Protein name:
Major centromere autoantigen B ;
Alternative:
Centromere protein B (CENP-B) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Homodimer. Interacts with CENPT.
Function:
Interacts with centromeric heterochromatin in chromosomes and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. May organize arrays of centromere satellite DNA into a higher order structure which then directs centromere formation and kinetochore assembly in mammalian chromosomes.
Subcellular Location:
Nucleus
Chromosome
centromere
Protein Attributes:
50:
MGPKRRQLTF | REKSRIIQEV | EENPDLRKGE | IARRFNIPPS | TLSTILKNKR |
100:
AILASERKYG | VASTCRKTNK | LSPYDKLEGL | LIAWFQQIRA | AGLPVKGIIL |
150:
KEKALRIAEE | LGMDDFTASN | GWLDRFRRRH | GVVSCSGVAR | ARARNAAPRT |
200:
PAAPASPAAV | PSEGSGGSTT | GWRAREEQPP | SVAEGYASQD | VFSATETSLW |
250:
YDFLPDQAAG | LCGGDGRPRQ | ATQRLSVLLC | ANADGSEKLP | PLVAGKSAKP |
300:
RAGQAGLPCD | YTANSKGGVT | TQALAKYLKA | LDTRMAAESR | RVLLLAGRLA |
350:
AQSLDTSGLR | HVQLAFFPPG | TVHPLERGVV | QQVKGHYRQA | MLLKAMAALE |
400:
GQDPSGLQLG | LTEALHFVAA | AWQAVEPSDI | AACFREAGFG | GGPNATITTS |
450:
LKSEGEEEEE | EEEEEEEEEG | EGEEEEEEGE | EEEEEGGEGE | ELGEEEEVEE |
500:
EGDVDSDEEE | EEDEESSSEG | LEAEDWAQGV | VEAGGSFGAY | GAQEEAQCPT |
550:
LHFLEGGEDS | DSDSEEEDDE | EEDDEDEDDD | DDEEDGDEVP | VPSFGEAMAY |
599:
FAMVKRYLTS | FPIDDRVQSH | ILHLEHDLVH | VTRKNHARQA | GVRGLGHQS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Major centromere autoantigen B
ELISA Kit for Human Major centromere autoantigen B
CLIA Kit for Human Major centromere autoantigen B
CLIA Kit for Human Major centromere autoantigen B
Polyclonal Antibody for Human Major centromere autoantigen B
Polyclonal Antibody for Human Major centromere autoantigen B
Monoclonal Antibody for Human Major centromere autoantigen B
Monoclonal Antibody for Human Major centromere autoantigen B
Protein for Human Major centromere autoantigen B
Protein for Human Major centromere autoantigen B
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
2.
"The DNA sequence and comparative analysis of human chromosome 20."
Deloukas P.
,
Matthews L.H.
,
Ashurst J.L.
,
Burton J.
,
Gilbert J.G.R.
,
Jones M.
,
Stavrides G.
,
Almeida J.P.
,
Babbage A.K.
,
Bagguley C.L.
,
Bailey J.
,
Barlow K.F.
,
Bates K.N.
,
Beard L.M.
,
Beare D.M.
,
Beasley O.P.
,
Bird C.P.
,
Blakey S.E.
,
Bridgeman A.M.
,
Brown A.J.
,
Buck D.
,
Burrill W.D.
,
Butler A.P.
,
Carder C.
,
Carter N.P.
,
Chapman J.C.
,
Clamp M.
,
Clark G.
,
Clark L.N.
,
Clark S.Y.
,
Clee C.M.
,
Clegg S.
,
Cobley V.E.
,
Collier R.E.
,
Connor R.E.
,
Corby N.R.
,
Coulson A.
,
Coville G.J.
,
Deadman R.
,
Dhami P.D.
,
Dunn M.
,
Ellington A.G.
,
Frankland J.A.
,
Fraser A.
,
French L.
,
Garner P.
,
Grafham D.V.
,
Griffiths C.
,
Griffiths M.N.D.
,
Gwilliam R.
,
Hall R.E.
,
Hammond S.
,
Harley J.L.
,
Heath P.D.
,
Ho S.
,
Holden J.L.
,
Howden P.J.
,
Huckle E.
,
Hunt A.R.
,
Hunt S.E.
,
Jekosch K.
,
Johnson C.M.
,
Johnson D.
,
Kay M.P.
,
Kimberley A.M.
,
King A.
,
Knights A.
,
Laird G.K.
,
Lawlor S.
,
Lehvaeslaiho M.H.
,
Leversha M.A.
,
Lloyd C.
,
Lloyd D.M.
,
Lovell J.D.
,
Marsh V.L.
,
Martin S.L.
,
McConnachie L.J.
,
McLay K.
,
McMurray A.A.
,
Milne S.A.
,
Mistry D.
,
Moore M.J.F.
,
Mullikin J.C.
,
Nickerson T.
,
Oliver K.
,
Parker A.
,
Patel R.
,
Pearce T.A.V.
,
Peck A.I.
,
Phillimore B.J.C.T.
,
Prathalingam S.R.
,
Plumb R.W.
,
Ramsay H.
,
Rice C.M.
,
Ross M.T.
,
Scott C.E.
,
Sehra H.K.
,
Shownkeen R.
,
Sims S.
,
Skuce C.D.
,
Smith M.L.
,
Soderlund C.
,
Steward C.A.
,
Sulston J.E.
,
Swann R.M.
,
Sycamore N.
,
Taylor R.
,
Tee L.
,
Thomas D.W.
,
Thorpe A.
,
Tracey A.
,
Tromans A.C.
,
Vaudin M.
,
Wall M.
,
Wallis J.M.
,
Whitehead S.L.
,
Whittaker P.
,
Willey D.L.
,
Williams L.
,
Williams S.A.
,
Wilming L.
,
Wray P.W.
,
Hubbard T.
,
Durbin R.M.
,
Bentley D.R.
,
Beck S.
,
Rogers J.
more...
Nature414:865-871(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Uterus .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 6-599
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT;DOMAINS
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH CENPT
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-156;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
10.
"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
Olsen J.V.
,
Vermeulen M.
,
Santamaria A.
,
Kumar C.
,
Miller M.L.
,
Jensen L.J.
,
Gnad F.
,
Cox J.
,
Jensen T.S.
,
Nigg E.A.
,
Brunak S.
,
Mann M.
Sci. Signal.3:RA3-RA3(2010)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-156; SER-165 AND THR-398;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Cervix carcinoma .
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : CLEAVAGE OF INITIATOR METHIONINE;METHYLATION AT GLY-2;MUTAGENESIS OF LYS-4
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 1-56
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 1-129 IN COMPLEX WITH DNA;H-T-H MOTIF
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (1.65 ANGSTROMS) OF 536-599;SUBUNIT