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Index > Protein center > BMP15(Gene name) > Human
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  • BMP15 (Gene name),
  • Bone morphogenetic protein 15 (Protein name ),  BMP15_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    BMP15(GDF9B);
    Protein name:
    Bone morphogenetic protein 15(BMP-15);
    Alternative:
    Growth/differentiation factor 9B(GDF-9B);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homodimer. But, in contrast to other members of this family, cannot be disulfide-linked.
    Function:
    May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    392
    Sequence:
    50:
    MVLLSILRIL | FLCELVLFME | HRAQMAEGGQ | SSIALLAEAP | TLPLIEELLE | 
    100:
    ESPGEQPRKP | RLLGHSLRYM | LELYRRSADS | HGHPRENRTI | GATMVRLVKP | 
    150:
    LTNVARPHRG | TWHIQILGFP | LRPNRGLYQL | VRATVVYRHH | LQLTRFNLSC | 
    200:
    HVEPWVQKNP | TNHFPSSEGD | SSKPSLMSNA | WKEMDITQLV | QQRFWNNKGH | 
    250:
    RILRLRFMCQ | QQKDSGGLEL | WHGTSSLDIA | FLLLYFNDTH | KSIRKAKFLP | 
    300:
    RGMEEFMERE | SLLRRTRQAD | GISAEVTASS | SKHSGPENNQ | CSLHPFQISF | 
    350:
    RQLGWDHWII | APPFYTPNYC | KGTCLRVLRD | GLNSPNHAII | QNLINQLVDQ | 
    392:
    SVPRPSCVPY | KYVPISVLMI | EANGSILYKE | YEGMIAESCT | CR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    KEGG:
    MIM:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human BMP-15
    Cat.:
    E1469h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
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    Please sign in first.
    ELISA Kit for Human BMP-15
    Cat.:
    E1469b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human BMP-15
    Cat.:
    E1469m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human BMP-15
    Cat.:
    U1469h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human BMP-15
    Cat.:
    U1469m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human BMP-15
    Cat.:
    U1469b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human BMP-15
    Polyclonal Antibody for Human BMP-15
    Cat.:
    P1469Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human BMP-15
    Cat.:
    P1469Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human BMP-15
    Monoclonal Antibody for Human BMP-15
    Monoclonal Antibody for Human BMP-15
    Protein for Human BMP-15
    Protein for Human BMP-15
    Protein for Human BMP-15

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The bone morphogenetic protein 15 gene is X-linked and expressed in oocytes."
      Dube J.L. , Wang P. , Elvin J. , Lyons K.M. , Celeste A.J. , Matzuk M.M.
      Mol. Endocrinol.12:1809-1817(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT SER-103
    2. 2.
      "Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis."
      Aaltonen J. , Laitinen M.P. , Vuojolainen K. , Jaatinen R. , Horelli-Kuitunen N. , Seppae L. , Louhio H. , Tuuri T. , Sjoeberg J. , Buetzow R. , Hovatta O. , Dale L. , Ritvos O.
      J. Clin. Endocrinol. Metab.84:2744-2750(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "The DNA sequence of the human X chromosome."
      Ross M.T. , Grafham D.V. , Coffey A.J. , Scherer S. , McLay K. , Muzny D. , Platzer M. , Howell G.R. , Burrows C. , Bird C.P. , Frankish A. , Lovell F.L. , Howe K.L. , Ashurst J.L. , Fulton R.S. , Sudbrak R. , Wen G. , Jones M.C. , more...
      Nature434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    5. 5.
      "Characterization of the post-translational modification of recombinant human BMP-15 mature protein."
      Saito S. , Yano K. , Sharma S. , McMahon H.E. , Shimasaki S.
      Protein Sci.17:362-370(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PYROGLUTAMATE FORMATION AT GLN-268;PHOSPHORYLATION AT SER-273;GLYCOSYLATION AT THR-277;HOMODIMERIZATION
    6. 6.
      "The ratio of growth differentiation factor 9: bone morphogenetic protein 15 mRNA expression is tightly co-regulated and differs between species over a wide range of ovulation rates."
      Crawford J.L. , McNatty K.P.
      Mol. Cell. Endocrinol.348:339-343(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SPECIES-SPECIFIC OVULATION RATE DETERMINATION
    7. 7.
      "Hypergonadotropic ovarian failure associated with an inherited mutation of human bone morphogenetic protein-15 (BMP15) gene."
      Di Pasquale E. , Beck-Peccoz P. , Persani L.
      Am. J. Hum. Genet.75:106-111(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ODG2 CYS-235;CHARACTERIZATION OF VARIANT ODG2 CYS-235
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS POF4 PRO-148 AND THR-180;VARIANT LEU-263 INS
    9. 9.
      "Missense mutations in the BMP15 gene are associated with ovarian failure."
      Dixit H. , Rao L.K. , Padmalatha V.V. , Kanakavalli M. , Deenadayal M. , Gupta N. , Chakrabarty B. , Singh L.
      Hum. Genet.119:408-415(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS POF4 TRP-61; GLN-61; CYS-76; HIS-76; THR-180; LYS-196; HIS-206; ARG-221 AND VAL-243;VARIANTS SER-103; PHE-180 AND LEU-263 INS
    10. 10.
      "Identification of new variants of human BMP15 gene in a large cohort of women with premature ovarian failure."
      Di Pasquale E. , Rossetti R. , Marozzi A. , Bodega B. , Borgato S. , Cavallo L. , Einaudi S. , Radetti G. , Russo G. , Sacco M. , Wasniewska M. , Cole T. , Beck-Peccoz P. , Nelson L.M. , Persani L.
      J. Clin. Endocrinol. Metab.91:1976-1979(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS POF4 TRP-68; THR-180 AND CYS-235;VARIANT LEU-263 INS
    11. 11.
      "BMP15 mutations associated with primary ovarian insufficiency cause a defective production of bioactive protein."
      Rossetti R. , Di Pasquale E. , Marozzi A. , Bione S. , Toniolo D. , Grammatico P. , Nelson L.M. , Beck-Peccoz P. , Persani L.
      Hum. Mutat.30:804-810(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS POF4 TRP-68; HIS-138; PRO-148 AND THR-180;VARIANTS ARG-5 AND LEU-263 INS;CHARACTERIZATION OF VARIANTS POF4 TRP-68; HIS-138; PRO-148 AND THR-180;CHARACTERIZATION OF VARIANTS ARG-5 AND LEU-263 INS
    12. 12.
      "Analyses of growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) mutation in Chinese women with premature ovarian failure."
      Wang B. , Wen Q. , Ni F. , Zhou S. , Wang J. , Cao Y. , Ma X.
      Clin. Endocrinol. (Oxf.)72:135-136(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT TYR-200;VARIANT POF4 CYS-329
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