C-C motif chemokine 16 (Protein name
), CCL16_HUMAN from NCBI database.
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Gene name:
CCL16(ILINCK;NCC4;SCYA16);
Protein name:
C-C motif chemokine 16;
Alternative:
Chemokine LEC;Chemokine CC-4(HCC-4);LCC-1;IL-10-inducible chemokine;Lymphocyte and monocyte chemoattractant(LMC);Liver-expressed chemokine;NCC-4;Monotactin-1(MTN-1);Small-inducible cytokine A16;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
N/A
Function:
Shows chemotactic activity for lymphocytes and monocytes but not neutrophils. Also shows potent myelosuppressive activity, suppresses proliferation of myeloid progenitor cells. Recombinant SCYA16 shows chemotactic activity for monocytes and THP-1 monocytes, but not for resting lymphocytes and neutrophils. Induces a calcium flux in THP-1 cells that were desensitized by prior expression to RANTES.
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Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF N-TERMINUS