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Index > Protein center > CCL23(Gene name) > Human
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  • CCL23 (Gene name),
  • C-C motif chemokine 23 (Protein name ),  CCL23_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    CCL23(MIP3;MPIF1;SCYA23);
    Protein name:
    C-C motif chemokine 23;
    Alternative:
    Macrophage inflammatory protein 3(MIP-3);CK-beta-8(CKB-8);Small-inducible cytokine A23;Myeloid progenitor inhibitory factor 1(MPIF-1);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Shows chemotactic activity for monocytes, resting T-lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    120
    Sequence:
    50:
    MKVSVAALSC | LMLVTALGSQ | ARVTKDAETE | FMMSKLPLEN | PVLLDRFHAT | 
    100:
    SADCCISYTP | RSIPCSLLES | YFETNSECSK | PGVIFLTKKG | RRFCANPSDK | 
    120:
    QVQVCVRMLK | LDTRIKTRKN | 
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    MIM:
    UniGene:
    Pfam:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human C-C motif chemokine 23
    Cat.:
    E1574h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human C-C motif chemokine 23
    Cat.:
    U1574h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human C-C motif chemokine 23
    Cat.:
    P1574Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human C-C motif chemokine 23
    Protein for Human C-C motif chemokine 23

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Macrophage inflammatory protein-3 and -4."
      Li H. , Ruben S.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT MET-106
    2. 2.
      "Molecular and functional characterization of two novel human C-C chemokines as inhibitors of two distinct classes of myeloid progenitors."
      Patel V.P. , Kreider B.L. , Li Y. , Li H. , Leung K. , Salcedo T. , Nardelli B. , Pippalla V. , Gentz S. , Thotakura R. , Parmelee D. , Gentz R. , Garotta G.
      J. Exp. Med.185:1163-1172(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT);PROTEIN SEQUENCE OF 22-36;VARIANT MET-106
      tissue: Aortic endothelium.
    3. 3.
      "Characterization of CKbeta8 and CKbeta8-1: two alternatively spliced forms of human beta-chemokine, chemoattractants for neutrophils, monocytes, and lymphocytes, and potent agonists at CC chemokine receptor 1."
      Youn B.-S. , Zhang S.M. , Broxmeyer H.E. , Cooper S. , Antol K. , Fraser M. Jr. , Kwon B.S.
      Blood91:3118-3126(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS SHORT AND LONG);ALTERNATIVE SPLICING;VARIANT MET-106
      tissue: Monocyte.
    4. 4.
      "Organization of the chemokine gene cluster on human chromosome 17q11.2 containing the genes for CC chemokine MPIF-1, HCC-2, LEC, and RANTES."
      Nomiyama H. , Fukuda S. , Iio M. , Tanase S. , Miura R. , Yoshie O.
      J. Interferon Cytokine Res.19:227-234(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];ALTERNATIVE SPLICING;VARIANT MET-106
    5. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT MET-106
    6. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS LONG AND SHORT);VARIANT MET-106
      tissue: Liver.
    7. 8.
      "The chemokine information source: identification and characterization of novel chemokines using the WorldWideWeb and expressed sequence tag databases."
      Wells T.N.C. , Peitsch M.C.
      J. Leukoc. Biol.61:545-550(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISCUSSION OF SEQUENCE
    8. 9.
      "Proteolytic activation of alternative CCR1 ligands in inflammation."
      Berahovich R.D. , Miao Z. , Wang Y. , Premack B. , Howard M.C. , Schall T.J.
      J. Immunol.174:7341-7351(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF CCL23(19-99); CCL23(22-99); CCL23(27-99) AND CCL23(30-99);PROTEOLYTIC PROCESSING OF N-TERMINUS;TISSUE SPECIFICITY;FUNCTION
    9. 10.
      "Solution structure and dynamics of myeloid progenitor inhibitory factor-1 (MPIF-1), a novel monomeric CC chemokine."
      Rajarathnam K. , Li Y. , Rohrer T. , Gentz R.
      J. Biol. Chem.276:4909-4916(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 45-120
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