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Index > Protein center > Ccl5(Gene name) > Mouse
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  • Ccl5 (Gene name),
  • C-C motif chemokine 5 (Protein name ),  CCL5_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Ccl5(Scya5);
    Protein name:
    C-C motif chemokine 5;
    Alternative:
    T-cell-specific protein RANTES;Small-inducible cytokine A5;MuRantes;SIS-delta;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    91
    Sequence:
    50:
    MKISAAALTI | ILTAAALCTP | APASPYGSDT | TPCCFAYLSL | ALPRAHVKEY | 
    91:
    FYTSSKCSNL | AVVFVTRRNR | QVCANPEKKW | VQEYINYLEM | S
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    Pfam:
    KEGG:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse C-C motif chemokine 5
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    E0116h
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    ELISA Kit for Mouse C-C motif chemokine 5
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    ELISA Kit for Mouse C-C motif chemokine 5
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    E0116p
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    ELISA Kit for Mouse C-C motif chemokine 5
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    E0116r
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    ELISA Kit for Mouse C-C motif chemokine 5
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    E0116b
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    ELISA Kit for Mouse C-C motif chemokine 5
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    E0116d
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    CLIA Kit for Mouse C-C motif chemokine 5
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    U0116h
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    CLIA Kit for Mouse C-C motif chemokine 5
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    CLIA Kit for Mouse C-C motif chemokine 5
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    CLIA Kit for Mouse C-C motif chemokine 5
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    CLIA Kit for Mouse C-C motif chemokine 5
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    CLIA Kit for Mouse C-C motif chemokine 5
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    Polyclonal Antibody for Mouse C-C motif chemokine 5
    Polyclonal Antibody for Mouse C-C motif chemokine 5
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    P0116Rb-m
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    Polyclonal Antibody for Mouse C-C motif chemokine 5
    Polyclonal Antibody for Mouse C-C motif chemokine 5
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    Polyclonal Antibody for Mouse C-C motif chemokine 5
    Polyclonal Antibody for Mouse C-C motif chemokine 5
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    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Monoclonal Antibody for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5
    Protein for Mouse C-C motif chemokine 5

    R&D Technical Data

        12% SDS-PAGE Analysis

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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤ 4.7%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤ 8.1%

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    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    97

    91-103

    Plasma

    98

    92-106

     

     

     

     

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    Linearity

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    92-102%

    90-103%

    93-104%

    92-106%

    EDTA plasma(n=5)

    89-97%

    92-101%

    93-99%

    90-102%

    heparin plasma(n=5)

    91-102%

     

    90-104%

    95-107%

    93-108%

     

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    References
    1. 1.
      "Isolation and characterization of cDNA from renal tubular epithelium encoding murine Rantes."
      Heeger P. , Wolf G. , Meyers C. , Sun M.J. , O'Farrell S.C. , Krensky A.M. , Neilson E.G.
      Kidney Int.41:220-225(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Molecular cloning and expression of the murine RANTES cytokine: structural and functional conservation between mouse and man."
      Schall T.J. , Simpson N.J. , Mak J.Y.
      Eur. J. Immunol.22:1477-1481(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Cloning, genomic organization, and chromosomal localization of the Scya5 gene encoding the murine chemokine RANTES."
      Danoff T.M. , Lalley P.A. , Chang Y.S. , Heeger P.S. , Neilson E.G.
      J. Immunol.152:1182-1189(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: NIH Swiss.
    4. 4.
      "Definition of a lipopolysaccharide-responsive element in the 5'-flanking regions of MuRantes and crg-2."
      Shin H.S. , Drysdale B.E. , Shin M.L. , Noble P.W. , Fisher S.N. , Paznekas W.A.
      Mol. Cell. Biol.14:2914-2925(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
    5. 5.
      "Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis."
      Teuscher C. , Butterfield R.J. , Ma R.Z. , Zachary J.F. , Doerge R.W. , Blankenhorn E.P.
      J. Immunol.163:2262-2266(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: B10.S/J.
      strain: BALB/cJ.
      strain: DBA/2J.
      strain: NOD/LtJ.
      strain: SJL/J.
      tissue: Spleen.
    6. 6.
      "Organization of the mouse CC chemokine cluster containing the genes for C10, MRP-2 and RANTES."
      Nomiyama H.
      Submitted (2000-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE
      strain: 129/Sv.
    7. 7.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Pancreas.
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Mammary gland.
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