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Index > Protein center > CD34(Gene name) > Human
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  • CD34 (Gene name),
  • Hematopoietic progenitor cell antigen CD34 (Protein name ),  CD34_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    CD34;
    Protein name:
    Hematopoietic progenitor cell antigen CD34;
    Alternative:

    CD:
    CD34;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    385
    Sequence:
    50:
    MLVRRGARAG | PRMPRGWTAL | CLLSLLPSGF | MSLDNNGTAT | PELPTQGTFS | 
    100:
    NVSTNVSYQE | TTTPSTLGST | SLHPVSQHGN | EATTNITETT | VKFTSTSVIT | 
    150:
    SVYGNTNSSV | QSQTSVISTV | FTTPANVSTP | ETTLKPSLSP | GNVSDLSTTS | 
    200:
    TSLATSPTKP | YTSSSPILSD | IKAEIKCSGI | REVKLTQGIC | LEQNKTSSCA | 
    250:
    EFKKDRGEGL | ARVLCGEEQA | DADAGAQVCS | LLLAQSEVRP | QCLLLVLANR | 
    300:
    TEISSKLQLM | KKHQSDLKKL | GILDFTEQDV | ASHQSYSQKT | LIALVTSGAL | 
    350:
    LAVLGITGYF | LMNRRSWSPT | GERLGEDPYY | TENGGGQGYS | SGPGTSPEAQ | 
    385:
    GKASVNRGAQ | ENGTGQATSR | NGHSARQHVV | ADTEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    E1959h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    E1959d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    E1959m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    U1959h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    U1959m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    U1959d
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Polyclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    P1959Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Cat.:
    P1959Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Monoclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Monoclonal Antibody for Human Hematopoietic progenitor cell antigen CD34
    Protein for Human Hematopoietic progenitor cell antigen CD34
    Protein for Human Hematopoietic progenitor cell antigen CD34
    Protein for Human Hematopoietic progenitor cell antigen CD34

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular cloning of a cDNA encoding CD34, a sialomucin of human hematopoietic stem cells."
      Simmons D.L. , Satterthwaite A.B. , Tenen D.G. , Seed B.
      J. Immunol.148:267-271(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM CD34-F);PROTEIN SEQUENCE OF 32-43
      tissue: Bone marrow.
    2. 2.
      "Structure of the gene encoding CD34, a human hematopoietic stem cell antigen."
      Satterthwaite A.B. , Burn T.C. , le Beau M.M. , Tenen D.G.
      Genomics12:788-794(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM CD34-F)
    3. 3.
      "Two alternative forms of cDNA encoding CD34."
      Nakamura Y. , Komano H. , Nakauchi H.
      Exp. Hematol.21:236-242(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS CD34-F AND CD34-T)
      tissue: Megakaryoblast.
    4. 4.
      "Sequence analysis of the human CD34 antigen."
      Freund D. , Wiebe G.J. , Ehninger G. , Corbeil D.
      Submitted (2002-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM CD34-F)
      tissue: Heart.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM CD34-F)
      tissue: Placenta.
    6. 6.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM CD34-F)
      tissue: Skin.
    9. 9.
      "Structural and partial amino acid sequence analysis of the human hemopoietic progenitor cell antigen CD34."
      Sutherland D.R. , Watt S.M. , Dowden G. , Karhi K. , Baker M.A. , Greaves M.F. , Smart J.E.
      Leukemia2:793-803(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 32-47 AND 175-191;CHARACTERIZATION
    10. 10.
      "Activated protein kinase C directly phosphorylates the CD34 antigen on hematopoietic cells."
      Fackler M.J. , Civin C.I. , Sutherland D.R. , Baker M.A. , May W.S.
      J. Biol. Chem.265:11056-11061(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION BY PKC
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