Casp1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comCasp1 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Casp1(Gene name) > Rat

Casp1 (Gene name),

Caspase-1 (Protein name ), CASP1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (1)

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Gene name:

Casp1(Il1bc;Il1bce);

Protein name:

Caspase-1(CASP-1);

Alternative:

Interleukin-1 beta-converting enzyme(ICE;IL-1 beta-converting enzyme);Interleukin-1 beta convertase(IL-1BC);p45;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Heterotetramer that consists of two anti-parallel arranged heterodimers, each one formed bya 20 kDa (p20) and a 10 kDa (p10) subunit. The p20 subunit can also form a heterodimer with the epsilon isoform which then has an inhibitory effect. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and NALP2 and whose function would be the activation of proinflammatory caspases. Interacts with CARD17/INCA and CARD18.

Function:

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

402

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

402:

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

P43527

STRING:

10116.ENSRNOP00000009993

UniGene:

Rn.37508

Pfam:

PF00619

SMR:

P43527

Uniprot:

P43527

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ELISA Kit for Rat CASP-1

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E1592d

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96T

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ELISA Kit for Rat CASP-1

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E1592r

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ELISA Kit for Rat CASP-1

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E1592h

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ELISA Kit for Rat CASP-1

Cat.:

E1592m

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96T

ELISA Kit for Rat CASP-1

Cat.:

E1592p

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96T

CLIA Kit for Rat CASP-1

Cat.:

U1592d

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96T

CLIA Kit for Rat CASP-1

Cat.:

U1592p

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat CASP-1

Cat.:

U1592m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Rat CASP-1

Cat.:

U1592h

Price:

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Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Rat CASP-1

Cat.:

U1592r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat CASP-1

Cat.:

P1592Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat CASP-1

Cat.:

P1592Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat CASP-1

Cat.:

P1592Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rat CASP-1

Monoclonal Antibody for Rat CASP-1

Protein for Rat CASP-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain of Adult Offspring Rats: Involvement of the NLRP3 Inflammasome-Related Pathway"

E Trojan, K Chamera, N Bryniarska, et al.

From:Molecular Neurobiology

References

1.

"Cloning, tissue expression and regulation of rat interleukin 1 beta converting enzyme."
Keane K.M. , Giegel D.A. , Lipinski W.J. , Callahan M.J. , Shivers B.D.
Cytokine7:105-110(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Spleen.
2.

"Interleukin-1 beta-converting enzyme-related proteases (IRPs) and mammalian cell death: dissociation of IRP-induced oligonucleosomal endonuclease activity from morphological apoptosis in granulosa cells of the ovarian follicle."
Flaws J.A. , Kugu K. , Trbovich A.M. , Desanti A. , Tilly K.I. , Hirshfield A.N. , Tilly J.L.
Endocrinology136:5042-5053(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 228-362
tissue: Ovary.

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