CCR4 ELISA Kit for Human(Homo sapiens) | EIAab.comCCR4 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > CCR4(Gene name) > Human

CCR4 (Gene name),

C-C chemokine receptor type 4 (Protein name ), CCR4_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CCR4(CMKBR4);

Protein name:

C-C chemokine receptor type 4(C-C CKR-4;CC-CKR-4;CCR-4;CCR4);

Alternative:

K5-5;

CD:

CD194;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Function:

High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.

Subcellular Location:

Cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

360

Sequence:

50:

100:

150:

200:

250:

300:

350:

360:

TMDHDLHDAL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000332659

MIM:

604836

Pfam:

PF00001

KEGG:

hsa:1233

UniGene:

Hs.184926

SMR:

P51679

String:

P51679

Uniprot:

P51679

FOR

ELISA Kit for Human C-C CKR-4

Cat.:

E1920m

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96T

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ELISA Kit for Human C-C CKR-4

Cat.:

E1920h

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96T

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ELISA Kit for Human C-C CKR-4

Cat.:

E1920d

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Packing:

96T

CLIA Kit for Human C-C CKR-4

Cat.:

U1920h

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96T

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CLIA Kit for Human C-C CKR-4

Cat.:

U1920d

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96T

CLIA Kit for Human C-C CKR-4

Cat.:

U1920m

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96T

Polyclonal Antibody for Human C-C CKR-4

Cat.:

P1920Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human C-C CKR-4

Cat.:

P1920Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human C-C CKR-4

Monoclonal Antibody for Human C-C CKR-4

Protein for Human C-C CKR-4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Molecular cloning and functional expression of a novel CC chemokine receptor cDNA from a human basophilic cell line."
Power C.A. , Meyer A. , Nemeth K. , Bacon K.B. , Hoogewerf A.J. , Proudfoot A.E.I. , Wells T.N.C.
J. Biol. Chem.270:19495-19500(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Spleen.
2.

"New variations of human CC-chemokine receptors CCR3 and CCR4."
Kato H. , Tsuchiya N. , Izumi S. , Miyamasu M. , Nakajima T. , Kawasaki H. , Hirai K. , Tokunaga K.
Genes Immun.1:97-104(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS VAL-130 AND SER-178
3.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Kopatz S.A. , Aronstam R.S. , Sharma S.V.
Submitted (2003-06) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Blood.
5.

"The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4."
Imai T. , Baba M. , Nishimura M. , Kakizaki M. , Takagi S. , Yoshie O.
J. Biol. Chem.272:15036-15042(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4."
Imai T. , Chantry D. , Raport C.J. , Wood C.L. , Nishimura M. , Godiska R. , Yoshie O. , Gray P.W.
J. Biol. Chem.273:1764-1768(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
7.

"The chemokine receptor CCR4 in vascular recognition by cutaneous but not intestinal memory T cells."
Campbell J.J. , Haraldsen G. , Pan J. , Rottman J. , Qin S. , Ponath P. , Andrew D.P. , Warnke R. , Ruffing N. , Kassam N. , Wu L. , Butcher E.C.
Nature400:776-780(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309."
Inngjerdingen M. , Damaj B. , Maghazachi A.A.
J. Immunol.164:4048-4054(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;PHOSPHORYLATION

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