Gene name:
CDC23 (ANAPC8) ;
Protein name:
Cell division cycle protein 23 homolog ;
Alternative:
Cyclosome subunit 8 ;Anaphase-promoting complex subunit 8 (APC8) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
The APC/C is composed of at least 12 subunits.
Function:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Attributes:
50:
MAASTSMVPV | AVTAAVAPVL | SINSDFSDLR | EIKKQLLLIA | GLTRERGLLH |
100:
SSKWSAELAF | SLPALPLAEL | QPPPPITEED | AQDMDAYTLA | KAYFDVKEYD |
150:
RAAHFLHGCN | SKKAYFLYMY | SRYLSGEKKK | DDETVDSLGP | LEKGQVKNEA |
200:
LRELRVELSK | KHQARELDGF | GLYLYGVVLR | KLDLVKEAID | VFVEATHVLP |
250:
LHWGAWLELC | NLITDKEMLK | FLSLPDTWMK | EFFLAHIYTE | LQLIEEALQK |
300:
YQNLIDVGFS | KSSYIVSQIA | VAYHNIRDID | KALSIFNELR | KQDPYRIENM |
350:
DTFSNLLYVR | SMKSELSYLA | HNLCEIDKYR | VETCCVIGNY | YSLRSQHEKA |
400:
ALYFQRALKL | NPRYLGAWTL | MGHEYMEMKN | TSAAIQAYRH | AIEVNKRDYR |
450:
AWYGLGQTYE | ILKMPFYCLY | YYRRAHQLRP | NDSRMLVALG | ECYEKLNQLV |
500:
EAKKCYWRAY | AVGDVEKMAL | VKLAKLHEQL | TESEQAAQCY | IKYIQDIYSC |
550:
GEIVEHLEES | TAFRYLAQYY | FKCKLWDEAS | TCAQKCCAFN | DTREEGKALL |
597:
RQILQLRNQG | ETPTTEVPAP | FFLPASLSAN | NTPTRRVSPL | NLSSVTP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Bovine
ELISA Kit for Human Cell division cycle protein 23 homolog
ELISA Kit for Human Cell division cycle protein 23 homolog
ELISA Kit for Human Cell division cycle protein 23 homolog
CLIA Kit for Human Cell division cycle protein 23 homolog
CLIA Kit for Human Cell division cycle protein 23 homolog
CLIA Kit for Human Cell division cycle protein 23 homolog
Polyclonal Antibody for Human Cell division cycle protein 23 homolog
Polyclonal Antibody for Human Cell division cycle protein 23 homolog
Polyclonal Antibody for Human Cell division cycle protein 23 homolog
Monoclonal Antibody for Human Cell division cycle protein 23 homolog
Monoclonal Antibody for Human Cell division cycle protein 23 homolog
Monoclonal Antibody for Human Cell division cycle protein 23 homolog
Protein for Human Cell division cycle protein 23 homolog
Protein for Human Cell division cycle protein 23 homolog
Protein for Human Cell division cycle protein 23 homolog
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
tissue :
Placenta .
tissue :
Uterus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANT GLN-78
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
Duodenum .
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Pancreas .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 2-597 (ISOFORM 1)
tissue :
Bone marrow .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 7-597 (ISOFORM 1)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-588 AND THR-596;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-588;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Cervix carcinoma .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-562; THR-582; SER-588; SER-593 AND THR-596;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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tissue :
Leukemic T-cell .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Sci. Signal.3:RA3-RA3(2010)
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PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-588 AND THR-596;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
19.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-588 AND THR-596;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Proc. Natl. Acad. Sci. U.S.A.109:12449-12454(2012)
[
PubMed ]
[
Europe PMC ]
[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
23.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ELECTRON MICROSCOPY OF THE APC/C
24.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY ELECTRON MICROSCOPY (7.4 ANGSTROMS) OF THE APC/C;SUBUNIT