Gene name:
CERK (KIAA1646) ;
Protein name:
Ceramide kinase (hCERK) ;
Alternative:
Lipid kinase 4 (LK4) ;Acylsphingosine kinase ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
Subcellular Location:
Cytoplasm
Membrane
Peripheral membrane protein
Protein Attributes:
50:
MGATGAAEPL | QSVLWVKQQR | CAVSLEPARA | LLRWWRSPGP | GAGAPGADAC |
100:
SVPVSEIIAV | EETDVHGKHQ | GSGKWQKMEK | PYAFTVHCVK | RARRHRWKWA |
150:
QVTFWCPEEQ | LCHLWLQTLR | EMLEKLTSRP | KHLLVFINPF | GGKGQGKRIY |
200:
ERKVAPLFTL | ASITTDIIVT | EHANQAKETL | YEINIDKYDG | IVCVGGDGMF |
250:
SEVLHGLIGR | TQRSAGVDQN | HPRAVLVPSS | LRIGIIPAGS | TDCVCYSTVG |
300:
TSDAETSALH | IVVGDSLAMD | VSSVHHNSTL | LRYSVSLLGY | GFYGDIIKDS |
350:
EKKRWLGLAR | YDFSGLKTFL | SHHCYEGTVS | FLPAQHTVGS | PRDRKPCRAG |
400:
CFVCRQSKQQ | LEEEQKKALY | GLEAAEDVEE | WQVVCGKFLA | INATNMSCAC |
450:
RRSPRGLSPA | AHLGDGSSDL | ILIRKCSRFN | FLRFLIRHTN | QQDQFDFTFV |
500:
EVYRVKKFQF | TSKHMEDEDS | DLKEGGKKRF | GHICSSHPSC | CCTVSNSSWN |
537:
CDGEVLHSPA | IEVRVHCQLV | RLFARGIEEN | PKPDSHS
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human hCERK
ELISA Kit for Human hCERK
Polyclonal Antibody for Human hCERK
Polyclonal Antibody for Human hCERK
Monoclonal Antibody for Human hCERK
Monoclonal Antibody for Human hCERK
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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