Gene name:
CD63 (MLA1;TSPAN30) ;
Protein name:
CD63 antigen ;
Alternative:
Lysosomal-associated membrane protein 3 (LAMP-3) ;Granulophysin ;OMA81H ;Melanoma-associated antigen ME491 ;Tetraspanin-30 (Tspan-30) ;Ocular melanoma-associated antigen ;
CD:
CD63 ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Lysosome membrane
Multi-pass membrane protein
Late endosome membrane
Multi-pass membrane protein
Also found in Weibel-Palade bodies of endothelial cells. Located in platelet dense granules.
Protein Attributes:
50:
MAVEGGMKCV | KFLLYVLLLA | FCACAVGLIA | VGVGAQLVLS | QTIIQGATPG |
100:
SLLPVVIIAV | GVFLFLVAFV | GCCGACKENY | CLMITFAIFL | SLIMLVEVAA |
150:
AIAGYVFRDK | VMSEFNNNFR | QQMENYPKNN | HTASILDRMQ | ADFKCCGAAN |
200:
YTDWEKIPSM | SKNRVPDSCC | INVTVGCGIN | FNEKAIHKEG | CVEKIGGWLR |
238:
KNVLVVAAAA | LGIAFVEVLG | IVFACCLVKS | IRSGYEVM
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Rabbit
Human
Bovine
ELISA Kit for Human CD63 antigen
ELISA Kit for Human CD63 antigen
ELISA Kit for Human CD63 antigen
ELISA Kit for Human CD63 antigen
ELISA Kit for Human CD63 antigen
CLIA Kit for Human CD63 antigen
CLIA Kit for Human CD63 antigen
CLIA Kit for Human CD63 antigen
CLIA Kit for Human CD63 antigen
CLIA Kit for Human CD63 antigen
Polyclonal Antibody for Human CD63 antigen
Polyclonal Antibody for Human CD63 antigen
Polyclonal Antibody for Human CD63 antigen
Polyclonal Antibody for Human CD63 antigen
Polyclonal Antibody for Human CD63 antigen
Monoclonal Antibody for Human CD63 antigen
Monoclonal Antibody for Human CD63 antigen
Monoclonal Antibody for Human CD63 antigen
Monoclonal Antibody for Human CD63 antigen
Monoclonal Antibody for Human CD63 antigen
Protein for Human CD63 antigen
Protein for Human CD63 antigen
Protein for Human CD63 antigen
Protein for Human CD63 antigen
Protein for Human CD63 antigen
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Skeletal muscle .
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Wooden H.S.
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Wooden S.H.
,
Yen J.
,
Yoon L.
,
Yoon V.
,
Zorrilla S.E.
,
Nelson D.
,
Kucherlapati R.
,
Weinstock G.
,
Gibbs R.A.
more...
Nature440:346-351(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.
Mural R.J.
,
Istrail S.
,
Sutton G.G.
,
Florea L.
,
Halpern A.L.
,
Mobarry C.M.
,
Lippert R.
,
Walenz B.
,
Shatkay H.
,
Dew I.
,
Miller J.R.
,
Flanigan M.J.
,
Edwards N.J.
,
Bolanos R.
,
Fasulo D.
,
Halldorsson B.V.
,
Hannenhalli S.
,
Turner R.
,
Yooseph S.
,
Lu F.
,
Nusskern D.R.
,
Shue B.C.
,
Zheng X.H.
,
Zhong F.
,
Delcher A.L.
,
Huson D.H.
,
Kravitz S.A.
,
Mouchard L.
,
Reinert K.
,
Remington K.A.
,
Clark A.G.
,
Waterman M.S.
,
Eichler E.E.
,
Adams M.D.
,
Hunkapiller M.W.
,
Myers E.W.
,
Venter J.C.
more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
12.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Lung .
tissue :
Muscle .
13.
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Cited for : PROTEIN SEQUENCE OF 2-38 (ISOFORM 1);SUBCELLULAR LOCATION;LACK OF EXPRESSION IN HERMANSKY-PUDLAK SYNDROME
tissue :
Platelet .
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 2-21 (ISOFORMS 1/2)
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-130
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
18.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH TIMP1 AND ITGB1
19.
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Cited for : SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue :
Placenta .
20.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-130
tissue :
Liver .
21.
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Cited for : PALMITOYLATION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INTERACTION WITH CD9;IDENTIFICATION IN A COMPLEX WITH ITGB3
22.
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Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
23.
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Cited for : FUNCTION IN CELL-CELL ADHESION;SUBCELLULAR LOCATION
24.
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Cited for : FUNCTION IN MELANOCYTE DEVELOPMENT;SUBCELLULAR LOCATION;INTERACTION WITH PMEL
25.
"Tetraspanin CD63 promotes vascular endothelial growth factor receptor 2-beta1 integrin complex formation, thereby regulating activation and downstream signaling in endothelial cells in vitro and in vivo."
Tugues S.
,
Honjo S.
,
Konig C.
,
Padhan N.
,
Kroon J.
,
Gualandi L.
,
Li X.
,
Barkefors I.
,
Thijssen V.L.
,
Griffioen A.W.
,
Claesson-Welsh L.
J. Biol. Chem.288:19060-19071(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH KDR
26.
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Cited for : FUNCTION;INTERACTION WITH CD63 AND ITGB1