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Index > Protein center > CD177(Gene name) > Human
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  • CD177 (Gene name),
  • CD177 antigen (Protein name ),  CD177_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    CD177(UNQ595/PRO1181;NB1;PRV1);
    Protein name:
    CD177 antigen;
    Alternative:
    NB1 glycoprotein(NB1 GP);Human neutrophil alloantigen 2a(HNA-2a);Polycythemia rubra vera protein 1(PRV-1);
    CD:
    CD177;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    N/A
    Subcellular Location:
    Cell membrane Lipid-anchor GPI-anchor
    Protein Attributes:
    Sequence length:
    437
    Sequence:
    50:
    MSAVLLLALL | GFILPLPGVQ | ALLCQFGTVQ | HVWKVSDLPR | QWTPKNTSCD | 
    100:
    SGLGCQDTLM | LIESGPQVSL | VLSKGCTEAK | DQEPRVTEHR | MGPGLSLISY | 
    150:
    TFVCRQEDFC | NNLVNSLPLW | APQPPADPGS | LRCPVCLSME | GCLEGTTEEI | 
    200:
    CPKGTTHCYD | GLLRLRGGGI | FSNLRVQGCM | PQPGCNLLNG | TQEIGPVGMT | 
    250:
    ENCNRKDFLT | CHRGTTIMTH | GNLAQEPTDW | TTSNTEMCEV | GQVCQETLLL | 
    300:
    LDVGLTSTLV | GTKGCSTVGA | QNSQKTTIHS | APPGVLVASY | THFCSSDLCN | 
    350:
    SASSSSVLLN | SLPPQAAPVP | GDRQCPTCVQ | PLGTCSSGSP | RMTCPRGATH | 
    400:
    CYDGYIHLSG | GGLSTKMSIQ | GCVAQPSSFL | LNHTRQIGIF | SAREKRDVQP | 
    437:
    PASQHEGGGA | EGLESLTWGV | GLALAPALWW | GVVCPSC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    MIM:
    UniGene:
    KEGG:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human CD177 antigen
    MSDS:
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    ELISA Kit for Human CD177 antigen
    Cat.:
    E15077h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human CD177 antigen
    Cat.:
    U15077h
    Price:
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human CD177 antigen
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Human CD177 antigen
    Polyclonal Antibody for Human CD177 antigen
    Monoclonal Antibody for Human CD177 antigen
    Monoclonal Antibody for Human CD177 antigen
    Protein for Human CD177 antigen
    Protein for Human CD177 antigen

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Cloning of PRV-1, a novel member of the uPAR receptor superfamily, which is overexpressed in polycythemia rubra vera."
      Temerinac S. , Klippel S. , Strunck E. , Roeder S. , Luebbert M. , Lange W. , Azemar M. , Meinhardt G. , Schaefer H.-E. , Pahl H.L.
      Blood95:2569-2576(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ILE-251;TISSUE SPECIFICITY;INDUCTION
    2. 2.
      "Molecular basis of the neutrophil glycoprotein NB1 (CD177) involved in the pathogenesis of immunenneutropenia and transfusion reactions."
      Kissel K. , Santoso S. , Hofmann C. , Stroncek D. , Bux J.
      Eur. J. Immunol.31:1301-1309(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PROTEIN SEQUENCE OF 35-45; 167-175 AND 386-393;VARIANTS PRO-3; PHE-119; ILE-251; GLN-323 AND SER-379;MASS SPECTROMETRY;GLYCOSYLATION
    3. 3.
      "Molecular basis of NB1 (HNA-2a, CD177) deficiency."
      Kissel K. , Scheffler S. , Kerowgan M. , Bux J.
      Blood99:4231-4233(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);VARIANT PRO-3
    4. 4.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ILE-251
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2004-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ILE-251
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS PRO-3 AND THR-348
      tissue: Colon.
    7. 7.
      "Signal peptide prediction based on analysis of experimentally verified cleavage sites."
      Zhang Z. , Henzel W.J.
      Protein Sci.13:2819-2824(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 22-36
    8. 8.
      "Biochemical characterization of PRV-1, a novel hematopoietic cell surface receptor, which is overexpressed in polycythemia rubra vera."
      Klippel S. , Strunck E. , Busse C.E. , Behringer D. , Pahl H.L.
      Blood100:2441-2448(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;GLYCOSYLATION;SHEDDING
    9. 9.
      "Overexpression of the polycythemia rubra vera-1 gene in essential thrombocythemia."
      Teofili L. , Martini M. , Luongo M. , Di Mario A. , Leone G. , De Stefano V. , Larocca L.M.
      J. Clin. Oncol.20:4249-4254(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION;TISSUE SPECIFICITY
    10. 10.
      "Lack of NB1 GP (CD177/HNA-2a) gene transcription in NB1 GP-neutrophils from NB1 GP-expressing individuals and association of low expression with NB1 gene polymorphisms."
      Wolff J. , Brendel C. , Fink L. , Bohle R.M. , Kissel K. , Bux J.
      Blood102:731-733(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-348;POLYMORPHISM
    11. 11.
      "CD177 polymorphisms: correlation between high-frequency single nucleotide polymorphisms and neutrophil surface protein expression."
      Caruccio L. , Walkovich K. , Bettinotti M. , Schuller R. , Stroncek D.
      Transfusion44:77-82(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PRO-3; PHE-119; GLN-323 AND SER-379
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