Gene name:
CD109 (CPAMD7) ;
Protein name:
CD109 antigen ;
Alternative:
C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7 ;150 kDa TGF-beta-1-binding protein ;p180 ;Platelet-specific Gov antigen ;r150 ;
CD:
CD109 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Heterodimer; disulfide-linked. Interacts with TGFB1 and TGFBR1. Forms a heteromeric complex with TGFBR1, TGFBR2 and TGFBR3 in a ligand-independent manner.
Function:
Modulates negatively TGFB1 signaling in keratinocytes.
Subcellular Location:
Cell membrane
Lipid-anchor
GPI-anchor
Protein Attributes:
50:
MQGPPLLTAA | HLLCVCTAAL | AVAPGPRFLV | TAPGIIRPGG | NVTIGVELLE |
100:
HCPSQVTVKA | ELLKTASNLT | VSVLEAEGVF | EKGSFKTLTL | PSLPLNSADE |
150:
IYELRVTGRT | QDEILFSNST | RLSFETKRIS | VFIQTDKALY | KPKQEVKFRI |
200:
VTLFSDFKPY | KTSLNILIKD | PKSNLIQQWL | SQQSDLGVIS | KTFQLSSHPI |
250:
LGDWSIQVQV | NDQTYYQSFQ | VSEYVLPKFE | VTLQTPLYCS | MNSKHLNGTI |
300:
TAKYTYGKPV | KGDVTLTFLP | LSFWGKKKNI | TKTFKINGSA | NFSFNDEEMK |
350:
NVMDSSNGLS | EYLDLSSPGP | VEILTTVTES | VTGISRNVST | NVFFKQHDYI |
400:
IEFFDYTTVL | KPSLNFTATV | KVTRADGNQL | TLEERRNNVV | ITVTQRNYTE |
450:
YWSGSNSGNQ | KMEAVQKINY | TVPQSGTFKI | EFPILEDSSE | LQLKAYFLGS |
500:
KSSMAVHSLF | KSPSKTYIQL | KTRDENIKVG | SPFELVVSGN | KRLKELSYMV |
550:
VSRGQLVAVG | KQNSTMFSLT | PENSWTPKAC | VIVYYIEDDG | EIISDVLKIP |
600:
VQLVFKNKIK | LYWSKVKAEP | SEKVSLRISV | TQPDSIVGIV | AVDKSVNLMN |
650:
ASNDITMENV | VHELELYNTG | YYLGMFMNSF | AVFQECGLWV | LTDANLTKDY |
700:
IDGVYDNAEY | AERFMEENEG | HIVDIHDFSL | GSSPHVRKHF | PETWIWLDTN |
750:
MGYRIYQEFE | VTVPDSITSW | VATGFVISED | LGLGLTTTPV | ELQAFQPFFI |
800:
FLNLPYSVIR | GEEFALEITI | FNYLKDATEV | KVIIEKSDKF | DILMTSNEIN |
850:
ATGHQQTLLV | PSEDGATVLF | PIRPTHLGEI | PITVTALSPT | ASDAVTQMIL |
900:
VKAEGIEKSY | SQSILLDLTD | NRLQSTLKTL | SFSFPPNTVT | GSERVQITAI |
950:
GDVLGPSING | LASLIRMPYG | CGEQNMINFA | PNIYILDYLT | KKKQLTDNLK |
1000:
EKALSFMRQG | YQRELLYQRE | DGSFSAFGNY | DPSGSTWLSA | FVLRCFLEAD |
1050:
PYIDIDQNVL | HRTYTWLKGH | QKSNGEFWDP | GRVIHSELQG | GNKSPVTLTA |
1100:
YIVTSLLGYR | KYQPNIDVQE | SIHFLESEFS | RGISDNYTLA | LITYALSSVG |
1150:
SPKAKEALNM | LTWRAEQEGG | MQFWVSSESK | LSDSWQPRSL | DIEVAAYALL |
1200:
SHFLQFQTSE | GIPIMRWLSR | QRNSLGGFAS | TQDTTVALKA | LSEFAALMNT |
1250:
ERTNIQVTVT | GPSSPSPVKF | LIDTHNRLLL | QTAELAVVQP | TAVNISANGF |
1300:
GFAICQLNVV | YNVKASGSSR | RRRSIQNQEA | FDLDVAVKEN | KDDLNHVDLN |
1350:
VCTSFSGPGR | SGMALMEVNL | LSGFMVPSEA | ISLSETVKKV | EYDHGKLNLY |
1400:
LDSVNETQFC | VNIPAVRNFK | VSNTQDASVS | IVDYYEPRRQ | AVRSYNSEVK |
1445:
LSSCDLCSDV | QGCRPCEDGA | SGSHHHSSVI | FIFCFKLLYF | MELWL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human CD109 antigen
ELISA Kit for Human CD109 antigen
CLIA Kit for Human CD109 antigen
CLIA Kit for Human CD109 antigen
Polyclonal Antibody for Human CD109 antigen
Polyclonal Antibody for Human CD109 antigen
Monoclonal Antibody for Human CD109 antigen
Monoclonal Antibody for Human CD109 antigen
Protein for Human CD109 antigen
Protein for Human CD109 antigen
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 86-98; 127-137; 170-183; 185-196; 355-374; 413-425; 444-451; 465-471; 478-491; 494-510; 573-589; 649-655; 666-672; 677-683; 698-709 AND 791-806;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;VARIANT MET-1241
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 22-50 (ISOFORM 1);TISSUE SPECIFICITY;VARIANTS SER-703; SER-797 AND ILE-845
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);PROTEIN SEQUENCE OF 173-191;FUNCTION;INTERACTION WITH TGFB1 AND TGFBR1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;PROTEOLYTIC CLEAVAGE;VARIANTS SER-703; SER-797 AND ILE-845
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANTS SER-703; SER-797 AND ILE-845
tissue :
Chondrocyte .
tissue :
Trachea .
tissue :
Vascular endothelial cell .
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANTS SER-703; SER-797; ILE-845 AND MET-1241
tissue :
Colon endothelium .
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 370-444 AND 922-959
8.
"A tyrosine703serine polymorphism of CD109 defines the Gov platelet alloantigens."
Schuh A.C.
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Blood99:1692-1698(2002)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 703-741;VARIANT GOV(B) SER-703
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEOLYTIC CLEAVAGE;GLYCOSYLATION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-68; ASN-118; ASN-247 AND ASN-419
tissue :
Plasma .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-247
tissue :
Platelet .
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-419
tissue :
Liver .
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-68 AND ASN-118
tissue :
Leukemic T-cell .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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more...
Science314:268-274(2006)
[
PubMed ]
[
Europe PMC ]
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Abstract ]
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Cited for : VARIANTS [LARGE SCALE ANALYSIS] GLU-1007 AND LYS-1065