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Index > Protein center > CCL19(Gene name) > Human
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  • CCL19 (Gene name),
  • C-C motif chemokine 19 (Protein name ),  CCL19_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCL19(ELC;MIP3B;SCYA19);
    Protein name:
    C-C motif chemokine 19;
    Alternative:
    CK beta-11;Beta-chemokine exodus-3;Macrophage inflammatory protein 3 beta(MIP-3-beta);Epstein-Barr virus-induced molecule 1 ligand chemokine(EBI1 ligand chemokine;ELC);Small-inducible cytokine A19;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    98
    Sequence:
    50:
    MALLLALSLL | VLWTSPAPTL | SGTNDAEDCC | LSVTQKPIPG | YIVRNFHYLL | 
    98:
    IKDGCRVPAV | VFTTLRGRQL | CAPPDQPWVE | RIIQRLQRTS | AKMKRRSS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C motif chemokine 19
    Cat.:
    E0096h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human C-C motif chemokine 19
    Cat.:
    E0096m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 19
    Cat.:
    U0096m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 19
    Cat.:
    U0096h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human C-C motif chemokine 19
    Cat.:
    P0096Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human C-C motif chemokine 19
    Cat.:
    P0096Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C motif chemokine 19
    Monoclonal Antibody for Human C-C motif chemokine 19
    Protein for Human C-C motif chemokine 19
    Protein for Human C-C motif chemokine 19

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification through bioinformatics of two new macrophage proinflammatory human chemokines: MIP-3alpha and MIP-3beta."
      Rossi D.L. , Vicari A.P. , Franz-Bacon K. , McClanahan T.K. , Zlotnik A.
      J. Immunol.158:1033-1036(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7."
      Yoshida R. , Imai T. , Hieshima K. , Kusuda J. , Baba M. , Kitaura M. , Nishimura M. , Kakizaki M. , Nomiyama H. , Yoshie O.
      J. Biol. Chem.272:13803-13809(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
      tissue: Fetal lung.
    3. 3.
      "DCCL chemokines represent a novel beta chemokine subfamily."
      Hromas R.A. , Gray P. , Klemsz M. , Fife K. , Broxmeyer H.
      Submitted (1998-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      Reiterer P. , Bernhardt G. , Lipp M.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Pancreas.
      tissue: Spleen.
    6. 6.
      "CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cells."
      Kim C.H. , Pelus L.M. , White J.R. , Applebaum E. , Johanson K. , Broxmeyer H.E.
      J. Immunol.160:2418-2424(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Beta-arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR."
      Watts A.O. , Verkaar F. , van der Lee M.M. , Timmerman C.A. , Kuijer M. , van Offenbeek J. , van Lith L.H. , Smit M.J. , Leurs R. , Zaman G.J. , Vischer H.F.
      J. Biol. Chem.288:7169-7181(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RECEPTOR INTERACTION
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