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Index > Protein center > Bmp2(Gene name) > Mouse
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  • Bmp2 (Gene name),
  • Bone morphogenetic protein 2 (Protein name ),  BMP2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Bmp2(Bmp-2);
    Protein name:
    Bone morphogenetic protein 2(BMP-2);
    Alternative:
    Bone morphogenetic protein 2A(BMP-2A);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homodimer; disulfide-linked. Interacts with SOSTDC1, GREM2, RGMA, RGMB and RGMC. Interacts with ASPN.
    Function:
    Induces cartilage and bone formation.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    394
    Sequence:
    50:
    MVAGTRCLLV | LLLPQVLLGG | AAGLIPELGR | KKFAAASSRP | LSRPSEDVLS | 
    100:
    EFELRLLSMF | GLKQRPTPSK | DVVVPPYMLD | LYRRHSGQPG | APAPDHRLER | 
    150:
    AASRANTVRS | FHHEEAVEEL | PEMSGKTARR | FFFNLSSVPS | DEFLTSAELQ | 
    200:
    IFREQIQEAL | GNSSFQHRIN | IYEIIKPAAA | NLKFPVTRLL | DTRLVNQNTS | 
    250:
    QWESFDVTPA | VMRWTTQGHT | NHGFVVEVAH | LEENPGVSKR | HVRISRSLHQ | 
    300:
    DEHSWSQIRP | LLVTFGHDGK | GHPLHKREKR | QAKHKQRKRL | KSSCKRHPLY | 
    350:
    VDFSDVGWND | WIVAPPGYHA | FYCHGECPFP | LADHLNSTNH | AIVQTLVNSV | 
    394:
    NSKIPKACCV | PTELSAISML | YLDENEKVVL | KNYQDMVVEG | CGCR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse BMP-2
    Cat.:
    E0013h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BMP-2
    Cat.:
    E0013m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BMP-2
    Cat.:
    E0013r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse BMP-2
    MSDS:
    Please sign in first.
    ELISA Kit for Mouse BMP-2
    Cat.:
    E0013c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse BMP-2
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse BMP-2
    Cat.:
    U0013r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse BMP-2
    Cat.:
    U0013m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse BMP-2
    Cat.:
    U0013h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse BMP-2
    Cat.:
    U0013c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse BMP-2
    Cat.:
    P0013Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse BMP-2
    Cat.:
    P0013Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse BMP-2
    Polyclonal Antibody for Mouse BMP-2
    Polyclonal Antibody for Mouse BMP-2
    Cat.:
    P0013Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse BMP-2
    Monoclonal Antibody for Mouse BMP-2
    Monoclonal Antibody for Mouse BMP-2
    Monoclonal Antibody for Mouse BMP-2
    Monoclonal Antibody for Mouse BMP-2
    Protein for Mouse BMP-2
    Protein for Mouse BMP-2
    Protein for Mouse BMP-2
    Protein for Mouse BMP-2
    Protein for Mouse BMP-2

    R&D Technical Data

    s

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.2%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.6%

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    Recovery

    Recovery was determined by spiking various levels of BMP2 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    101

    98-103

    Plasma

    100

    99-106

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of BMP2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    101-105%

    96-101%

    99-105%

    103-106%

    EDTA plasma(n=5)

    99-105%

    102-104%

    95-99%

    98-104%

    heparin plasma(n=5)

    100-106%

     

    92-97%

    101-104%

    106-110%

     

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes."
      Feng J.Q. , Harris M.A. , Ghosh-Choudhury N. , Feng M. , Mundy G.R. , Harris S.E.
      Biochim. Biophys. Acta1218:221-224(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Embryo.
      tissue: Medulla oblongata.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Thyroid.
    6. 6.
      "Chromosomal localization of seven members of the murine TGF-beta superfamily suggests close linkage to several morphogenetic mutant loci."
      Dickinson M.E. , Kobrin M.S. , Silan C.M. , Kingsley D.M. , Justice M.J. , Miller D.A. , Ceci J.D. , Lock L.F. , Lee A. , Buchberg A.M. , Siracusa L.D. , Lyons K.M. , Derynck R. , Hogan B.L.M. , Copeland N.G. , Jenkins N.A.
      Genomics6:505-520(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-351
    7. 7.
      "Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot."
      Laurikkala J. , Kassai Y. , Pakkasjaervi L. , Thesleff I. , Itoh N.
      Dev. Biol.264:91-105(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SOSTDC1
    8. 8.
      "Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation."
      Sudo S. , Avsian-Kretchmer O. , Wang L.S. , Hsueh A.J.
      J. Biol. Chem.279:23134-23141(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GREM2
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMB
    10. 10.
      "Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor."
      Babitt J.L. , Zhang Y. , Samad T.A. , Xia Y. , Tang J. , Campagna J.A. , Schneyer A.L. , Woolf C.J. , Lin H.Y.
      J. Biol. Chem.280:29820-29827(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA
    11. 11.
      "Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression."
      Babitt J.L. , Huang F.W. , Wrighting D.M. , Xia Y. , Sidis Y. , Samad T.A. , Campagna J.A. , Chung R.T. , Schneyer A.L. , Woolf C.J. , Andrews N.C. , Lin H.Y.
      Nat. Genet.38:531-539(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMC
    12. 12.
      "Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4."
      Xia Y. , Yu P.B. , Sidis Y. , Beppu H. , Bloch K.D. , Schneyer A.L. , Lin H.Y.
      J. Biol. Chem.282:18129-18140(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RGMA
    13. 13.
      "PLAP-1/asporin, a novel negative regulator of periodontal ligament mineralization."
      Yamada S. , Tomoeda M. , Ozawa Y. , Yoneda S. , Terashima Y. , Ikezawa K. , Ikegawa S. , Saito M. , Toyosawa S. , Murakami S.
      J. Biol. Chem.282:23070-23080(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ASPN
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