Bmp2 ELISA Kit for Mouse(Mus musculus) | EIAab.comBmp2 ELISA Kit for Mouse(Mus musculus)

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Bmp2 (Gene name),

Bone morphogenetic protein 2 (Protein name ), BMP2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Bmp2(Bmp-2);

Protein name:

Bone morphogenetic protein 2(BMP-2);

Alternative:

Bone morphogenetic protein 2A(BMP-2A);

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer; disulfide-linked. Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC. Interacts with ASPN.

Function:

Induces cartilage and bone formation.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

394

Sequence:

50:

100:

150:

200:

250:

300:

350:

394:

NSKIPKACCV | PTELSAISML | YLDENEKVVL | KNYQDMVVEG | CGCR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF00019

String:

P21274

UniGene:

Mm.103205

SMR:

P21274

KEGG:

mmu:12156

Uniprot:

P21274

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ELISA Kit for Mouse BMP-2

Cat.:

E0013h

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96T

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ELISA Kit for Mouse BMP-2

Cat.:

E0013m

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96T

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ELISA Kit for Mouse BMP-2

Cat.:

E0013r

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96T

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ELISA Kit for Mouse BMP-2

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ELISA Kit for Mouse BMP-2

Cat.:

E0013c

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96T

CLIA Kit for Mouse BMP-2

MSDS:

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CLIA Kit for Mouse BMP-2

Cat.:

U0013r

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96T

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CLIA Kit for Mouse BMP-2

Cat.:

U0013m

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Looking for manual.

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96T

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CLIA Kit for Mouse BMP-2

Cat.:

U0013h

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Looking for manual.

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96T

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CLIA Kit for Mouse BMP-2

Cat.:

U0013c

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96T

Polyclonal Antibody for Mouse BMP-2

Cat.:

P0013Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse BMP-2

Cat.:

P0013Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse BMP-2

Cat.:

P0013Rb-r

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40ug/0.2ml

Polyclonal Antibody for Mouse BMP-2

Monoclonal Antibody for Mouse BMP-2

Protein for Mouse BMP-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

Intra-Assay CV: ≤4.2%

Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

Inter-Assay CV: ≤7.6%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

Recovery was determined by spiking various levels of BMP2 into serum and plasma .

Sample Type	Average(%)	Recovery Range(%)
Serum	101	98-103
Plasma	100	99-106

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

The linearity of the kit was assayed by testing samples spiked with appropriate concentration of BMP2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.

Sample	1：2	1:4	1:8	1:16
serum(n=5)	101-105%	96-101%	99-105%	103-106%
EDTA plasma(n=5)	99-105%	102-104%	95-99%	98-104%
heparin plasma(n=5)	100-106%	92-97%	101-104%	106-110%

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes."
Feng J.Q. , Harris M.A. , Ghosh-Choudhury N. , Feng M. , Mundy G.R. , Harris S.E.
Biochim. Biophys. Acta1218:221-224(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Embryo.
tissue: Medulla oblongata.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thyroid.
6.

"Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci."
Dickinson M.E. , Kobrin M.S. , Silan C.M. , Kingsley D.M. , Justice M.J. , Miller D.A. , Ceci J.D. , Lock L.F. , Lee A. , Buchberg A.M. , Siracusa L.D. , Lyons K.M. , Derynck R. , Hogan B.L.M. , Copeland N.G. , Jenkins N.A.
Genomics6:505-520(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-351
7.

"Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot."
Laurikkala J. , Kassai Y. , Pakkasjaervi L. , Thesleff I. , Itoh N.
Dev. Biol.264:91-105(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SOSTDC1
8.

"Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation."
Sudo S. , Avsian-Kretchmer O. , Wang L.S. , Hsueh A.J.
J. Biol. Chem.279:23134-23141(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GREM2
9.

"DRAGON, a bone morphogenetic protein co-receptor."
Samad T.A. , Rebbapragada A. , Bell E. , Zhang Y. , Sidis Y. , Jeong S.-J. , Campagna J.A. , Perusini S. , Fabrizio D.A. , Schneyer A.L. , Lin H.Y. , Brivanlou A.H. , Attisano L. , Woolf C.J.
J. Biol. Chem.280:14122-14129(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMB
10.

"Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor."
Babitt J.L. , Zhang Y. , Samad T.A. , Xia Y. , Tang J. , Campagna J.A. , Schneyer A.L. , Woolf C.J. , Lin H.Y.
J. Biol. Chem.280:29820-29827(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA
11.

"Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression."
Babitt J.L. , Huang F.W. , Wrighting D.M. , Xia Y. , Sidis Y. , Samad T.A. , Campagna J.A. , Chung R.T. , Schneyer A.L. , Woolf C.J. , Andrews N.C. , Lin H.Y.
Nat. Genet.38:531-539(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMC
12.

"Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4."
Xia Y. , Yu P.B. , Sidis Y. , Beppu H. , Bloch K.D. , Schneyer A.L. , Lin H.Y.
J. Biol. Chem.282:18129-18140(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA
13.

"PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization."
Yamada S. , Tomoeda M. , Ozawa Y. , Yoneda S. , Terashima Y. , Ikezawa K. , Ikegawa S. , Saito M. , Toyosawa S. , Murakami S.
J. Biol. Chem.282:23070-23080(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASPN

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