CPM ELISA Kit for Human(Homo sapiens) | EIAab.comCPM ELISA Kit for Human(Homo sapiens) | EIAab.com

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CPM (Gene name),

Carboxypeptidase M (Protein name ), CBPM_HUMAN from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Citations (2)

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Gene name:

CPM;

Protein name:

Carboxypeptidase M(CPM);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

N/A

Function:

Specifically removes C-terminal basic residues (Arg or Lys) from peptides and proteins. It is believed to play important roles in the control of peptide hormone and growth factor activity at the cell surface, and in the membrane-localized degradation of extracellular proteins.

Subcellular Location:

Cell membrane Lipid-anchor GPI-anchor

Protein Attributes:

Sequence length:

443

Sequence:

50:

MDFPCLWLGL | LLPLVAALDF | NYHRQEGMEA | FLKTVAQNYS | SVTHLHSIGK |

100:

SVKGRNLWVL | VVGRFPKEHR | IGIPEFKYVA | NMHGDETVGR | ELLLHLIDYL |

150:

VTSDGKDPEI | TNLINSTRIH | IMPSMNPDGF | EAVKKPDCYY | SIGRENYNQY |

200:

DLNRNFPDAF | EYNNVSRQPE | TVAVMKWLKT | ETFVLSANLH | GGALVASYPF |

250:

DNGVQATGAL | YSRSLTPDDD | VFQYLAHTYA | SRNPNMKKGD | ECKNKMNFPN |

300:

GVTNGYSWYP | LQGGMQDYNY | IWAQCFEITL | ELSCCKYPRE | EKLPSFWNNN |

350:

KASLIEYIKQ | VHLGVKGQVF | DQNGNPLPNV | IVEVQDRKHI | CPYRTNKYGE |

400:

YYLLLLPGSY | IINVTVPGHD | PHITKVIIPE | KSQNFSALKK | DILLPFQGQL |

443:

DSIPVSNPSC | PMIPLYRNLP | DHSAATKPSL | FLFLVSLLHI | FFK

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

MIM:

String:

UniGene:

Pfam:

SMR:

STRING:

9606.ENSP00000339157

KEGG:

Uniprot:

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ELISA Kit for Human CPM

Cat.:

E1456h

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Human CPM

Cat.:

E1456m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CPM

Cat.:

U1456h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human CPM

Cat.:

U1456m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human CPM

Cat.:

P1456Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human CPM

Cat.:

P1456Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human CPM

Monoclonal Antibody for Human CPM

Protein for Human CPM

Protein for Human CPM

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Recovery

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Linearity

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Citations

[1].

"Prevalence of impaired fasting glucose and analysis of risk factors in Han adolescents"

Qiang Lu, Fu-Zai Yin, Chun-Ming Ma, , Bo-Wei Liu, Dong-Hui Lou, Rui Wang, Guang-Fei Wu, Gai-Ling Han, Yi Shen, Bo Liu, Chun-Mei Qin

From:Journal of Diabetes and Its Complications

[2].

"Coexistence of non-alcoholic fatty liver disease with elevated alanine aminotransferase is associated with insulin resistance in young Han males"

R Wang, Q Lu, J Feng, et al.

References

1.

"Molecular cloning and sequencing of the cDNA for human membrane-bound carboxypeptidase M. Comparison with carboxypeptidases A, B, H, and N."
Tan F. , Chan S.J. , Steiner D.F. , Schilling J.W. , Skidgel R.A.
J. Biol. Chem.264:13165-13170(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 18-48
tissue: Placenta.
2.

Skidgel R.A.
Submitted (1999-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"Type 2 diabetes locus on 12q15: further mapping and mutation screening of two candidate genes."
Bektas A. , Hughes J.N. , Warram J.H. , Krolewski A.S. , Doria A.
Diabetes50:204-208(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"Molecular structure and alternative splicing of the human carboxypeptidase M gene."
Pessoa L.G. , Guerreiro da S.I. , Baptista H.A. , Pesquero J.L. , Paiva A.C.M. , Bader M. , Pesquero J.B.
Biol. Chem.383:263-269(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
5.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lung.
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Placenta.
7.

"Effect of mutation of two critical glutamic acid residues on the activity and stability of human carboxypeptidase M and characterization of its signal for glycosylphosphatidylinositol anchoring."
Tan F. , Balsitis S. , Black J.K. , Bloechl A. , Mao J.-F. , Becker R.P. , Schacht D. , Skidgel R.A.
Biochem. J.370:567-578(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 18-21;GPI-ANCHOR AT SER-423;BIOPHYSICOCHEMICAL PROPERTIES;FUNCTION;SUBCELLULAR LOCATION;IDENTIFICATION BY MASS SPECTROMETRY;MUTAGENESIS OF GLU-277; GLU-281 AND SER-423
8.

"Proteomic analysis of glycosylphosphatidylinositol-anchored membrane proteins."
Elortza F. , Nuehse T.S. , Foster L.J. , Stensballe A. , Peck S.C. , Jensen O.N.
Mol. Cell. Proteomics2:1261-1270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
9.

"Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment."
Elortza F. , Mohammed S. , Bunkenborg J. , Foster L.J. , Nuehse T.S. , Brodbeck U. , Peck S.C. , Jensen O.N.
J. Proteome Res.5:935-943(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GPI-ANCHOR [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-115 AND ASN-164
tissue: Liver.
11.

"Crystal structure of human carboxypeptidase M, a membrane-bound enzyme that regulates peptide hormone activity."
Reverter D. , Maskos K. , Tan F. , Skidgel R.A. , Bode W.
J. Mol. Biol.338:257-269(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 18-443;DISULFIDE BONDS;GLYCOSYLATION AT ASN-38 AND ASN-115

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