CA1 ELISA Kit for Human(Homo sapiens) | EIAab.comCA1 ELISA Kit for Human(Homo sapiens)

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CA1 (Gene name),

Carbonic anhydrase 1 (Protein name ), CAH1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CA1;

Protein name:

Carbonic anhydrase 1;

Alternative:

Carbonic anhydrase B(CAB);Carbonate dehydratase I;Carbonic anhydrase I(CA-I);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Reversible hydration of carbon dioxide. Can hydrates cyanamide to urea.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

261

Sequence:

50:

100:

150:

200:

250:

261:

PLKGRTVRAS | F

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.23118

String:

P00915

SMR:

P00915

STRING:

9606.ENSP00000256119

KEGG:

hsa:759

Pfam:

PF00194

MIM:

114800

Uniprot:

P00915

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ELISA Kit for Human Carbonic anhydrase 1

Cat.:

E1799h

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96T

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ELISA Kit for Human Carbonic anhydrase 1

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ELISA Kit for Human Carbonic anhydrase 1

Cat.:

E1799r

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96T

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ELISA Kit for Human Carbonic anhydrase 1

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E1799b

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96T

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ELISA Kit for Human Carbonic anhydrase 1

Cat.:

E1799m

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96T

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CLIA Kit for Human Carbonic anhydrase 1

Cat.:

U1799r

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96T

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CLIA Kit for Human Carbonic anhydrase 1

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CLIA Kit for Human Carbonic anhydrase 1

Cat.:

U1799b

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Packing:

96T

CLIA Kit for Human Carbonic anhydrase 1

Cat.:

U1799m

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96T

CLIA Kit for Human Carbonic anhydrase 1

Cat.:

U1799h

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96T

Polyclonal Antibody for Human Carbonic anhydrase 1

Cat.:

P1799Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Carbonic anhydrase 1

Cat.:

P1799Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Carbonic anhydrase 1

Cat.:

P1799Rb-r

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40ug/0.2ml

Monoclonal Antibody for Human Carbonic anhydrase 1

Protein for Human Carbonic anhydrase 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"Human carbonic anhydrase I cDNA."
Barlow J.H. , Lowe N. , Edwards Y.H. , Butterworth P.H.W.
Nucleic Acids Res.15:2386-2386(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Structure and methylation patterns of the gene encoding human carbonic anhydrase I."
Lowe N. , Brady H.J.M. , Barlow J.H. , Sowden J.C. , Edwards M. , Butterworth P.H.W.
Gene93:277-283(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
tissue: Spleen.
4.

"Primary structure of human B erythrocyte carbonic anhydrase. 3. Sequence of CNBr fragment I and III (residues 149-260)."
Giraud N. , Marriq C. , Laurent-Tabusse G.
Biochimie56:1031-1043(1974) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-261;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT ALA-2
5.

"Amino acid sequence of human erythrocyte carbonic anhydrase B."
Andersson B. , Nyman P.O. , Strid L.
Biochem. Biophys. Res. Commun.48:670-677(1972) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 20-261
6.

"Human carbonic anhydrases. XI. The complete primary structure of carbonic anhydrase B."
Lin K.-T.D. , Deutsch H.F.
J. Biol. Chem.248:1885-1893(1973) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 12-261
7.

"Human carbonic anhydrases. XII. The complete primary structure of the C isozyme."
Lin K.-T.D. , Deutsch H.F.
J. Biol. Chem.249:2329-2337(1974) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
8.

"Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction?"
Briganti F. , Mangani S. , Scozzafava A. , Vernaglione G. , Supuran C.T.
J. Biol. Inorg. Chem.4:528-536(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
9.

"Carbonic anhydrase activators. Activation of isozymes I, II, IV, VA, VII, and XIV with l- and d-histidine and crystallographic analysis of their adducts with isoform II: engineering proton-transfer processes within the active site of an enzyme."
Temperini C. , Scozzafava A. , Vullo D. , Supuran C.T.
Chemistry12:7057-7066(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
10.

"Carbonic anhydrase activators. Activation of isoforms I, II, IV, VA, VII, and XIV with L- and D-phenylalanine and crystallographic analysis of their adducts with isozyme II: stereospecific recognition within the active site of an enzyme and its consequences for the drug design."
Temperini C. , Scozzafava A. , Vullo D. , Supuran C.T.
J. Med. Chem.49:3019-3027(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
11.

"Carbonic anhydrase activators: L-Adrenaline plugs the active site entrance of isozyme II, activating better isoforms I, IV, VA, VII, and XIV."
Temperini C. , Innocenti A. , Scozzafava A. , Mastrolorenzo A. , Supuran C.T.
Bioorg. Med. Chem. Lett.17:628-635(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
12.

