfi M. , She X. , Prabhakar S. , Aerts A. , Altherr M. , Bajorek E. , Black S. , more...
Nature431:268-274(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Kidney.
8.

"cDNA from human ocular ciliary epithelium homologous to beta ig-h3 is preferentially expressed as an extracellular protein in the corneal epithelium."
Escribano J. , Hernando N. , Ghosh S. , Crabb J. , Coca-Prados M.
J. Cell. Physiol.160:511-521(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
9.

"Corneal dystrophies in Japan."
Fujiki K. , Nakayasu K. , Kanai A.
J. Hum. Genet.46:431-435(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS CORNEAL DYSTROPHIES
10.

"Solution structure of the FAS1 domain of human transforming growth factor-beta induced protein IG-H3."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-01) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 502-634
11.

"Mutation hot spots in 5q31-linked corneal dystrophies."
Korvatska E. , Munier F.L. , Djemai A. , Wang M.X. , Frueh B. , Chiou A.G.-Y. , Uffer S. , Ballestrazzi E. , Braunstein R.E. , Forster R.K. , Culbertson W.W. , Boman H. , Zografos L. , Schorderet D.F.
Am. J. Hum. Genet.62:320-324(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES CYS-124; HIS-124; GLN-555 AND TRP-555
12.

"A kerato-epithelin (beta-ig-h3) mutation in lattice corneal dystrophy type IIIA."
Yamamoto S. , Okada M. , Tsujikawa M. , Shimomura Y. , Nishida K. , Inoue Y. , Watanabe H. , Maeda N. , Kurahashi H. , Kinoshita S. , Nakamura Y. , Tano Y.
Am. J. Hum. Genet.62:719-722(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL3A THR-501
13.

"Two distinct kerato-epithelin mutations in Reis-Bucklers corneal dystrophy."
Okada M. , Yamamoto S. , Tsujikawa M. , Watanabe H. , Inoue Y. , Maeda N. , Shimomura Y. , Nishida K. , Quantock A.J. , Kinoshita S. , Tano Y.
Am. J. Ophthalmol.126:535-542(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDRB LEU-124
14.

"A new L527R mutation of the betaIGH3 gene in patients with lattice corneal dystrophy with deep stromal opacities."
Fujiki K. , Hotta Y. , Nakayasu K. , Yokoyama T. , Takano T. , Yamaguchi T. , Kanai A.
Hum. Genet.103:286-289(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 ARG-527
15.

"A common beta ig-h3 gene mutation (delta F540) in a large cohort of Sardinian Reis Buecklers' corneal dystrophy patients."
Rozzo C. , Fossarello M. , Galleri G. , Sole G. , Serru A. , Orzalesi N. , Serra A. , Pirastu M.
Hum. Mutat.12:215-216(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDRB PHE-540 DEL
16.

"Heterogeneity in granular corneal dystrophy: identification of three causative mutations in the TGFBI (BIGH3) gene-lessons for corneal amyloidogenesis."
Stewart H.S. , Ridgway A.E. , Dixon M.J. , Bonshek R.E. , Parveen R. , Black G.C.
Hum. Mutat.14:126-132(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES HIS-124; SER-124 AND TRP-555
17.

"A mutation within exon 14 of the TGFBI (BIGH3) gene on chromosome 5q31 causes an asymmetric, late-onset form of lattice corneal dystrophy."
Stewart H.S. , Black G.C. , Donnai D. , Bonshek R.E. , McCarthy J. , Morgan S. , Dixon M.J. , Ridgway A.A.
Ophthalmology106:964-970(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CDL HIS-622 AND ARG-626
18.

"Association of autosomal dominantly inherited corneal dystrophies with BIGH3 gene mutations in Japan."
Mashima Y. , Yamamoto S. , Inoue Y. , Yamada M. , Konishi M. , Watanabe H. , Maeda N. , Shimomura Y. , Kinoshita S.
Am. J. Ophthalmol.130:516-517(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES CYS-124; HIS-124; LEU-124; THR-501; ARG-527; SER-544; GLN-555 AND TRP-555
19.

"A novel variant of granular corneal dystrophy caused by association of 2 mutations in the TGFBI gene-R124L and deltaT125-deltaE126."
Dighiero P. , Drunat S. , D'Hermies F. , Renard G. , Delpech M. , Valleix S.
Arch. Ophthalmol.118:814-818(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES LEU-124 AND 125-THR-GLU-126 DEL
20.

"Corneal amyloidosis caused by Leu518Pro mutation of betaig-h3 gene."
Hirano K. , Hotta Y. , Fujiki K. , Kanai A.
Br. J. Ophthalmol.84:583-585(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 PRO-518
21.

"Late-onset form of lattice corneal dystrophy caused by Leu527Arg mutation of the TGFBI gene."
Hirano K. , Hotta Y. , Nakamura M. , Fujiki K. , Kanai A. , Yamamoto N.
Cornea20:525-529(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 ARG-527
22.

