CCL21 ELISA Kit for Human(Homo sapiens) | EIAab.comCCL21 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CCL21(Gene name) > Human

CCL21 (Gene name),

C-C motif chemokine 21 (Protein name ), CCL21_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CCL21(UNQ784/PRO1600;SCYA21);

Protein name:

C-C motif chemokine 21;

Alternative:

Beta-chemokine exodus-2;6Ckine;Small-inducible cytokine A21;Secondary lymphoid-tissue chemokine(SLC);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Binds to CCR7.

Function:

Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

134

Sequence:

50:

100:

134:

QGCRKDRGAS | KTGKKGKGSK | GCKRTERSQT | PKGP

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:6366

SMR:

O00585

Pfam:

PF00048

MIM:

602737

String:

O00585

STRING:

9606.ENSP00000259607

UniGene:

Hs.57907

Uniprot:

O00585

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ELISA Kit for Human C-C motif chemokine 21

Cat.:

E1575h

Price:

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Manual:

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MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human C-C motif chemokine 21

Cat.:

U1575h

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human C-C motif chemokine 21

Cat.:

P1575Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human C-C motif chemokine 21

Protein for Human C-C motif chemokine 21

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning of a novel human CC chemokine secondary lymphoid-tissue chemokine that is a potent chemoattractant for lymphocytes and mapped to chromosome 9p13."
Nagira M. , Imai T. , Hieshima K. , Kusuda J. , Ridanpaeae M. , Takagi S. , Nishimura M. , Kakizaki M. , Nomiyama H. , Yoshie O.
J. Biol. Chem.272:19518-19524(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Identification and characterization of a novel beta chemokine containing six conserved cysteines."
Hedrick J.A. , Zlotnik A.
J. Immunol.159:1589-1593(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Isolation and characterization of Exodus-2, a novel C-C chemokine with a unique 37-amino acid carboxyl-terminal extension."
Hromas R. , Kim C.H. , Klemsz M. , Krathwohl M. , Fife K. , Cooper S. , Schnizlein-Bick C. , Broxmeyer H.E.
J. Immunol.159:2554-2558(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 24-33
4.

"A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes."
Gunn M.D. , Tangemann K. , Tam C. , Cyster J.G. , Rosen S.D. , Williams L.T.
Proc. Natl. Acad. Sci. U.S.A.95:258-263(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];CHARACTERIZATION
5.

"Genomic organisation of human SLC."
Reiterer P. , Bernhardt G. , Lipp M.
Submitted (1998-04) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Pancreas.
tissue: Spleen.
8.

"Secondary lymphoid-tissue chemokine is a functional ligand for the CC chemokine receptor CCR7."
Yoshida R. , Nagira M. , Kitaura M. , Imagawa N. , Imai T. , Yoshie O.
J. Biol. Chem.273:7118-7122(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RECEPTOR INTERACTION
9.

"Beta-arrestin recruitment and G protein signaling by the atypical human chemokine decoy receptor CCX-CKR."
Watts A.O. , Verkaar F. , van der Lee M.M. , Timmerman C.A. , Kuijer M. , van Offenbeek J. , van Lith L.H. , Smit M.J. , Leurs R. , Zaman G.J. , Vischer H.F.
J. Biol. Chem.288:7169-7181(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: RECEPTOR INTERACTION
10.

"Solution structure of CCL21 and identification of a putative CCR7 binding site."
Love M. , Sandberg J.L. , Ziarek J.J. , Gerarden K.P. , Rode R.R. , Jensen D.R. , McCaslin D.R. , Peterson F.C. , Veldkamp C.T.
Biochemistry51:733-735(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 24-134;SUBUNIT;DISULFIDE BONDS

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