"A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases."
Crocetti L. , Maresca A. , Temperini C. , Hall R.A. , Scozzafava A. , Muehlschlegel F.A. , Supuran C.T.
Bioorg. Med. Chem. Lett.19:1371-1375(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
13.

"Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors."
Maresca A. , Temperini C. , Vu H. , Pham N.B. , Poulsen S.-A. , Scozzafava A. , Quinn R.J. , Supuran C.T.
J. Am. Chem. Soc.131:3057-3062(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ENZYME REGULATION
14.

"Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide."
Di Fiore A. , Monti S.M. , Hilvo M. , Parkkila S. , Romano V. , Scaloni A. , Pedone C. , Scozzafava A. , Supuran C.T. , De Simone G.
Proteins74:164-175(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION
15.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
16.

"Structure of human carbonic anhydrase B. I. Crystallization and heavy atom modifications."
Kannan K.K. , Fridborg K. , Bergsten P.C. , Liljas A. , Loevgren S. , Petef M. , Strandberg B. , Waara I. , Adler L. , Falkbring S.O. , Goethe P.O. , Nyman P.O.
J. Mol. Biol.63:601-604(1972) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260
17.

"Crystal structure of human erythrocyte carbonic anhydrase B. Three-dimensional structure at a nominal 2.2-A resolution."
Kannan K.K. , Notstrand B. , Fridborg K. , Loevgren S. , Ohlsson A. , Petef M.
Proc. Natl. Acad. Sci. U.S.A.72:51-55(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)
18.

"Structure, refinement, and function of carbonic anhydrase isozymes: refinement of human carbonic anhydrase I."
Kannan K.K. , Ramanadham M. , Jones T.A.
Ann. N. Y. Acad. Sci.429:49-60(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION
19.

"Differences in anionic inhibition of human carbonic anhydrase I revealed from the structures of iodide and gold cyanide inhibitor complexes."
Kumar V. , Kannan K.K. , Sathyamurthi P.
Acta Crystallogr. D50:731-738(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND INHIBITORS
20.

"Enzyme-substrate interactions. Structure of human carbonic anhydrase I complexed with bicarbonate."
Kumar V. , Kannan K.K.
J. Mol. Biol.241:226-232(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.60 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND BICARBONATE
21.

"Drug-protein interactions. Refined structures of three sulfonamide drug complexes of human carbonic anhydrase I enzyme."
Chakravarty S. , Kannan K.K.
J. Mol. Biol.243:298-309(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND INHIBITORS
22.

"Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination."
Ferraroni M. , Tilli S. , Briganti F. , Chegwidden W.R. , Supuran C.T. , Wiebauer K.E. , Tashian R.E. , Scozzafava A.
Biochemistry41:6237-6244(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION;VARIANT MICHIGAN-1 ARG-68
23.

"Carbonic anhydrase activators: the first X-ray crystallographic study of an adduct of isoform I."
Temperini C. , Scozzafava A. , Supuran C.T.
Bioorg. Med. Chem. Lett.16:5152-5156(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND ACTIVATORS;ACTIVATION BY IMIDAZOLE AND HISTIDINE
24.

"Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with 'two-prong' inhibitors reveal the molecular basis of high affinity."
Jude K.M. , Banerjee A.L. , Haldar M.K. , Manokaran S. , Roy B. , Mallik S. , Srivastava D.K. , Christianson D.W.
J. Am. Chem. Soc.128:3011-3018(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND INHIBITORS;ENZYME REGULATION
25.

"Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I."
Temperini C. , Innocenti A. , Guerri A. , Scozzafava A. , Rusconi S. , Supuran C.T.
Bioorg. Med. Chem. Lett.17:2210-2215(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS) OF 6-260 IN COMPLEX WITH ZINC ION AND THE ANTIVIRAL FOSCARNET;ENZYME REGULATION
26.

"Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II."
Srivastava D.K. , Jude K.M. , Banerjee A.L. , Haldar M. , Manokaran S. , Kooren J. , Mallik S. , Christianson D.W.
J. Am. Chem. Soc.129:5528-5537(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.55 ANGSTROMS) OF 2-260 IN COMPLEX WITH ZINC ION AND INHIBITORS;ENZYME REGULATION
27.

"Population genetic studies of the Philippine Negritos. III. Identification of the carbonic anhydrase-1 variant with CA1 Guam."
Omoto K. , Ueda S. , Goriki K. , Takahashi N. , Misawa S. , Pagaran I.G.
Am. J. Hum. Genet.33:105-111(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT GUAM ARG-254
28.

"Marked zinc activation of ester hydrolysis by a mutation, 67-His (CAT) to Arg (CGT), in the active site of human carbonic anhydrase I."
Chegwidden W.R. , Wagner L.E. , Venta P.J. , Bergenhem N.C.H. , Yu Y.-S.L. , Tashian R.E.
Hum. Mutat.4:294-296(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MICHIGAN-1 ARG-68

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