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Index > Protein center > Ccl2(Gene name) > Mouse
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  • Ccl2 (Gene name),
  • C-C motif chemokine 2 (Protein name ),  CCL2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (2)
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  • Gene name:
    Ccl2(Je;Mcp1;Scya2);
    Protein name:
    C-C motif chemokine 2;
    Alternative:
    Monocyte chemotactic protein 1(MCP-1);Monocyte chemoattractant protein 1;Small-inducible cytokine A2;Platelet-derived growth factor-inducible protein JE;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Monomer or homodimer; in equilibrium.
    Function:
    Chemotactic factor that attracts monocytes, but not neutrophils.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    148
    Sequence:
    50:
    MQVPVMLLGL | LFTVAGWSIH | VLAQPDAVNA | PLTCCYSFTS | KMIPMSRLES | 
    100:
    YKRITSSRCP | KEAVVFVTKL | KREVCADPKK | EWVQTYIKNL | DRNQMRSEPT | 
    148:
    TLFKTASALR | SSAPLNVKLT | RKSEANASTT | FSTTTSSTSV | GVTSVTVN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    UniGene:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C motif chemokine 2
    MSDS:
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087m
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087b
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087r
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087p
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Mouse C-C motif chemokine 2
    Cat.:
    E0087d
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    MSDS:
    Please sign in first.
    Packing:
    96T
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    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087p
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C motif chemokine 2
    Cat.:
    U0087h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse C-C motif chemokine 2
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Cat.:
    P0087Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Polyclonal Antibody for Mouse C-C motif chemokine 2
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    P0087Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Polyclonal Antibody for Mouse C-C motif chemokine 2
    Cat.:
    P0087Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Monoclonal Antibody for Mouse C-C motif chemokine 2
    Protein for Mouse C-C motif chemokine 2
    Cat.:
    R0087b
    Price:
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    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse C-C motif chemokine 2
    Protein for Mouse C-C motif chemokine 2
    Cat.:
    R0087d
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse C-C motif chemokine 2
    Cat.:
    R0087p
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse C-C motif chemokine 2
    Cat.:
    R0087h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Mouse C-C motif chemokine 2
    Protein for Mouse C-C motif chemokine 2

    R&D Technical Data

    s

    12% SDS-PAGE analysis

             12% SDS-PAGE analysis

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤7.5%

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    Recovery

    Recovery was determined by spiking various levels of CCL2 into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    97

    91-99

    Plasma

    96

    94-103

     

     

     

     

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    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of CCL2 and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-98%

    96-103%

    97-105%

    102-108%

    EDTA plasma(n=5)

    96-101%

    98-105%

    99-106%

    91-96%

    heparin plasma(n=5)

    90-103%

     

    91-104%

    94-105%

    95-102%

     

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    References
    1. 1.
      "Platelet-derived growth factor-inducible gene JE is a member of a family of small inducible genes related to platelet factor 4."
      Kawahara R.S. , Deuel T.F.
      J. Biol. Chem.264:679-682(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties."
      Rollins B.J. , Morrison E.D. , Stiles C.D.
      Proc. Natl. Acad. Sci. U.S.A.85:3738-3742(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis."
      Teuscher C. , Butterfield R.J. , Ma R.Z. , Zachary J.F. , Doerge R.W. , Blankenhorn E.P.
      J. Immunol.163:2262-2266(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS GLY-50 AND GLN-92
      strain: B10.S/J.
      strain: BALB/c.
      strain: DBA/2J.
      strain: NOD/LtJ.
      strain: SJL/J.
      tissue: Spleen.
    4. 4.
      "Production and identification of natural monocyte chemotactic protein from virally infected murine fibroblasts. Relationship with the product of the mouse competence (JE) gene."
      van Damme J. , Decock B. , Bertini R. , Conings R. , Lenaerts J.-P. , Put W. , Opdenakker G. , Mantovani A.
      Eur. J. Biochem.199:223-229(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-42
    5. 5.
      "Fat-specific protein 27 modulates nuclear factor of activated T cells 5 and the cellular response to stress."
      Ueno M. , Shen W.J. , Patel S. , Greenberg A.S. , Azhar S. , Kraemer F.B.
      J. Lipid Res.54:734-743(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION BY OSMOTIC STRESS
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