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Index > Protein center > CD93(Gene name) > Human
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  • CD93 (Gene name),
  • Complement component C1q receptor (Protein name ),  C1QR1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CD93(C1QR1;MXRA4);
    Protein name:
    Complement component C1q receptor;
    Alternative:
    CDw93;C1q/MBL/SPA receptor(C1qR;C1qR(p);C1qRp);Matrix-remodeling-associated protein 4;Complement component 1 q subcomponent receptor 1;
    CD:
    CD93;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HCV core protein.
    Function:
    Receptor (or element of a larger receptor complex) for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). May mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens. May play a role in intercellular adhesion.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    652
    Sequence:
    50:
    MATSMGLLLL | LLLLLTQPGA | GTGADTEAVV | CVGTACYTAH | SGKLSAAEAQ | 
    100:
    NHCNQNGGNL | ATVKSKEEAQ | HVQRVLAQLL | RREAALTARM | SKFWIGLQRE | 
    150:
    KGKCLDPSLP | LKGFSWVGGG | EDTPYSNWHK | ELRNSCISKR | CVSLLLDLSQ | 
    200:
    PLLPSRLPKW | SEGPCGSPGS | PGSNIEGFVC | KFSFKGMCRP | LALGGPGQVT | 
    250:
    YTTPFQTTSS | SLEAVPFASA | ANVACGEGDK | DETQSHYFLC | KEKAPDVFDW | 
    300:
    GSSGPLCVSP | KYGCNFNNGG | CHQDCFEGGD | GSFLCGCRPG | FRLLDDLVTC | 
    350:
    ASRNPCSSSP | CRGGATCVLG | PHGKNYTCRC | PQGYQLDSSQ | LDCVDVDECQ | 
    400:
    DSPCAQECVN | TPGGFRCECW | VGYEPGGPGE | GACQDVDECA | LGRSPCAQGC | 
    450:
    TNTDGSFHCS | CEEGYVLAGE | DGTQCQDVDE | CVGPGGPLCD | SLCFNTQGSF | 
    500:
    HCGCLPGWVL | APNGVSCTMG | PVSLGPPSGP | PDEEDKGEKE | GSTVPRAATA | 
    550:
    SPTRGPEGTP | KATPTTSRPS | LSSDAPITSA | PLKMLAPSGS | PGVWREPSIH | 
    600:
    HATAASGPQE | PAGGDSSVAT | QNNDGTDGQK | LLLFYILGTV | VAILLLLALA | 
    650:
    LGLLVYRKRR | AKREEKKEKK | PQNAADSYSW | VPERAESRAM | ENQYSPTPGT | 
    652:
    DC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    Pfam:
    UniGene:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Complement component C1q receptor
    Cat.:
    E2086m
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    Packing:
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    ELISA Kit for Human Complement component C1q receptor
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    E2086h
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    ELISA Kit for Human Complement component C1q receptor
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    E2086r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Complement component C1q receptor
    Cat.:
    U2086r
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Complement component C1q receptor
    Cat.:
    U2086h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Complement component C1q receptor
    Cat.:
    U2086m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human Complement component C1q receptor
    Cat.:
    P2086Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Complement component C1q receptor
    Cat.:
    P2086Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Complement component C1q receptor
    Cat.:
    P2086Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Complement component C1q receptor
    Monoclonal Antibody for Human Complement component C1q receptor
    Monoclonal Antibody for Human Complement component C1q receptor
    Protein for Human Complement component C1q receptor
    Protein for Human Complement component C1q receptor
    Protein for Human Complement component C1q receptor

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    Linearity
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    References
    1. 1.
      "cDNA cloning and primary structure analysis of C1qR(P), the human C1q/MBL/SPA receptor that mediates enhanced phagocytosis in vitro."
      Nepomuceno R.R. , Henschen-Edman A.H. , Burgess W.H. , Tenner A.J.
      Immunity6:119-129(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE;VARIANT SER-541
    2. 2.
      "Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloning."
      Steinberger P. , Szekeres A. , Wille S. , Stockl J. , Selenko N. , Prager E. , Staffler G. , Madic O. , Stockinger H. , Knapp W.
      J. Leukoc. Biol.71:133-140(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ALA-318
    3. 3.
      "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P. , Matthews L.H. , Ashurst J.L. , Burton J. , Gilbert J.G.R. , Jones M. , Stavrides G. , Almeida J.P. , Babbage A.K. , Bagguley C.L. , Bailey J. , Barlow K.F. , Bates K.N. , Beard L.M. , Beare D.M. , Beasley O.P. , Bird C.P. , Blakey S.E. , more...
      Nature414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Leukocyte.
    5. 5.
      "Evidence that the two C1q binding membrane proteins, gC1q-R and cC1q-R, associate to form a complex."
      Ghebrehiwet B. , Lu P.D. , Zhang W. , Keilbaugh S.A. , Leigh L.E. , Eggleton P. , Reid K.B. , Peerschke E.I.
      J. Immunol.159:1429-1436(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH C1QBP
    6. 6.
      "Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1q."
      McGreal E.P. , Ikewaki N. , Akatsu H. , Morgan B.P. , Gasque P.
      J. Immunol.168:5222-5232(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    7. 7.
      "C1qRP is a heavily O-glycosylated cell surface protein involved in the regulation of phagocytic activity."
      Nepomuceno R.R. , Ruiz S. , Park M. , Tenner A.J.
      J. Immunol.162:3583-3589(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION
    8. 8.
      "Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation."
      Kittlesen D.J. , Chianese-Bullock K.A. , Yao Z.Q. , Braciale T.J. , Hahn Y.S.
      J. Clin. Invest.106:1239-1249(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH HCV CORE PROTEIN
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-220
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