Protein name:
Caveolin-1 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Homooligomer. Interacts with GLIPR2, SNAP25 and syntaxin. Interacts (via the N-terminus) with DPP4; the interaction is direct. Interacts with BMX, BTK, CTNNB1, CDH1, JUP and NOSTRIN.
Function:
Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.
Subcellular Location:
Golgi apparatus membrane
Peripheral membrane protein
Cell membrane
Peripheral membrane protein
Membrane
caveola
Peripheral membrane protein
Membrane raft
Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.
Protein Attributes:
50:
MSGGKYVDSE | GHLYTVPIRE | QGNIYKPNNK | AMAEEMNEKQ | VYDAHTKEID |
100:
LVNRDPKHLN | DDVVKIDFED | VIAEPEGTHS | FDGIWKASFT | TFTVTKYWFY |
150:
RLLSALFGIP | MALIWGIYFA | ILSFLHIWAV | VPCIKSFLIE | IQCISRVYSI |
178:
YVHTFCDPLF | EAIGKIFSNI | RINTQKEI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Bovine
Mouse
Pig
Chicken
Rabbit
Dog
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
ELISA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
CLIA Kit for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Polyclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Monoclonal Antibody for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
Protein for Bovine Caveolin-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
M H Wrobel, J Mlynarczuk.
References
1.
"Cloning and characterization of the cDNA encoding bovine caveolin-1."
Venema R.C.
Submitted (1997-02) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Aorta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
"Comparative analyses of multi-species sequences from targeted genomic regions."
Thomas J.W.
,
Touchman J.W.
,
Blakesley R.W.
,
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,
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,
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Wiggins L.S.
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Green E.D.
more...
Nature424:788-793(2003)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]