CD80 ELISA Kit for Human(Homo sapiens) | EIAab.comCD80 ELISA Kit for Human(Homo sapiens)

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CD80 (Gene name),

T-lymphocyte activation antigen CD80 (Protein name ), CD80_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CD80(CD28LG;CD28LG1;LAB7);

Protein name:

T-lymphocyte activation antigen CD80;

Alternative:

BB1;Activation B7-1 antigen;CTLA-4 counter-receptor B7.1(B7);

CD:

CD80;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with adenovirus subgroup B fiber proteins and acts as a receptor for these viruses.

Function:

Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

288

Sequence:

50:

100:

150:

200:

250:

288:

LISVNGIFVI | CCLTYCFAPR | CRERRRNERL | RRESVRPV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF08205

String:

P33681

KEGG:

hsa:941

SMR:

P33681

MIM:

112203

STRING:

9606.ENSP00000264246

UniGene:

Hs.838

Uniprot:

P33681

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ELISA Kit for Human T-lymphocyte activation antigen CD80

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ELISA Kit for Human T-lymphocyte activation antigen CD80

Cat.:

E2026h

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Manual:

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Packing:

96T

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ELISA Kit for Human T-lymphocyte activation antigen CD80

Cat.:

E2026m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human T-lymphocyte activation antigen CD80

Cat.:

U2026m

Price:

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Human T-lymphocyte activation antigen CD80

Cat.:

U2026h

Price:

Please sign in first.

Manual:

Looking for manual.

MSDS:

Please sign in first.

Packing:

96T

Range:

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CLIA Kit for Human T-lymphocyte activation antigen CD80

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Polyclonal Antibody for Human T-lymphocyte activation antigen CD80

Cat.:

P2026Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human T-lymphocyte activation antigen CD80

Cat.:

P2026Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human T-lymphocyte activation antigen CD80

Protein for Human T-lymphocyte activation antigen CD80

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"B7, a new member of the Ig superfamily with unique expression on activated and neoplastic B cells."
Freeman G.J. , Freedman A.S. , Segil J.M. , Lee G. , Whitman J.F. , Nadler L.M.
J. Immunol.143:2714-2722(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Lymphoid tissue.
2.

"Genomic organization and chromosomal location of the human gene encoding the B-lymphocyte activation antigen B7."
Selvakumar A. , Mohanraj B.K. , Eddy R.L. , Shows T.B. , White P.C. , Dupont B.
Immunogenetics36:175-181(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Human Soluble CD80 is generated by alternative splicing, and recombinant soluble CD80 binds to CD28 and CD152 influencing T-cell activation."
Kakoulidou M. , Giscombe R. , Zhao X. , Lefvert A.K. , Wang X.
Scand. J. Immunol.66:529-537(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);ALTERNATIVE SPLICING
4.

"The DNA sequence, annotation and analysis of human chromosome 3."
Muzny D.M. , Scherer S.E. , Kaul R. , Wang J. , Yu J. , Sudbrak R. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , more...
Nature440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue: Brain.
6.

"Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7."
Freeman G.J. , Gray G.S. , Gimmi C.D. , Lombard D.B. , Zhou L.-J. , White M. , Fingeroth J.D. , Gribben J.G. , Nadler L.M.
J. Exp. Med.174:625-631(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 35-38
7.

"CD80 (B7) and CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL."
Lanier L.L. , O'Fallon S. , Somoza C. , Phillips J.H. , Linsley P.S. , Okumura K. , Ito D. , Azuma M.
J. Immunol.154:97-105(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
8.

"Interaction of CTLA-4 (CD152) with CD80 or CD86 inhibits human T-cell activation."
Vandenborre K. , Van Gool S.W. , Kasran A. , Ceuppens J.L. , Boogaerts M.A. , Vandenberghe P.
Immunology98:413-421(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CTLA4
9.

"Members of adenovirus species B utilize CD80 and CD86 as cellular attachment receptors."
Short J.J. , Vasu C. , Holterman M.J. , Curiel D.T. , Pereboev A.
Virus Res.122:144-153(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ADENOVIRUS SUBGROUP B FIBER PROTEINS
10.

"Structure and dimerization of a soluble form of B7-1."
Ikemizu S. , Gilbert R.J. , Fennelly J.A. , Collins A.V. , Harlos K. , Jones E.Y. , Stuart D.I. , Davis S.J.
Immunity12:51-60(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 35-234
11.

"Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses."
Stamper C.C. , Zhang Y. , Tobin J.F. , Erbe D.V. , Ikemizu S. , Davis S.J. , Stahl M.L. , Seehra J. , Somers W.S. , Mosyak L.
Nature410:608-611(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 35-242 IN COMPLEX WITH CTLA4;SUBUNIT;DISULFIDE BONDS;GLYCOSYLATION AT ASN-53; ASN-89; ASN-186; ASN-207 AND ASN-226

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