Gene name:
CCL19 (ELC;MIP3B;SCYA19) ;
Protein name:
C-C motif chemokine 19 ;
Alternative:
CK beta-11 ;Beta-chemokine exodus-3 ;Macrophage inflammatory protein 3 beta (MIP-3-beta) ;Epstein-Barr virus-induced molecule 1 ligand chemokine (EBI1 ligand chemokine;ELC) ;Small-inducible cytokine A19 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Specifically binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes.
Subcellular Location:
Secreted
Protein Attributes:
50:
MALLLALSLL | VLWTSPAPTL | SGTNDAEDCC | LSVTQKPIPG | YIVRNFHYLL |
98:
IKDGCRVPAV | VFTTLRGRQL | CAPPDQPWVE | RIIQRLQRTS | AKMKRRSS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human C-C motif chemokine 19
ELISA Kit for Human C-C motif chemokine 19
CLIA Kit for Human C-C motif chemokine 19
CLIA Kit for Human C-C motif chemokine 19
Polyclonal Antibody for Human C-C motif chemokine 19
Polyclonal Antibody for Human C-C motif chemokine 19
Monoclonal Antibody for Human C-C motif chemokine 19
Monoclonal Antibody for Human C-C motif chemokine 19
Protein for Human C-C motif chemokine 19
Protein for Human C-C motif chemokine 19
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
"Molecular cloning of a novel human CC chemokine EBI1-ligand chemokine that is a specific functional ligand for EBI1, CCR7."
Yoshida R.
,
Imai T.
,
Hieshima K.
,
Kusuda J.
,
Baba M.
,
Kitaura M.
,
Nishimura M.
,
Kakizaki M.
,
Nomiyama H.
,
Yoshie O.
J. Biol. Chem.272:13803-13809(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PARTIAL PROTEIN SEQUENCE
tissue :
Fetal lung .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Pancreas .
tissue :
Spleen .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
7.
"Beta-arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR."
Watts A.O.
,
Verkaar F.
,
van der Lee M.M.
,
Timmerman C.A.
,
Kuijer M.
,
van Offenbeek J.
,
van Lith L.H.
,
Smit M.J.
,
Leurs R.
,
Zaman G.J.
,
Vischer H.F.
J. Biol. Chem.288:7169-7181(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : RECEPTOR INTERACTION