"Histologic phenotype-genotype correlation of corneal dystrophies associated with eight distinct mutations in the TGFBI gene."
Dighiero P. , Niel F. , Ellies P. , D'Hermies F. , Savoldelli M. , Renard G. , Delpech M. , Valleix S.
Ophthalmology108:818-823(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES CYS-124; HIS-124; LEU-124; 125-THR-GLU-126 DEL; THR-546; GLN-555; TRP-555 AND ARG-626
23.

"BIGH3 mutation spectrum in corneal dystrophies."
Munier F.L. , Frueh B.E. , Othenin-Girard P. , Uffer S. , Cousin P. , Wang M.X. , Heon E. , Black G.C.M. , Blasi M.A. , Balestrazzi E. , Lorenz B. , Escoto R. , Barraquer R. , Hoeltzenbein M. , Gloor B. , Fossarello M. , Singh A.D. , Arsenijevic Y. , more...
Invest. Ophthalmol. Vis. Sci.43:949-954(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CORNEAL DYSTROPHIES CYS-124; HIS-124; SER-124; ARG-518; ARG-538; PHE-540 DEL; TRP-555; LYS-622; ASP-623; ARG-626; PRO-626 AND ASP-631
24.

"A new mutation (Leu569Arg) within exon 13 of the TGFBI (BIGH3) gene causes lattice corneal dystrophy type I."
Warren J.F. , Abbott R.L. , Yoon M.K. , Crawford J.B. , Spencer W.H. , Margolis T.P.
Am. J. Ophthalmol.136:872-878(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 ARG-569
25.

"A novel mutation of the TGFBI gene found in a Vietnamese family with atypical granular corneal dystrophy."
Ha N.T. , Cung le X. , Chau H.M. , Thanh T.K. , Fujiki K. , Murakami A. , Kanai A.
Jpn. J. Ophthalmol.47:246-248(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GRANULAR CORNEAL DYSTROPHY HIS-123
26.

"Lattice corneal dystrophy associated with the Ala546Asp and Pro551Gln missense changes in the TGFBI gene."
Aldave A.J. , Gutmark J.G. , Yellore V.S. , Affeldt J.A. , Meallet M.A. , Udar N. , Rao N.A. , Small K.W. , Klintworth G.K.
Am. J. Ophthalmol.138:772-781(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CDL1 ASP-546 AND GLN-551
27.

"TGFBI gene mutations causing lattice and granular corneal dystrophies in Indian patients."
Chakravarthi S.V.V.K. , Kannabiran C. , Sridhar M.S. , Vemuganti G.K.
Invest. Ophthalmol. Vis. Sci.46:121-125(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CDL1 CYS-124 AND ARG-626;VARIANT CDRB LEU-124;VARIANT CDGG1 TRP-555;VARIANTS LATTICE CORNEAL DYSTROPHY ASP-539; VAL-594 AND 624-VAL-VAL-625 DEL;VARIANT PHE-269
28.

"Hereditary lattice corneal dystrophy is associated with corneal amyloid deposits enclosing C-terminal fragments of keratoepithelin."
Stix B. , Leber M. , Bingemer P. , Gross C. , Rueschoff J. , Faendrich M. , Schorderet D.F. , Vorwerk C.K. , Zacharias M. , Roessner A. , Roecken C.
Invest. Ophthalmol. Vis. Sci.46:1133-1139(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL3A SER-540
29.

"Novel mutation (V505D) of the TGFBI gene found in a Chinese family with lattice corneal dystrophy, type I."
Tian X. , Fujiki K. , Wang W. , Murakami A. , Xie P. , Kanai A. , Liu Z.
Jpn. J. Ophthalmol.49:84-88(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 ASP-505
30.

"A subset of patients with epithelial basement membrane corneal dystrophy have mutations in TGFBI/BIGH3."
Boutboul S. , Black G.C.M. , Moore J.E. , Sinton J. , Menasche M. , Munier F.L. , Laroche L. , Abitbol M. , Schorderet D.F.
Hum. Mutat.27:553-557(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS EBMD ARG-509 AND SER-666
31.

"A novel H572R mutation in the transforming growth factor-beta-induced gene in a Thai family with lattice corneal dystrophy type I."
Atchaneeyasakul L.-O. , Appukuttan B. , Pingsuthiwong S. , Yenchitsomanus P.-T. , Trinavarat A. , Srisawat C.
Jpn. J. Ophthalmol.50:403-408(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 ARG-572
32.

"Unilateral lattice corneal dystrophy associated with the novel His572del mutation in the TGFBI gene."
Aldave A.J. , Rayner S.A. , Kim B.T. , Prechanond A. , Yellore V.S.
Mol. Vis.12:142-146(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CDL1 HIS-572 DEL
33.

"Expanding the mutational spectrum in TGFBI-linked corneal dystrophies: identification of a novel and unusual mutation (Val113Ile) in a family with granular dystrophy."
Zenteno J.C. , Ramirez-Miranda A. , Santacruz-Valdes C. , Suarez-Sanchez R.
Mol. Vis.12:331-335(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GRANULAR CORNEAL DYSTROPHY ILE-113

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