CASP14 ELISA Kit for Human(Homo sapiens) | EIAab.comCASP14 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CASP14(Gene name) > Human

CASP14 (Gene name),

Caspase-14 (Protein name ), CASPE_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CASP14;

Protein name:

Caspase-14(CASP-14);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Complex of unprocessed caspase-14 and processed 19 kDa (p19) and 10 kDa (p10) subunits.

Function:

Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin.

Subcellular Location:

Cytoplasm Nucleus

Protein Attributes:

Sequence length:

242

Sequence:

50:

100:

150:

200:

242:

HILELLTEVT | RRMAEAELVQ | EGKARKTNPE | IQSTLRKRLY | LQ

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Hs.466057

String:

P31944

STRING:

9606.ENSP00000221740

Pfam:

PF00656

MIM:

605848

KEGG:

hsa:23581

SMR:

P31944

Uniprot:

P31944

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ELISA Kit for Human CASP-14

Cat.:

E2284h

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Packing:

96T

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ELISA Kit for Human CASP-14

Cat.:

E2284m

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MSDS:

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Packing:

96T

CLIA Kit for Human CASP-14

Cat.:

U2284h

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Manual:

Looking for manual.

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Packing:

96T

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CLIA Kit for Human CASP-14

Cat.:

U2284m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human CASP-14

Cat.:

P2284Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CASP-14

Cat.:

P2284Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human CASP-14

Protein for Human CASP-14

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Caspase-14: analysis of gene structure and mRNA expression during keratinocyte differentiation."
Eckhart L. , Ban J. , Fischer H. , Tschachler E.
Biochem. Biophys. Res. Commun.277:655-659(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Expression and transcriptional regulation of caspase-14 in simple and complex epithelia."
Pistritto G. , Jost M. , Srinivasula S.M. , Baffa R. , Poyet J.-L. , Kari C. , Lazebnik Y. , Rodeck U. , Alnemri E.S.
Cell Death Differ.9:995-1006(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Rasmussen H.H. , van Damme J. , Puype M. , Gesser B. , Celis J.E. , Vandekerckhove J.
Electrophoresis13:960-969(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 68-74; 137-147 AND 154-162
tissue: Keratinocyte.
5.

"Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing."
Lippens S. , Kockx M. , Knaapen M. , Mortier L. , Polakowska R. , Verheyen A. , Garmyn M. , Zwijsen A. , Formstecher P. , Huylebroeck D. , Vandenabeele P. , Declercq W.
Cell Death Differ.7:1218-1224(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION
6.

"Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation."
Chien A.J. , Presland R.B. , Kuechle M.K.
Biochem. Biophys. Res. Commun.296:911-917(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 153-163;PROTEOLYTIC PROCESSING;SUBUNIT;SUBCELLULAR LOCATION

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