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Index > Protein center > CD5(Gene name) > Human
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  • CD5 (Gene name),
  • T-cell surface glycoprotein CD5 (Protein name ),  CD5_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    CD5(LEU1);
    Protein name:
    T-cell surface glycoprotein CD5;
    Alternative:
    Lymphocyte antigen T1/Leu-1;
    CD:
    CD5;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Function:
    May act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    495
    Sequence:
    50:
    MPMGSLQPLA | TLYLLGMLVA | SCLGRLSWYD | PDFQARLTRS | NSKCQGQLEV | 
    100:
    YLKDGWHMVC | SQSWGRSSKQ | WEDPSQASKV | CQRLNCGVPL | SLGPFLVTYT | 
    150:
    PQSSIICYGQ | LGSFSNCSHS | RNDMCHSLGL | TCLEPQKTTP | PTTRPPPTTT | 
    200:
    PEPTAPPRLQ | LVAQSGGQHC | AGVVEFYSGS | LGGTISYEAQ | DKTQDLENFL | 
    250:
    CNNLQCGSFL | KHLPETEAGR | AQDPGEPREH | QPLPIQWKIQ | NSSCTSLEHC | 
    300:
    FRKIKPQKSG | RVLALLCSGF | QPKVQSRLVG | GSSICEGTVE | VRQGAQWAAL | 
    350:
    CDSSSARSSL | RWEEVCREQQ | CGSVNSYRVL | DAGDPTSRGL | FCPHQKLSQC | 
    400:
    HELWERNSYC | KKVFVTCQDP | NPAGLAAGTV | ASIILALVLL | VVLLVVCGPL | 
    450:
    AYKKLVKKFR | QKKQRQWIGP | TGMNQNMSFH | RNHTATVRSH | AENPTASHVD | 
    495:
    NEYSQPPRNS | HLSAYPALEG | ALHRSSMQPD | NSSDSDYDLH | GAQRL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    Pfam:
    MIM:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    E1798h
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    Packing:
    96T
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    ELISA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    E1798r
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    Packing:
    96T
    ELISA Kit for Human T-cell surface glycoprotein CD5
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    E1798m
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    Packing:
    96T
    ELISA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    E1798b
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    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    U1798b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    U1798r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    U1798m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human T-cell surface glycoprotein CD5
    Cat.:
    U1798h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human T-cell surface glycoprotein CD5
    Polyclonal Antibody for Human T-cell surface glycoprotein CD5
    Cat.:
    P1798Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD5
    Cat.:
    P1798Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human T-cell surface glycoprotein CD5
    Cat.:
    P1798Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human T-cell surface glycoprotein CD5
    Monoclonal Antibody for Human T-cell surface glycoprotein CD5
    Monoclonal Antibody for Human T-cell surface glycoprotein CD5
    Monoclonal Antibody for Human T-cell surface glycoprotein CD5
    Protein for Human T-cell surface glycoprotein CD5
    Protein for Human T-cell surface glycoprotein CD5
    Protein for Human T-cell surface glycoprotein CD5
    Protein for Human T-cell surface glycoprotein CD5

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    Precision
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    Linearity
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    References
    1. 1.
      "Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1."
      Jones N.H. , Clabby M.L. , Dialynas D.P. , Huag H.-J.S. , Herzenberg L.A. , Strominger J.L.
      Nature323:346-349(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANTS ARG-461 AND VAL-471
    2. 2.
      "Evolutionarily conserved transcription regulatory elements within the 5'-flanking region of the human CD5 gene."
      Calvo J. , Sole J. , Simarro M. , Vives J. , Lozano F.
      Tissue Antigens47:257-261(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-461 AND VAL-471
      tissue: Lymphocyte.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS ARG-461 AND VAL-471
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS LEU-224 AND ARG-461
      tissue: Thymus.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS ARG-461 AND VAL-471
      tissue: Pancreas.
    7. 7.
      "The B-cell surface protein CD72/Lyb-2 is the ligand for CD5."
      van de Velde H. , von Hoegen I. , Luo W. , Parnes J.R. , Thielemans K.
      Nature351:662-665(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD72/LYB-2
    8. 8.
      "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry."
      Salomon A.R. , Ficarro S.B. , Brill L.M. , Brinker A. , Phung Q.T. , Ericson C. , Sauer K. , Brock A. , Horn D.M. , Schultz P.G. , Peters E.C.
      Proc. Natl. Acad. Sci. U.S.A.100:443-448(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-439 AND SER-460;VARIANT [LARGE SCALE ANALYSIS] ARG-461;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    9. 9.
      "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry."
      Brill L.M. , Salomon A.R. , Ficarro S.B. , Mukherji M. , Stettler-Gill M. , Peters E.C.
      Anal. Chem.76:2763-2772(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-439;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    10. 10.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-453; SER-483 AND SER-485;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      "Crystal structure of the third extracellular domain of CD5 reveals the fold of a group B scavenger cysteine-rich receptor domain."
      Rodamilans B. , Munoz I.G. , Bragado-Nilsson E. , Sarrias M.R. , Padilla O. , Blanco F.J. , Lozano F. , Montoya G.
      J. Biol. Chem.282:12669-12677(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.21 ANGSTROMS) OF 270-369
    12. 12.
      "Three-dimensional solution structure and conformational plasticity of the N-terminal scavenger receptor cysteine-rich domain of human CD5."
      Garza-Garcia A. , Esposito D. , Rieping W. , Harris R. , Briggs C. , Brown M.H. , Driscoll P.C.
      J. Mol. Biol.378:129-144(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 25-134;DISULFIDE BONDS
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